YRC Public Data Repository - Protein Structure Prediction

Protein:	HINT1_RABIT
Organism:	Oryctolagus cuniculus
Length:	126 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HINT1_RABIT.

Description	E-value	Query Range	Subject Range
gi\|110762076 - gi\|110762076\|ref\|XP_625049.2\| PREDICTED: similar to CG2862-PA, isoform A [Apis mellifera]	157.0	[0..1]	[126..79]
gi\|220958568, gi... - gi\|220958568\|gb\|ACL91827.1\| CG2862-PA [synthetic construct], gi\|220949348\|gb\|ACL87217.1\| CG2862-PA [... gi\|195342081, gi... - gi\|195342081\|ref\|XP_002037630.1\| GM18366 [Drosophila sechellia], gi\|194132480\|gb\|EDW54048.1\| GM18366... gi\|195576145, gi... - gi\|195576145\|ref\|XP_002077937.1\| GD23182 [Drosophila simulans], gi\|194189946\|gb\|EDX03522.1\| GD23182 ... CG2862-PA, FBpp0... - This gene is referred to in FlyBase by the symbol Dmel\CG2862 (CG2862, FBgn0031459). It is a protein...	156.0	[0..1]	[126..25]
gi\|47218227 - gi\|47218227\|emb\|CAF97091.1\| unnamed protein product [Tetraodon nigroviridis]	156.0	[0..1]	[126..1]
gi\|7658009 - gi\|7658009\|dbj\|BAA94873.1\| protein kinase C inhibitor [Anas platyrhynchos] gi\|7658005 - gi\|7658005\|dbj\|BAA94871.1\| protein kinase C inhibitor [Coturnix japonica]	156.0	[0..1]	[126..1]
gi\|7415601, gi\|7... - gi\|7415603\|dbj\|BAA93455.1\| protein kinase C inhibitor [Gallus gallus], gi\|7415601\|dbj\|BAA93454.1\| pr...	156.0	[0..1]	[126..1]
gi\|51873772, gi\|... - gi\|51873772\|gb\|AAH78475.1\| MGC85233 protein [Xenopus laevis], gi\|147907158\|ref\|NP_001087193.1\| MGC85...	154.0	[0..1]	[126..1]
gi\|51980436, gi\|... - ref\|NP_001005593.1\| zgc:103764 [Danio rerio], gi\|51980436\|gb\|AAH81526.1\| Zgc:103764 [Danio rerio], ...	153.0	[0..1]	[126..1]
gi\|21228060, gi\|... - gi\|21228060\|ref\|NP_633982.1\| Hit-like protein [Methanosarcina mazei Go1], gi\|20906495\|gb\|AAM31654.1\|...	153.0	[0..9]	[122..1]
gi\|109490737 - gi\|109490737\|ref\|XP_001074494.1\| PREDICTED: similar to Histidine triad nucleotide-binding protein 1 ...	152.0	[0..1]	[126..68]

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Predicted Domain #1

Region A:
Residues: [1-126]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEIAKAQV ARPGGDTIFG KIIRKEIPAK IIFEDDQCLA FHDISPQAPT HFLVIPKKHI  60
   61 SQISAAEDAD ESLLGHLMIV GKKCAADLGL KKGYRMVVNE GSDGGQSVYH VHLHVLGGRQ 120
  121 MNWPPG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.0
Match:	1rzyA
Description:	Crystal structure of rabbit Hint complexed with N-ethylsulfamoyladenosine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.71599870633602	bayes_pls_golite062009
pyrophosphatase activity	1.08634513422834	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.06844766073798	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.06801208560744	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.5306871213471	bayes_pls_golite062009
nucleic acid binding	0.415463551462796	bayes_pls_golite062009
protein binding	0.315946879872005	bayes_pls_golite062009
hydrolase activity	0.196597931631016	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: