YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49258768, gi\|...
Organism:	Homo sapiens
Length:	122 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49258768, gi|....

Description	E-value	Query Range	Subject Range
gi\|109093125 - gi\|109093125\|ref\|XP_001097284.1\| PREDICTED: cystatin SA [Macaca mulatta]	158.0	[0..2]	[121..22]
gi\|55651412 - gi\|55651412\|ref\|XP_514555.1\| PREDICTED: similar to Cystatin SA precursor (Cystatin S5) isoform 3 [Pa...	153.0	[0..2]	[121..22]
CYTC_SAISC - Cystatin-C OS=Saimiri sciureus GN=CST3 PE=2 SV=1	151.0	[0..1]	[121..26]
gi\|18204598, gi\|... - gi\|19882251\|ref\|NP_001889.2\| cystatin SN precursor [Homo sapiens], gi\|18204598\|gb\|AAH21225.1\| Cystat...	151.0	[0..2]	[121..22]
gi\|60831800 - gi\|60831800\|gb\|AAX36984.1\| cystatin C [synthetic construct]	149.0	[0..1]	[121..26]

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Predicted Domain #1

Region A:
Residues: [1-122]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSASAQSRTL AGGIHATDLN DKSVQRALDF AISEYNKVIN KDEYYSRPLQ VMAAYQQIVG  60
   61 GVNYYFNVKF GRTTCTKSQP NLDNCPFNDQ PKLKEEEFCS FQINEVPWED KISILNYKCR 120
  121 KV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.522879
Match:	1rn7A
Description:	Structure of human cystatin D
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protease binding	0.641761143986125	bayes_pls_golite062009
endopeptidase inhibitor activity	0.425078812345947	bayes_pls_golite062009
peptidase inhibitor activity	0.42207410200052	bayes_pls_golite062009
enzyme inhibitor activity	0.319020194107693	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: