YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|190407168
Organism:	Saccharomyces cerevisiae RM11-1a
Length:	802 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190407168.

Description	E-value	Query Range	Subject Range
GART - phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylami...	0.0	[3..798]	[4..781]
gi\|18858729, gi\|... - gi\|8050811\|gb\|AAF71749.1\| phosphoribosylglycinamide formyltransferase; Gart [Danio rerio], gi\|188587...	0.0	[3..800]	[4..783]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[3..798]	[4..781]
gi\|691792, gi\|68... - gi\|691792\|gb\|AAC53251.1\| glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthet...	0.0	[3..798]	[4..781]
PUR2_CHICK - Trifunctional purine biosynthetic protein adenosine-3 OS=Gallus gallus GN=GART PE=2 SV=1	0.0	[3..798]	[4..779]
gi\|9957024 - gi\|9957024\|gb\|AAG09178.1\| purine biosynthetic pathway protein ADE5,7 [Kluyveromyces lactis]	0.0	[3..802]	[4..792]
PUR2_YEAST - Bifunctional purine biosynthetic protein ADE5,7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2... gi\|151943584 - gi\|151943584\|gb\|EDN61894.1\| aminoimidazole ribotide synthetase [Saccharomyces cerevisiae YJM789] ADE5,7 - Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole... gi\|190407168 - gi\|190407168\|gb\|EDV10435.1\| aminoimidazole ribotide synthetase [Saccharomyces cerevisiae RM11-1a]	0.0	[1..802]	[1..802]
PUR2_YARLI - Bifunctional purine biosynthetic protein ADE1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=AD... PUR2_YARLI - Bifunctional purine biosynthetic protein ADE1 OS=Yarrowia lipolytica GN=ADE1 PE=3 SV=1	0.0	[3..802]	[4..788]
gi\|4028156 - gi\|4028156\|gb\|AAC96120.1\| glycinamide ribonucleotide transformylase [Takifugu rubripes]	0.0	[3..799]	[4..782]
ade1 - phosphoribosylamine-glycine ligase PUR2_SCHPO - Bifunctional purine biosynthetic protein ADE1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)...	0.0	[5..801]	[7..785]

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Predicted Domain #1

Region A:
Residues: [1-98]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNILVLGNG AREHVLVTKL AQSPTVGKIY VAPGNGGTAT MDPSRVINWD ITPDVANFAR  60
   61 LQSMAVEHKI NLVVPGPELP LVNGITSVFH SVGIPVFG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1021.0
Match:	1gsoA_
Description:	Glycinamide ribonucleotide synthetase (GAR-syn), C-domain; Glycinamide ribonucleotide synthetase (GAR-syn), N-domain; Glycinamide ribonucleotide synthetase (GAR-syn), domain 2
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [99-126]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSVKAAQLEA SKAFSKRFMS KHNIPTAS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [197-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEGDEISLLT IVDGYSHFNL PVAQ

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [241-342]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APAPVATPSL LKTIDSQIVK PTIDGMRRDG MPFVGVLFTG MILVKDSKTN QLVPEVLEYN  60
   61 VRFGDPETQA VLSLLDDQTD LAQVFLAAAE HRLDSVNIGI DD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1021.0
Match:	1gsoA_
Description:	Glycinamide ribonucleotide synthetase (GAR-syn), C-domain; Glycinamide ribonucleotide synthetase (GAR-syn), N-domain; Glycinamide ribonucleotide synthetase (GAR-syn), domain 2
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [127-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDVFTNPEEA ISFLQAHTDK AFVIKADGIA AGKGVIIPSS IDESVQAIKD IMVTKQFGEE  60
   61 AGKQVVIEQF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [221-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DHKRIFDGDK GLNTGGMGAY

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [343-445]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRSAVTVVVA AGGYPESYAK GDKITLDTDK LPPHTQIFQA GTKYDSATDS LLTNGGRVLS  60
   61 VTSTAQDLRT AVDTVYEAVK CVHFQNSYYR KDIAYRAFQN SES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1021.0
Match:	1gsoA_
Description:	Glycinamide ribonucleotide synthetase (GAR-syn), C-domain; Glycinamide ribonucleotide synthetase (GAR-syn), N-domain; Glycinamide ribonucleotide synthetase (GAR-syn), domain 2
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [446-511]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKVAITYADS GVSVDNGNNL VQTIKEMVRS TRRPGADSDI GGFGGLFDLA QAGFRQNEDT  60
   61 LLVGAT

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.0
Match:	1cliA
Description:	Aminoimidazole ribonucleotide synthetase (PurM) N-terminal domain; Aminoimidazole ribonucleotide synthetase (PurM) C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [512-615]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGVGTKLIIA QETGIHNTVG IDLVAMNVND LVVQGAEPLF FLDYFATGAL DIQVASDFVS  60
   61 GVANGCIQSG CALVGGETSE MPGMYPPGHY DTNGTAVGAV LRQD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	982.0
Match:	1cliA_
Description:	Aminoimidazole ribonucleotide synthetase (PurM) N-terminal domain; Aminoimidazole ribonucleotide synthetase (PurM) C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [616-635]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILPKINEMAA GDVLLGLASS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [682-802]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLLPSIRQRL LLGLAHITGG GLVENIPRAI PDHLQARVDM STWEVPRVFK WFGQAGNVPH  60
   61 DDILRTFNMG VGMVLIVKRE NVKAVCDSLT EEGEIIWELG SLQERPKDAP GCVIENGTKL 120
  121 Y

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	982.0
Match:	1cliA_
Description:	Aminoimidazole ribonucleotide synthetase (PurM) N-terminal domain; Aminoimidazole ribonucleotide synthetase (PurM) C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #7

Region A:
Residues: [636-681]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVHSNGFSLV RKIIQHVALP WDAPCPWDES KTLGEGILEP TKIYVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	982.0
Match:	1cliA_
Description:	Aminoimidazole ribonucleotide synthetase (PurM) N-terminal domain; Aminoimidazole ribonucleotide synthetase (PurM) C-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits