YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213622196
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E98-2068
Length:	156 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213622196.

Description	E-value	Query Range	Subject Range
gi\|37678650, gi\|... - gi\|37678650\|ref\|NP_933259.1\| arginine repressor [Vibrio vulnificus YJ016], gi\|37197390\|dbj\|BAC93230....	2.0E-51	[1..153]	[55..207]
sp\|B7UJW9\|ARGR_ECO27 - Arginine repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=argR PE=3 SV=1 ARGR_ECOUT - Arginine repressor OS=Escherichia coli (strain UTI89 / UPEC) GN=argR PE=3 SV=1 gi\|190905882, gi... - gi\|75237908\|ref\|ZP_00721919.1\| COG1438: Arginine repressor [Escherichia coli F11], gi\|191173832\|ref\|... ARGR_ECOL6 - Arginine repressor OS=Escherichia coli O6 GN=argR PE=3 SV=1 ARGR_ECOL5 - Arginine repressor OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=argR PE=3 SV=1 gi\|109389944, gi... - gi\|109389984\|gb\|ABG29721.1\| arginine biosynthesis repressor [Escherichia coli], gi\|109389982\|gb\|ABG2... gi\|237706016, gi... - gi\|237706016\|ref\|ZP_04536497.1\| arginine repressor [Escherichia sp. 3_2_53FAA], gi\|226899056\|gb\|EEH8... gi\|227835348, gi... - gi\|227887952\|ref\|ZP_04005757.1\| arginine repressor [Escherichia coli 83972], gi\|227835348\|gb\|EEJ4581... ARGR_ECO27 - Arginine repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=argR PE=3 SV=1 ARGR_ECOL6 - Arginine repressor OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=argR PE=3 SV=1 ARGR_ECOK1 - Arginine repressor OS=Escherichia coli O1:K1 / APEC GN=argR PE=3 SV=1 ARGR_ECO45 - Arginine repressor OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=argR PE=3 SV=1 ARGR_ECO81 - Arginine repressor OS=Escherichia coli O81 (strain ED1a) GN=argR PE=3 SV=1	3.0E-51	[1..156]	[1..156]
gi\|168754219, gi... - gi\|189358675\|gb\|EDU77094.1\| arginine repressor [Escherichia coli O157:H7 str. EC4401], gi\|168754219\|... gi\|188013942, gi... - gi\|188013942\|gb\|EDU52064.1\| arginine repressor [Escherichia coli O157:H7 str. EC4113], gi\|168752150\|... gi\|168769093, gi... - gi\|189361819\|gb\|EDU80238.1\| arginine repressor [Escherichia coli O157:H7 str. EC4486], gi\|168769093\|... gi\|168763774, gi... - gi\|189366124\|gb\|EDU84540.1\| arginine repressor [Escherichia coli O157:H7 str. EC4501], gi\|168763774\|... gi\|168781381, gi... - gi\|189000968\|gb\|EDU69954.1\| arginine repressor [Escherichia coli O157:H7 str. EC4076], gi\|168781381\|... gi\|187767166, gi... - gi\|187767166\|gb\|EDU31010.1\| arginine repressor [Escherichia coli O157:H7 str. EC4196], gi\|168777632\|... ARGR_ECO5E - Arginine repressor OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=argR PE=3 SV=1 gi\|208739355, gi... - gi\|208819232\|ref\|ZP_03259552.1\| arginine repressor [Escherichia coli O157:H7 str. EC4042], gi\|208739... gi\|217326689, gi... - gi\|217326689\|ref\|ZP_03442772.1\| arginine repressor [Escherichia coli O157:H7 str. TW14588], gi\|21731... ARGR_ECOSE - Arginine repressor OS=Escherichia coli (strain SE11) GN=argR PE=3 SV=1 ARGR_ECO55 - Arginine repressor OS=Escherichia coli (strain 55989 / EAEC) GN=argR PE=3 SV=1 ARGR_ECO8A - Arginine repressor OS=Escherichia coli O8 (strain IAI1) GN=argR PE=3 SV=1 ARGR_ECOLU - Arginine repressor OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=argR PE=3 SV=1 ARGR_ECO7I - Arginine repressor OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=argR PE=3 SV=1 gi\|189376818, gi... - gi\|189376818\|gb\|EDU95234.1\| arginine repressor [Escherichia coli O157:H7 str. EC508], gi\|168800950\|r... gi\|189374120, gi... - gi\|189374120\|gb\|EDU92536.1\| arginine repressor [Escherichia coli O157:H7 str. EC869], gi\|168786123\|r... ARGR_ECOSM - Arginine repressor OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=argR PE=3 SV=1 ARGR_ECODH - Arginine repressor OS=Escherichia coli (strain K12 / DH10B) GN=argR PE=3 SV=1 gi\|195939435 - gi\|195939435\|ref\|ZP_03084817.1\| arginine repressor [Escherichia coli O157:H7 str. EC4024] gi\|194434887, gi... - gi\|194434887\|ref\|ZP_03067133.1\| arginine repressor [Shigella dysenteriae 1012], gi\|194416863\|gb\|EDX3... gi\|208812236, gi... - gi\|208812236\|ref\|ZP_03253565.1\| arginine repressor [Escherichia coli O157:H7 str. EC4045], gi\|208733... gi\|208729469, gi... - gi\|208809668\|ref\|ZP_03252005.1\| arginine repressor [Escherichia coli O157:H7 str. EC4206], gi\|208729... EG10070 - l-arginine-responsive arginine metabolism regulon transcriptional regulator / Repressor of Arg regul... ARGR_SHIFL - Arginine repressor OS=Shigella flexneri GN=argR PE=3 SV=1 gi\|24053713, gi\|... - gi\|24114524\|ref\|NP_709034.1\| arginine repressor [Shigella flexneri 2a str. 301], gi\|24053713\|gb\|AAN4... gi\|30042828, gi\|... - gi\|30064569\|ref\|NP_838740.1\| arginine repressor [Shigella flexneri 2a str. 2457T], gi\|30042828\|gb\|AA... gi\|124500534, gi... - gi\|124528511\|ref\|ZP_01699800.1\| arginine repressor, ArgR [Escherichia coli B], gi\|124500534\|gb\|EAY48... ARGR_ECO57 - Arginine repressor OS=Escherichia coli O157:H7 GN=argR PE=3 SV=1 EG10070 - l-arginine-responsive arginine metabolism regulon transcriptional regulator / Repressor of Arg regul... gi\|15803771, gi\|... - gi\|15803771\|ref\|NP_289805.1\| arginine repressor [Escherichia coli O157:H7 EDL933], gi\|12517858\|gb\|AA... gi\|89109999, gi\|... - gi\|89109999\|ref\|AP_003779.1\| DNA-binding transcriptional dual regulator, L-arginine-binding [Escheri... ARGR_SHIDS - Arginine repressor OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=argR PE=3 SV=1 ARGR_ECOLC - Arginine repressor OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=argR PE=3 SV=1 ARGR_SHIBS - Arginine repressor OS=Shigella boydii serotype 4 (strain Sb227) GN=argR PE=3 SV=1 ARGR_ECOBW - Arginine repressor OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=argR PE=3 SV=1 gi\|226840021, gi... - gi\|254038397\|ref\|ZP_04872455.1\| arginine repressor [Escherichia sp. 1_1_43], gi\|226840021\|gb\|EEH7204... gi\|75209674, gi\|... - gi\|75209674\|ref\|ZP_00709886.1\| COG1438: Arginine repressor [Escherichia coli B171], gi\|194429133\|ref... gi\|254594580, gi... - gi\|254795180\|ref\|YP_003080017.1\| DNA-binding transcriptional regulatory protein [Escherichia coli O1... gi\|190901785, gi... - gi\|75228637\|ref\|ZP_00715262.1\| COG1438: Arginine repressor [Escherichia coli B7A], gi\|191168177\|ref\|... ARGR_ECO24 - Arginine repressor OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=argR PE=3 SV=1 ARGR_ECOHS - Arginine repressor OS=Escherichia coli O9:H4 (strain HS) GN=argR PE=3 SV=1 gi\|75511867, gi\|... - gi\|75511867\|ref\|ZP_00734479.1\| COG1438: Arginine repressor [Escherichia coli 53638], gi\|188494541\|re... gi\|13363583, gi\|... - gi\|15833364\|ref\|NP_312137.1\| arginine repressor [Escherichia coli O157:H7 str. Sakai], gi\|13363583\|d... ARGR_SHISS - Arginine repressor OS=Shigella sonnei (strain Ss046) GN=argR PE=3 SV=1 ARGR_SHIF8 - Arginine repressor OS=Shigella flexneri serotype 5b (strain 8401) GN=argR PE=3 SV=1 gi\|75234855, gi\|... - gi\|75234855\|ref\|ZP_00719146.1\| COG1438: Arginine repressor [Escherichia coli E110019], gi\|193070310\|... gi\|192926985, gi... - gi\|75256607\|ref\|ZP_00728237.1\| COG1438: Arginine repressor [Escherichia coli E22], gi\|193065344\|ref\|... gi\|194439167, gi... - gi\|83585392\|ref\|ZP_00924038.1\| COG1438: Arginine repressor [Escherichia coli 101-1], gi\|194439167\|re... ARGR_ECOLI - Arginine repressor - Escherichia coli ARGR_SHIB3 - Arginine repressor OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=argR PE=3 SV=1	5.0E-51	[1..156]	[1..156]
ARGR_VIBCB - Arginine repressor OS=Vibrio campbellii (strain ATCC BAA-1116 / BB120) GN=argR PE=3 SV=1 gi\|148869250, gi... - gi\|153834402\|ref\|ZP_01987069.1\| arginine repressor [Vibrio harveyi HY01], gi\|148869250\|gb\|EDL68272.1... ARGR_VIBPA - Arginine repressor OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=argR PE=3 SV=1 ARGR_VIBPA - Arginine repressor OS=Vibrio parahaemolyticus GN=argR PE=3 SV=1	6.0E-51	[1..153]	[1..153]
ARGR_PECAS - Arginine repressor OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN=argR PE=3 SV=... ARGR_ERWCT - Arginine repressor OS=Erwinia carotovora subsp. atroseptica GN=argR PE=3 SV=1	1.0E-50	[1..156]	[1..156]
ARGR_VIBVY - Arginine repressor OS=Vibrio vulnificus (strain YJ016) GN=argR PE=1 SV=1 ARGR_VIBVU - Arginine repressor OS=Vibrio vulnificus (strain CMCP6) GN=argR PE=3 SV=1 ARGR_VIBVU - Arginine repressor OS=Vibrio vulnificus GN=argR PE=3 SV=1	2.0E-50	[1..153]	[1..153]
gi\|116184028, gi... - gi\|75854581\|ref\|ZP_00762267.1\| COG1438: Arginine repressor [Vibrio sp. Ex25], gi\|116184028\|ref\|ZP_01...	3.0E-50	[1..153]	[1..153]
gi\|109389834 - gi\|109389834\|gb\|ABG29646.1\| arginine biosynthesis repressor [Escherichia coli] gi\|253975075, gi... - gi\|254163174\|ref\|YP_003046282.1\| arginine repressor [Escherichia coli B str. REL606], gi\|253975075\|g... gi\|242378775, gi... - gi\|251786502\|ref\|YP_003000806.1\| hypothetical protein B21_03048 [Escherichia coli BL21], gi\|24237877... gi\|253979231, gi... - gi\|254289924\|ref\|YP_003055672.1\| arginine repressor [Escherichia coli BL21(DE3)], gi\|253979231\|gb\|AC...	4.0E-50	[1..156]	[1..156]
gi\|84394040, gi\|... - gi\|84394040\|ref\|ZP_00992777.1\| arginine repressor [Vibrio splendidus 12B01], gi\|84375326\|gb\|EAP92236... gi\|86147823, gi\|... - gi\|86147823\|ref\|ZP_01066129.1\| arginine repressor [Vibrio sp. MED222], gi\|85834350\|gb\|EAQ52502.1\| ar... ARGR_VIBTL - Arginine repressor OS=Vibrio tasmaniensis (strain LGP32) GN=argR PE=3 SV=1	5.0E-50	[1..153]	[1..153]
gi\|28805307 - gi\|28805307\|dbj\|BAC58587.1\| arginine repressor [Vibrio parahaemolyticus RIMD 2210633] gi\|28805307, gi\|... - gi\|28897098\|ref\|NP_796703.1\| arginine repressor [Vibrio parahaemolyticus RIMD 2210633], gi\|28805307\|...	7.0E-50	[1..153]	[18..170]

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Predicted Domain #1

Region A:
Residues: [1-76]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSSAKQEEL VRAFKALLKE EKFSSQGEIV LALQDQGFEN INQSKVSRML TKFGAVRTRN  60
   61 AKMEMVYCLP AELGVP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.39794
Match:	1aoyA
Description:	N-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR NMR, 23 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.98990675336286	bayes_pls_golite062009
DNA binding	3.4273272886116	bayes_pls_golite062009
nucleic acid binding	3.38054693035398	bayes_pls_golite062009
transcription factor activity	2.80110428028438	bayes_pls_golite062009
binding	2.18911933843505	bayes_pls_golite062009
transcription activator activity	0.53294679084865	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
transcription repressor activity	0.513853050429619	bayes_pls_golite062009
protein binding	0.035220363090062	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [77-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTSSPLKNLV LDIDYNDAVV VIHTSPGAAQ LIARLLDSLG KAEGILGTIA GDDTIFTTPA  60
   61 SGFSVRDLYE AILELFEQEL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.522879
Match:	1xxaA
Description:	C-terminal domain of arginine repressor
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: