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View Structure Prediction Details

Protein: PNP_CAUCN
Organism: Caulobacter crescentus NA1000
Length: 712 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNP_CAUCN.

Description E-value Query
Range
Subject
Range
gi|25311841, gi|... - pir||AE2586 polyribonucleotide nucleotidyltransferase pnpA [imported] - Agrobacterium tumefaciens (s...
PNP_AGRFC - Polyribonucleotide nucleotidyltransferase OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=pnp P...
734.0 [0..1] [712..1]

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Predicted Domain #1
Region A:
Residues: [1-712]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDIKRKTIE WGGKTLVLET GRIARQADGA VLATMGETVV LATAVFAKSQ KPGQDFFPLT  60
   61 VNYQEKTFAA GKIPGGFFKR EGRPSEKETL VSRLIDRPIR PLFVKGFKNE VQVVVTVLQH 120
  121 DLENDPDILG MVAASAALCL SGAPFMGPIG AARVGWVDGA YVLNPTLDEM KESKMDLVVA 180
  181 GTADAVMMVE SEIQELSEEI VLGGVNFAHQ QMQAVIDAII DLAEHAAKEP FAFEPEDTDA 240
  241 IKAKMKDLVG ADIAAAYKIQ KKQDRYEAVG AAKKKAIAAL GLSDENPTGY DPLKLGAIFK 300
  301 ELEADVVRRG ILDTGLRIDG RDVKTVRPIL GEVGILPRTH GSALFTRGET QAIVVATLGT 360
  361 GDDEQFIDAL EGTYKESFLL HYNFPPYSVG ETGRMGSPGR REIGHGKLAW RALRPMLPTK 420
  421 EDFPYTIRLV SEITESNGSS SMATVCGSSL AMMDAGVPLV RPVSGIAMGL ILEQDGFAVL 480
  481 SDILGDEDHL GDMDFKVAGT SEGLTSLQMD IKIAGITPAI MEQALAQAKE GRAHILGEMN 540
  541 KAMDAPRADV GDFAPKIETI NIPTDKIREV IGSGGKVIRE IVATTGAKVD INDDGVVKVS 600
  601 ASDGAKIKAA IDWIKSITDE AEVGKIYDGK VVKVVDFGAF VNFFGAKDGL VHVSQISNER 660
  661 VAKPSDVLKE GQMVKVKLLG FDDRGKTKLS MKVVDQETGE DLSKKEAAAE EA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 153.0
Match: 1e3hA
Description: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 3.62650207668685 bayes_pls_golite062009
transcription regulator activity 2.64513435028798 bayes_pls_golite062009
exoribonuclease activity 2.49584565422948 bayes_pls_golite062009
3'-5'-exoribonuclease activity 2.48625785660839 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 2.46667410843173 bayes_pls_golite062009
RNA binding 1.96263727771326 bayes_pls_golite062009
nucleic acid binding 1.06121115244578 bayes_pls_golite062009
transcription termination factor activity 1.01993495617192 bayes_pls_golite062009
binding 0.953779727473657 bayes_pls_golite062009
structural constituent of ribosome 0.82905129800799 bayes_pls_golite062009
ATP-dependent peptidase activity 0.66778558090199 bayes_pls_golite062009
structural molecule activity 0.61730676636766 bayes_pls_golite062009
carbohydrate kinase activity 0.51810239718467 bayes_pls_golite062009
DNA binding 0.42372608430605 bayes_pls_golite062009
0.416217645025381 bayes_pls_golite062009
hydrolase activity 0.355379071501158 bayes_pls_golite062009
catalytic activity 0.10089766806364 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0287026367466632 bayes_pls_golite062009

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