YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|170709286, gi...
Organism:	Bacillus anthracis str. A0389
Length:	666 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|170709286, gi....

Description	E-value	Query Range	Subject Range
gi\|42782768, gi\|... - gi\|42782768\|ref\|NP_980015.1\| transketolase [Bacillus cereus ATCC 10987], gi\|42738695\|gb\|AAS42623.1\| ...	0.0	[1..666]	[1..666]
gi\|30021779, gi\|... - gi\|30021779\|ref\|NP_833410.1\| transketolase [Bacillus cereus ATCC 14579], gi\|29897335\|gb\|AAP10611.1\| ... gi\|228723990, gi... - gi\|229047365\|ref\|ZP_04192963.1\| Transketolase [Bacillus cereus AH676], gi\|228723990\|gb\|EEL75337.1\| T... gi\|228959871, gi... - gi\|228959871\|ref\|ZP_04121544.1\| Transketolase [Bacillus thuringiensis serovar pakistani str. T13001]... gi\|228631583, gi... - gi\|229151878\|ref\|ZP_04280076.1\| Transketolase [Bacillus cereus m1550], gi\|228631583\|gb\|EEK88214.1\| T... gi\|228637307, gi... - gi\|229146248\|ref\|ZP_04274623.1\| Transketolase [Bacillus cereus BDRD-ST24], gi\|228637307\|gb\|EEK93762.... gi\|206736052, gi... - gi\|206969011\|ref\|ZP_03229966.1\| transketolase [Bacillus cereus AH1134], gi\|206736052\|gb\|EDZ53210.1\| ... gi\|228654500, gi... - gi\|229128955\|ref\|ZP_04257930.1\| Transketolase [Bacillus cereus BDRD-Cer4], gi\|228654500\|gb\|EEL10363....	0.0	[1..666]	[15..680]
gi\|49478325, gi\|... - gi\|49478325\|ref\|YP_037757.1\| transketolase [Bacillus thuringiensis serovar konkukian str. 97-27], gi...	0.0	[1..666]	[1..666]
gi\|163941287, gi... - gi\|89209315\|ref\|ZP_01187752.1\| transketolase [Bacillus weihenstephanensis KBAB4], gi\|89152757\|gb\|EAR... gi\|229134484, gi... - gi\|229134484\|ref\|ZP_04263297.1\| Transketolase [Bacillus cereus BDRD-ST196], gi\|228649105\|gb\|EEL05127...	0.0	[1..666]	[1..666]
gi\|152024812, gi... - gi\|89203693\|ref\|ZP_01182300.1\| transketolase [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|89148...	0.0	[1..666]	[1..666]
gi\|47554080, gi\|... - gi\|47569206\|ref\|ZP_00239892.1\| transketolase [Bacillus cereus G9241], gi\|47554080\|gb\|EAL12445.1\| tra...	0.0	[1..666]	[1..666]
gi\|51975328, gi\|... - gi\|52141859\|ref\|YP_084972.1\| transketolase [Bacillus cereus E33L], gi\|51975328\|gb\|AAU16878.1\| transk... gi\|222097146, gi... - gi\|222097146\|ref\|YP_002531203.1\| transketolase [Bacillus cereus Q1], gi\|221241204\|gb\|ACM13914.1\| tra... gi\|217065730, gi... - gi\|217961116\|ref\|YP_002339684.1\| transketolase [Bacillus cereus AH187], gi\|217065730\|gb\|ACJ79980.1\| ...	0.0	[1..666]	[1..666]
gi\|22777355, gi\|... - gi\|23099127\|ref\|NP_692593.1\| transketolase [Oceanobacillus iheyensis HTE831], gi\|22777355\|dbj\|BAC136...	0.0	[1..666]	[1..665]
gi\|168826063, gi... - gi\|32029978\|ref\|ZP_00132914.1\| COG0021: Transketolase [Haemophilus somnus 2336], gi\|170717934\|ref\|YP...	0.0	[6..666]	[4..668]
gi\|52080411, gi\|... - gi\|52785790\|ref\|YP_091619.1\| Tkt [Bacillus licheniformis ATCC 14580], gi\|52348292\|gb\|AAU40926.1\| Tkt...	0.0	[4..666]	[3..665]

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Predicted Domain #1

Region A:
Residues: [1-666]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHSIEQLSI NTIRTLSIDA IEKANSGHPG MPMGAAPMAY TLWTQFMKHN PNNPTWFNRD  60
   61 RFVLSAGHGS MLLYSLLHLS GYDVTMDDLK NFRQWGSKTP GHPEYGHTAG VDATTGPLGQ 120
  121 GIATAVGMAM AERHLAAKYN RDAYNIVDHY TYAICGDGDL MEGVSAEASS LAAHLQLGRL 180
  181 VVLYDSNDIS LDGDLNRSFS ESVEDRYKAY GWQVIRVEDG NDIEAIAKAI EEAKADEKRP 240
  241 TLIEVRTTIG FGSPNKSGKS ASHGSPLGVE ETKLTKEAYA WTAEQDFHVA EEVYENFRKT 300
  301 VQDVGETAQA EWNTMLGEYA QAYPELANEL QAAMNGLLPE GWEQNLPTYE LGSKAATRNS 360
  361 SGAVINAIAE SVPSFFGGSA DLAGSNKTYM NNEKDFTRDD YSGKNIWYGV REFAMGAAMN 420
  421 GIALHGGLKT YGGTFFVFSD YLRPAIRLAA LMQLPVTYVF THDSIAVGED GPTHEPIEQL 480
  481 AALRAMPNVS VIRPADGNES VAAWRLALES TNKPTALVLT RQDLPTLEGA KDDTYEKVAK 540
  541 GAYVVSASKK ETADVILLAT GSEVSLAVEA QKALAVDGVD ASVVSMPSMD RFEAQTAEYK 600
  601 ESVLPKAVTK RFAIEMGATF GWHRYVGLEG DVLGIDTFGA SAPGEKIMEE YGFTVENVVR 660
  661 KVKEML

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	173.0
Match:	1qgdA
Description:	Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transketolase activity	6.17852985073866	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	2.93250853993668	bayes_pls_golite062009
pyruvate dehydrogenase activity	2.81702263447118	bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity	2.6977837113283	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.21959520697519	bayes_pls_golite062009
binding	0.980920092099572	bayes_pls_golite062009
catalytic activity	0.545407789079971	bayes_pls_golite062009
acetolactate synthase activity	0.159086519260601	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: