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View Structure Prediction Details

Protein: rdgBbeta-PA
Organism: Drosophila melanogaster
Length: 273 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rdgBbeta-PA.

Description E-value Query
Range
Subject
Range
gi|109497331 - gi|109497331|ref|XP_001079124.1| PREDICTED: similar to retinal degeneration B2 homolog [Rattus norve...
448.0 [0..2] [271..1]

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Predicted Domain #1
Region A:
Residues: [1-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLIKEYRVC MPLTVEEYKI GQLYMIARHS LEQSEEGEGV EVVENKPCED PVHGKGQYTE  60
   61 KHIHLSSRLP YWIQAICPRV FYVIEKSWNY YPYTLTEYTC SFIPKLNVLI KTKYEDNNGS 120
  121 TENCLDLTED ELKVRTVDHL DIAFDEVSAK HYKKEEDPKF FKSEKTNRGP LIEGWRETDK 180
  181 PIMCSYKVVH ASFEVWGLQT KVEDFIQRGI REILLLGHRQ AFAWVDEWHG MTLEDVRAYE 240
  241 RQKQAETNEK IHNTSGGANA AANAKEANDG DID

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.0
Match: 1t27A
Description: THE STRUCTURE OF PITP COMPLEXED TO PHOSPHATIDYLCHOLINE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipid transporter activity 5.13837461289632 bayes_pls_golite062009
lipid transporter activity 4.4358073696145 bayes_pls_golite062009
phosphatidylinositol transporter activity 2.88424241201993 bayes_pls_golite062009
transporter activity 2.27726025087174 bayes_pls_golite062009
substrate-specific transporter activity 2.15798050058248 bayes_pls_golite062009
binding 2.03322388415011 bayes_pls_golite062009
sterol binding 1.50607153716429 bayes_pls_golite062009
cholesterol binding 1.15123926171731 bayes_pls_golite062009
transmembrane transporter activity 1.09413284791115 bayes_pls_golite062009
phosphatidylcholine transmembrane transporter activity 0.917631923888787 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.584604660695011 bayes_pls_golite062009
cholesterol transporter activity 0.478721911308239 bayes_pls_golite062009
protein binding 0.43929659331502 bayes_pls_golite062009
sterol transporter activity 0.35901111584592 bayes_pls_golite062009
ion transmembrane transporter activity 0.295257921753146 bayes_pls_golite062009
active transmembrane transporter activity 0.286459038638072 bayes_pls_golite062009
primary active transmembrane transporter activity 0.265156292873733 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.256503527440737 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.21859262454477 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.215063584310921 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.214776368903272 bayes_pls_golite062009
lipid binding 0.144022082146249 bayes_pls_golite062009
steroid binding 0.136743971526566 bayes_pls_golite062009
cation transmembrane transporter activity 0.0954103313829049 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0415343979510595 bayes_pls_golite062009
catalytic activity 0.0116392906163881 bayes_pls_golite062009
pyrophosphatase activity 0.00274551209125462 bayes_pls_golite062009

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