YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|227082357, gi...
Organism:	Vibrio cholerae M66-2
Length:	247 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227082357, gi....

Description	E-value	Query Range	Subject Range
gi\|254286458, gi... - gi\|254286458\|ref\|ZP_04961415.1\| DNA polymerase III, epsilon subunit [Vibrio cholerae AM-19226], gi\|1... gi\|149741052, gi... - gi\|153825368\|ref\|ZP_01978035.1\| DNA polymerase III, epsilon subunit [Vibrio cholerae MZO-2], gi\|1497... gi\|183179467, gi... - gi\|183179467\|ref\|ZP_02957678.1\| DNA polymerase III, epsilon subunit [Vibrio cholerae MZO-3], gi\|1830... gi\|125621682, gi... - gi\|75820874\|ref\|ZP_00750912.1\| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonuc... gi\|229524236, gi... - gi\|229524236\|ref\|ZP_04413641.1\| DNA polymerase III epsilon subunit [Vibrio cholerae bv. albensis VL4... gi\|194535875, gi... - gi\|75824346\|ref\|ZP_00753803.1\| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonuc... tr\|D7HE18\|D7HE18... - DNA polymerase III, epsilon subunit OS=Vibrio cholerae GN=dnaQ PE=4 SV=1, DNA polymerase III, epsilo... gi\|229332537, gi... - gi\|229528763\|ref\|ZP_04418153.1\| DNA polymerase III epsilon subunit [Vibrio cholerae 12129(1)], gi\|22...	259.0	[0..1]	[247..1]
gi\|27365234, gi\|... - gi\|27365234\|ref\|NP_760762.1\| DNA polymerase III subunit epsilon [Vibrio vulnificus CMCP6], gi\|273613... gi\|37680713, gi\|... - gi\|37680713\|ref\|NP_935322.1\| DNA polymerase III subunit epsilon [Vibrio vulnificus YJ016], gi\|371994...	236.0	[0..1]	[246..1]
gi\|224582105, gi... - gi\|224582105\|ref\|YP_002635903.1\| DNA polymerase III subunit epsilon [Salmonella enterica subsp. ente... gi\|62126463, gi\|... - gi\|62178830\|ref\|YP_215247.1\| DNA polymerase III subunit epsilon [Salmonella enterica subsp. enterica...	236.0	[0..3]	[247..2]
gi\|238794443, gi... - gi\|77977838\|ref\|ZP_00833277.1\| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonuc...	234.0	[0..1]	[246..1]
gi\|27479696 - gi\|27479696\|gb\|AAO17223.1\| DnaQ [Photorhabdus luminescens]	234.0	[0..5]	[246..1]
gi\|207855776, gi... - gi\|207855776\|ref\|YP_002242427.1\| DNA polymerase III subunit epsilon [Salmonella enterica subsp. ente... gi\|205271376, gi... - gi\|205351595\|ref\|YP_002225396.1\| DNA polymerase III subunit epsilon [Salmonella enterica subsp. ente... gi\|16759250 - gi\|16759250\|ref\|NP_454867.1\| DNA polymerase III subunit epsilon [Salmonella enterica subsp. enterica... gi\|197095021, gi... - gi\|197363544\|ref\|YP_002143181.1\| DNA polymerase III subunit epsilon [Salmonella enterica subsp. ente... DPO3E_SALTY - DNA polymerase III subunit epsilon OS=Salmonella typhimurium GN=dnaQ PE=3 SV=1 gi\|56414616, gi\|... - gi\|56414616\|ref\|YP_151691.1\| DNA polymerase III subunit epsilon [Salmonella enterica subsp. enterica... lcl\|NC_016856.1_... - [gene=dnaQ] [protein=DNA polymerase III subunit epsilon] [protein_id=YP_005235932.1] [location=30410... DPO3E_SALTY - DNA polymerase III subunit epsilon OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) G... gi\|29142975, gi\|... - gi\|29142975\|ref\|NP_806317.1\| DNA polymerase III subunit epsilon [Salmonella enterica subsp. enterica... DPO3E_SALTI - DNA polymerase III subunit epsilon OS=Salmonella typhi GN=dnaQ PE=3 SV=1 DP3E_SALTY, DPO3... - DNA polymerase III subunit epsilon OS=Salmonella typhimurium GN=dnaQ PE=3 SV=1, (P14566) DNA polymer... DPO3E_SALTI - DNA polymerase III subunit epsilon OS=Salmonella typhi GN=dnaQ PE=3 SV=1	234.0	[0..5]	[247..1]
gi\|77957728, gi\|... - gi\|77957728\|ref\|ZP_00821776.1\| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonuc...	233.0	[0..1]	[246..1]
gi\|26106556, gi\|... - gi\|26246159\|ref\|NP_752198.1\| DNA polymerase III subunit epsilon [Escherichia coli CFT073], gi\|261065... gi\|91070857, gi\|... - gi\|91209283\|ref\|YP_539269.1\| DNA polymerase III subunit epsilon [Escherichia coli UTI89], gi\|9107085... gi\|117622497, gi... - gi\|117622497\|ref\|YP_851410.1\| DNA polymerase III subunit epsilon [Escherichia coli APEC O1], gi\|1155... gi\|227838235, gi... - gi\|227884794\|ref\|ZP_04002599.1\| DNA polymerase III subunit epsilon [Escherichia coli 83972], gi\|2278... gi\|226899002, gi... - gi\|237707792\|ref\|ZP_04538273.1\| DNA polymerase subunit III epsilon [Escherichia sp. 3_2_53FAA], gi\|2...	232.0	[0..3]	[247..2]
gi\|75241725 - gi\|75241725\|ref\|ZP_00725562.1\| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonuc... gi\|110640430, gi... - gi\|110640430\|ref\|YP_668158.1\| DNA polymerase III subunit epsilon [Escherichia coli 536], gi\|11034202...	232.0	[0..3]	[247..2]
gi\|108776724, gi... - gi\|229903519\|ref\|ZP_04518632.1\| DNA polymerase III epsilon subunit [Yersinia pestis Nepal516], gi\|22... gi\|21960013, gi\|... - gi\|22126970\|ref\|NP_670393.1\| DNA polymerase III subunit epsilon [Yersinia pestis KIM], gi\|21960013\|g... gi\|25299959 - pir\|\|AB0133 DNA-directed DNA polymerase (EC 2.7.7.7) epsilon chain [imported] - Yersinia pestis (str... gi\|51597279, gi\|... - gi\|51597279\|ref\|YP_071470.1\| DNA polymerase III subunit epsilon [Yersinia pseudotuberculosis IP 3295... gi\|45442535, gi\|... - gi\|45442535\|ref\|NP_994074.1\| DNA polymerase III subunit epsilon [Yersinia pestis biovar Microtus str... gi\|149366915, gi... - gi\|149366915\|ref\|ZP_01888949.1\| DNA polymerase III, epsilon chain [Yersinia pestis CA88-4125], gi\|14... gi\|166207576, gi... - gi\|166211805\|ref\|ZP_02237840.1\| DNA polymerase III, epsilon subunit [Yersinia pestis biovar Antiqua ... gi\|218928251, gi... - gi\|218928251\|ref\|YP_002346126.1\| DNA polymerase III subunit epsilon [Yersinia pestis CO92], gi\|16121... gi\|162352279, gi... - gi\|77633043\|ref\|ZP_00795199.1\| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonuc... gi\|145210608, gi... - gi\|145598912\|ref\|YP_001162988.1\| DNA polymerase III subunit epsilon [Yersinia pestis Pestoides F], g... gi\|166011939, gi... - gi\|166011939\|ref\|ZP_02232837.1\| DNA polymerase III, epsilon subunit [Yersinia pestis biovar Antiqua ... gi\|152959968, gi... - gi\|77629997\|ref\|ZP_00792583.1\| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonuc... gi\|166962610, gi... - gi\|167419869\|ref\|ZP_02311622.1\| DNA polymerase III, epsilon subunit [Yersinia pestis biovar Oriental... gi\|167050647, gi... - gi\|167399939\|ref\|ZP_02305457.1\| DNA polymerase III, epsilon subunit [Yersinia pestis biovar Antiqua ... gi\|169749889, gi... - gi\|170023355\|ref\|YP_001719860.1\| DNA polymerase III subunit epsilon [Yersinia pseudotuberculosis YPI... gi\|167424264, gi... - gi\|167424264\|ref\|ZP_02316017.1\| DNA polymerase III, epsilon subunit [Yersinia pestis biovar Mediaeva... gi\|186699410, gi... - gi\|186896384\|ref\|YP_001873496.1\| DNA polymerase III subunit epsilon [Yersinia pseudotuberculosis PB1... Q667M8\|Q667M8_YERPS - DNA polymerase III, epsilon chain - Yersinia pseudotuberculosis gi\|165938341, gi... - gi\|89102979\|ref\|ZP_01175578.1\| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonuc... gi\|108778470, gi... - gi\|108806557\|ref\|YP_650473.1\| DNA polymerase III subunit epsilon [Yersinia pestis Antiqua], gi\|10877... gi\|229841013, gi... - gi\|229841013\|ref\|ZP_04461172.1\| DNA polymerase III epsilon subunit [Yersinia pestis biovar Orientali... gi\|229689465, gi... - gi\|229843118\|ref\|ZP_04463264.1\| DNA polymerase III epsilon subunit [Yersinia pestis biovar Orientali... gi\|229895464, gi... - gi\|229895464\|ref\|ZP_04510636.1\| DNA polymerase III epsilon subunit [Yersinia pestis Pestoides A], gi... gi\|165924368, gi... - gi\|165924368\|ref\|ZP_02220200.1\| DNA polymerase III, epsilon subunit [Yersinia pestis biovar Oriental...	232.0	[0..5]	[246..1]

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Predicted Domain #1

Region A:
Residues: [1-247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTSNNAEYQ RIVVLDTETT GMNREGGPHY EGHRIIEIGA VEIINRKLTG RHFHVYLKPD  60
   61 RDIQLEAIEV HGITDEFLKD KPEYKDVHEE FVDFIKGAEL VAHNAPFDVG FMDYEFAKLG 120
  121 GAIGKTSDFC KVTDTLAMAK RIFPGKRNNL DILCERYGID NSHRTLHGAL LDAEILADVY 180
  181 LLMTGGQTSL QFSSVTQNSG ELSAESLKRA RSERKALKVL AASADELQAH QDRLDIVAKS 240
  241 GTCLWRS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.69897
Match:	2guiA
Description:	No description for 2guiA was found.

Predicted functions:

Term	Confidence	Notes
DNA polymerase activity	7.87431862983329	bayes_pls_golite062009
DNA-directed DNA polymerase activity	7.78411937387917	bayes_pls_golite062009
nucleotidyltransferase activity	5.3880945520411	bayes_pls_golite062009
exonuclease activity	2.86892175148145	bayes_pls_golite062009
nuclease activity	2.84202779131927	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1.94077739152313	bayes_pls_golite062009
deoxyribonuclease activity	1.87431870698721	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.87430802282815	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.75713164321634	bayes_pls_golite062009
transferase activity	1.47288345517763	bayes_pls_golite062009
ribonuclease activity	1.41871623152578	bayes_pls_golite062009
catalytic activity	1.25233849524628	bayes_pls_golite062009
endonuclease activity	0.935348031740788	bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.782108781904855	bayes_pls_golite062009
exodeoxyribonuclease activity	0.77421125364834	bayes_pls_golite062009
3'-5' exonuclease activity	0.64268174969672	bayes_pls_golite062009
endodeoxyribonuclease activity	0.48776342704945	bayes_pls_golite062009
exoribonuclease activity	0.26279899872348	bayes_pls_golite062009
nucleic acid binding	0.251640316483416	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	0.18445559832317	bayes_pls_golite062009
single-stranded DNA specific 3'-5' exodeoxyribonuclease activity	0.1355017328177	bayes_pls_golite062009
binding	0.122249780594036	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: