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View Structure Prediction Details

Protein: GMK3_ARATH
Organism: Arabidopsis thaliana
Length: 282 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GMK3_ARATH.

Description E-value Query
Range
Subject
Range
gi|45681510, gi|... - ref|ZP_00192950.1| COG5265: ABC-type transport system involved in Fe-S cluster assembly, permease an...
248.0 [0..2] [279..305]

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Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRKLCSSFS RSIIFPNKPI FIPRSFPQPL RHSSALSYSS LKMTDTHIPG NPNSSPIQSP  60
   61 TKPESLRSLE FQLGS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.526 a.4.5 "Winged helix" DNA-binding domain
View Download 0.423 a.64.2 Bacteriocin AS-48
View Download 0.358 a.4.5 "Winged helix" DNA-binding domain
View Download 0.355 a.4.5 "Winged helix" DNA-binding domain
View Download 0.352 a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #2
Region A:
Residues: [76-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFTADPIIPP PNQIVIVISG PSGVGKDAVI NKLREVREGL HFVVTATSRP MRPGEVDGKD  60
   61 YFFVSRDQFL SMVENEELLE YALVYGEYKG IPKKQIQEFM AKGEDIVLRV DIQGAQTLRR 120
  121 ILGNSAVFIF LVAESELAMV ERLIDRKTES QEELLVRVAT AREEVRHLKN FDYVVVNAKG 180
  181 RLDDAVNRVE SIIDAEKSKV HQRIVRI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1s96A
Description: The 2.0 A X-ray structure of Guanylate Kinase from E.coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 3.66392587433723 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 3.47528445676761 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 2.55741461337855 bayes_pls_golite062009
substrate-specific transporter activity 2.54103332067513 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 2.40650518173039 bayes_pls_golite062009
nucleotide kinase activity 2.24094813695083 bayes_pls_golite062009
kinase activity 2.0779386406753 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 1.96697952975573 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.92480060698169 bayes_pls_golite062009
binding 1.89648142312455 bayes_pls_golite062009
ion transmembrane transporter activity 1.69194088788064 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.60317778681063 bayes_pls_golite062009
cation transmembrane transporter activity 1.48327844851166 bayes_pls_golite062009
nucleic acid binding 1.08697924060619 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
nucleotide binding 0.828524126097217 bayes_pls_golite062009
purine ribonucleotide binding 0.810407092593521 bayes_pls_golite062009
ribonucleotide binding 0.810379637652019 bayes_pls_golite062009
purine nucleotide binding 0.805605269661092 bayes_pls_golite062009
DNA binding 0.702147676354075 bayes_pls_golite062009
adenylate kinase activity 0.447752711852745 bayes_pls_golite062009
hydrolase activity 0.420858111948277 bayes_pls_golite062009
transcription regulator activity 0.287777990975748 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009

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