YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49259509, gi\|...
Organism:	Escherichia coli
Length:	228 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49259509, gi|....

Description	E-value	Query Range	Subject Range
gi\|84786146, gi\|... - gi\|85373063\|ref\|YP_457125.1\| pseudouridine synthase D large subunit [Erythrobacter litoralis HTCC259...	267.0	[0..2]	[223..88]
gi\|114843803, gi... - gi\|114843803\|ref\|ZP_01454263.1\| Pseudouridine synthase, RluD [Thermoanaerobacter ethanolicus X514], ...	266.0	[0..2]	[227..83]
gi\|90961803, gi\|... - gi\|90961803\|ref\|YP_535719.1\| ribosomal large subunit pseudouridine synthase D [Lactobacillus salivar...	266.0	[0..2]	[222..77]
gi\|85816530, gi\|... - gi\|86132824\|ref\|ZP_01051415.1\| ribosomal large subunit pseudouridine synthase D [Cellulophaga sp. ME...	265.0	[0..2]	[225..97]
gi\|76587739, gi\|... - gi\|76796894\|ref\|ZP_00779243.1\| Pseudouridine synthase, RluD [Thermoanaerobacter ethanolicus ATCC 332...	264.0	[0..2]	[227..83]
gi\|28211276, gi\|... - gi\|28211276\|ref\|NP_782220.1\| ribosomal large subunit pseudouridine synthase D [Clostridium tetani E8...	264.0	[0..2]	[227..82]
gi\|221322942 - gi\|221322942\|ref\|ZP_03604236.1\| hypothetical protein BsubsS_08522 [Bacillus subtilis subsp. subtilis... gi\|221318669 - gi\|221318669\|ref\|ZP_03599963.1\| hypothetical protein BsubsJ_08416 [Bacillus subtilis subsp. subtilis... gi\|221313745 - gi\|221313745\|ref\|ZP_03595550.1\| hypothetical protein BsubsN3_08482 [Bacillus subtilis subsp. subtili... YLYB_BACSU - Uncharacterized RNA pseudouridine synthase YlyB OS=Bacillus subtilis (strain 168) GN=ylyB PE=3 SV=3 YLYB_BACSU - Uncharacterized RNA pseudouridine synthase ylyB OS=Bacillus subtilis GN=ylyB PE=3 SV=3	263.0	[0..2]	[227..80]
gi\|20807974, gi\|... - gi\|20807974\|ref\|NP_623145.1\| pseudouridylate synthase, 23S RNA-specific [Thermoanaerobacter tengcong... gi\|20807974 - gi\|20807974\|ref\|NP_623145.1\| Pseudouridylate synthase, 23S RNA-specific [Thermoanaerobacter tengcong...	262.0	[0..2]	[228..82]
gi\|48870566, gi\|... - gi\|48870566\|ref\|ZP_00323287.1\| COG0564: Pseudouridylate synthases, 23S RNA-specific [Pediococcus pen...	261.0	[0..2]	[225..79]
gi\|52080148, gi\|... - gi\|52785525\|ref\|YP_091354.1\| YlyB [Bacillus licheniformis ATCC 14580], gi\|52348027\|gb\|AAU40661.1\| Yl...	260.0	[0..2]	[228..80]

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Predicted Domain #1

Region A:
Residues: [1-228]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADVIXYEDDH ILVLNKPSGT AVHGGSGLSF GVIEGLRALR PEARFLELVH RLDRDTSGVL  60
   61 LVAKKRSALR SLHEQLREKG XQKDYLALVR GQWQSHVKSV QAPLLKNILQ SGERIVRVSQ 120
  121 EGKPSETRFK VEERYAFATL VRCSPVTGRT HQIRVHTQYA GHPIAFDDRY GDREFDRQLT 180
  181 EAGTGLNRLF LHAAALKFTH PGTGEVXRIE APXDEGLKRC LQKXRNAR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.154902
Match:	1v9kA
Description:	The crystal structure of the catalytic domain of pseudouridine synthase RluC from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pseudouridine synthase activity	5.60483019625575	bayes_pls_golite062009
intramolecular transferase activity	4.62815459483632	bayes_pls_golite062009
isomerase activity	3.43067391737824	bayes_pls_golite062009
catalytic activity	2.39224964671205	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: