YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|220959066, gi...
Organism:	synthetic construct
Length:	211 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220959066, gi....

Description	E-value	Query Range	Subject Range
gi\|3550341 - gi\|3550341\|gb\|AAC34860.1\| cellular repressor of E1A-stimulated genes CREG [Drosophila melanogaster]	245.0	[0..1]	[211..1]
CREG1_MOUSE - Protein CREG1 OS=Mus musculus GN=Creg1 PE=1 SV=1	208.0	[0..18]	[210..26]
gi\|183986027, gi... - gi\|183986027\|gb\|AAI66446.1\| Cellular repressor of E1A-stimulated genes 1 [Rattus norvegicus], gi\|157...	199.0	[0..18]	[210..26]
gi\|54638069, gi\|... - gi\|54638069\|gb\|EAL27471.1\| GA18865-PA [Drosophila pseudoobscura], gi\|125774149\|ref\|XP_001358333.1\| G...	195.0	[0..1]	[209..1]
CREG1 - cellular repressor of E1A-stimulated genes 1 gi\|123995269, gi... - gi\|208965960\|dbj\|BAG72994.1\| cellular repressor of E1A-stimulated genes 1 [synthetic construct], gi\|...	193.0	[0..18]	[210..26]
gi\|114560951 - gi\|114560951\|ref\|XP_001157266.1\| PREDICTED: similar to cellular repressor of E1A-stimulated genes CR...	192.0	[0..18]	[210..141]
gi\|109019411 - gi\|109019411\|ref\|XP_001089325.1\| PREDICTED: similar to cellular repressor of E1A-stimulated genes [M...	188.0	[0..18]	[210..26]

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Predicted Domain #1

Region A:
Residues: [1-211]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTFHSLLFA LILALVSLDP SSGYSRRKDE RIIREYKREQ ELNHAKIARD LVHRANWAAV  60
   61 GSLSTNERVK GYPMVNIISI DDSDANNRST GRIRFLLTDL DFTGPDWQKD NKVTLLFSDE 120
  121 QTLRCKEGGK DPMEPTCARS MISGQVKKMD PSDKSYQPSL DAYVRRHPAA INWVKAHNFY 180
  181 LCELEISNIF VLDFYGGPHK VSASDYYAVS N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.69897
Match:	1xhnA
Description:	The crystal structure of Cellular Repressor of E1A-stimulated Genes (CREG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.31887334511829	bayes_pls_golite062009
transcription repressor activity	1.64863812936899	bayes_pls_golite062009
binding	1.60534132207804	bayes_pls_golite062009
catalytic activity	0.660906721832294	bayes_pls_golite062009
transcription factor binding	0.463016643940605	bayes_pls_golite062009
protein binding	0.222179736788716	bayes_pls_golite062009
transcription corepressor activity	0.00754193540843673	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: