YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|190405069
Organism:	Saccharomyces cerevisiae RM11-1a
Length:	238 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190405069.

Description	E-value	Query Range	Subject Range
RAD59 - Protein involved in the repair of double-strand breaks in DNA during vegetative growth via recombina... gi\|190405069 - gi\|190405069\|gb\|EDV08336.1\| DNA repair protein RAD59 [Saccharomyces cerevisiae RM11-1a] RAD59_YEAST - DNA repair protein RAD59 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD59 PE=1 SV=1	4.0E-99	[1..238]	[1..238]
RAD59_KLULA, RA5... - DNA repair protein RAD59 OS=Kluyveromyces lactis GN=RAD59 PE=3 SV=1, (Q9HEU2) DNA repair protein RAD... RAD59_KLULA - DNA repair protein RAD59 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 126...	1.0E-76	[9..213]	[5..203]
gi\|6755280, gi\|1... - gi\|6755280\|ref\|NP_035366.1\| RAD52 homolog [Mus musculus], gi\|458458\|gb\|AAA75441.1\| homology to Swiss...	2.0E-70	[41..226]	[30..197]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-70	[41..226]	[30..197]
gi\|6716781 - gi\|6716781\|gb\|AAF26740.1\|AF220495_1 Rad52 recombination protein [Cricetulus griseus]	1.0E-69	[41..226]	[30..197]
RAD22_SCHPO - DNA repair and recombination protein rad22 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN... rad22 - DNA repair protein Rad22	4.0E-67	[41..230]	[19..198]

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Predicted Domain #1

Region A:
Residues: [1-173]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIQAKPSSS ISYDSTTYGT APGLDIKEFQ IIEDWNGRPA SAWSVQRIGL LQSKIERYTY  60
   61 NIYHNNKYGK HNLSKLIPGH ALIQFANETF GYDGWRMDVI DVEARECQPF TAVNNGENTN 120
  121 TSEVKYTVVA EAQVKVTLKD GTNTQCGGLG RITLSSRGEC YNRSKKEAVG DAL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	3.09705138687537	bayes_pls_golite062009
nucleic acid binding	2.62582371207063	bayes_pls_golite062009
RNA binding	1.51047378734681	bayes_pls_golite062009
protein binding	1.33336414936007	bayes_pls_golite062009
DNA binding	1.09648705416581	bayes_pls_golite062009
transcription regulator activity	0.558060375765317	bayes_pls_golite062009
double-stranded RNA binding	0.33006862628358	bayes_pls_golite062009
structure-specific DNA binding	0.109630981204183	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [174-238]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKALLSFEKI ILDYETKITN NYYVDGLYGS KKIKNEANTN YNLLSATNSK PTFIKLEDAK  60
   61 GTHIK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.825	0.036	DNA strand annealing activity	d.50.1	dsRNA-binding domain-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: