YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213583599
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E98-0664
Length:	322 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213583599.

Description	E-value	Query Range	Subject Range
ASTE_SALCH - Succinylglutamate desuccinylase OS=Salmonella choleraesuis (strain SC-B67) GN=astE PE=3 SV=1 ASTE_SALCH - Succinylglutamate desuccinylase OS=Salmonella choleraesuis GN=astE PE=3 SV=1 ASTE_SALCH - Succinylglutamate desuccinylase OS=Salmonella choleraesuis GN=astE PE=3 SV=1	8.0E-94	[1..322]	[1..322]
ASTE_SALPK - Succinylglutamate desuccinylase OS=Salmonella paratyphi A (strain AKU_12601) GN=astE PE=3 SV=1 ASTE_SALPA - Succinylglutamate desuccinylase OS=Salmonella paratyphi A GN=astE PE=3 SV=1 ASTE_SALPA - Succinylglutamate desuccinylase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=astE PE=3 S...	2.0E-92	[1..322]	[1..322]
ASTE_SALTY - Succinylglutamate desuccinylase OS=Salmonella typhimurium GN=astE PE=2 SV=1 ASTE_SALTY - Succinylglutamate desuccinylase OS=Salmonella typhimurium GN=astE PE=2 SV=1 gi\|197262079, gi... - gi\|197262079\|ref\|ZP_03162153.1\| succinylglutamate desuccinylase [Salmonella enterica subsp. enterica... gi\|205329723, gi... - gi\|205329723\|gb\|EDZ16487.1\| succinylglutamate desuccinylase [Salmonella enterica subsp. enterica ser... ASTE_SALTY - Succinylglutamate desuccinylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=a... lcl\|NC_016856.1_... - [gene=astE] [protein=succinylglutamate desuccinylase] [protein_id=YP_005237161.1] [location=1397229....	6.0E-92	[1..322]	[1..322]
gi\|194422573, gi... - gi\|83586043\|ref\|ZP_00924681.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli 101-1], gi... ASTE_ECODH - Succinylglutamate desuccinylase OS=Escherichia coli (strain K12 / DH10B) GN=astE PE=3 SV=1 ASTE_SHIB3 - Succinylglutamate desuccinylase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=astE ... ASTE_ECOHS - Succinylglutamate desuccinylase OS=Escherichia coli O9:H4 (strain HS) GN=astE PE=3 SV=1 gi\|192957791, gi... - gi\|75236787\|ref\|ZP_00720858.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli E110019], ... ASTE_ECO8A - Succinylglutamate desuccinylase OS=Escherichia coli O8 (strain IAI1) GN=astE PE=3 SV=1 gi\|188491828, gi... - gi\|75513760\|ref\|ZP_00736136.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli 53638], gi... ASTE_ECOSE - Succinylglutamate desuccinylase OS=Escherichia coli (strain SE11) GN=astE PE=3 SV=1 ASTE_ECOLI - Succinylglutamate desuccinylase (EC 3.5.1.96) - Escherichia coli ASTE_ECOBW - Succinylglutamate desuccinylase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=astE PE=3 SV=1 gi\|242377465, gi... - gi\|251785192\|ref\|YP_002999496.1\| hypothetical protein B21_01701 [Escherichia coli BL21], gi\|24237746... gi\|253773302, gi... - gi\|254288591\|ref\|YP_003054339.1\| succinylglutamate desuccinylase [Escherichia coli BL21(DE3)], gi\|25... gi\|254161803, gi... - gi\|254161803\|ref\|YP_003044911.1\| succinylglutamate desuccinylase [Escherichia coli B str. REL606], g... gi\|89108583, gi\|... - gi\|89108583\|ref\|AP_002363.1\| succinylglutamate desuccinylase [Escherichia coli str. K-12 substr. W31... EG13995 - succinylglutamate desuccinylase / Succinylglutamate desuccinylase, arginine catabolism EG13995 - succinylglutamate desuccinylase / Succinylglutamate desuccinylase, arginine catabolism	6.0E-88	[1..321]	[1..321]
ASTE_SHIF8 - Succinylglutamate desuccinylase OS=Shigella flexneri serotype 5b (strain 8401) GN=astE PE=3 SV=1	7.0E-88	[1..321]	[1..321]
ASTE_SHIFL - Succinylglutamate desuccinylase OS=Shigella flexneri GN=astE PE=3 SV=1 ASTE_SHIBS - Succinylglutamate desuccinylase OS=Shigella boydii serotype 4 (strain Sb227) GN=astE PE=3 SV=1 gi\|30062989, gi\|... - gi\|30062989\|ref\|NP_837160.1\| succinylglutamate desuccinylase [Shigella flexneri 2a str. 2457T], gi\|3...	8.0E-88	[1..321]	[1..321]
ASTE_ECOUT - Succinylglutamate desuccinylase OS=Escherichia coli (strain UTI89 / UPEC) GN=astE PE=3 SV=1 gi\|227885831, gi... - gi\|227885831\|ref\|ZP_04003636.1\| succinylglutamate desuccinylase [Escherichia coli 83972], gi\|2278374... gi\|237705694, gi... - gi\|237705694\|ref\|ZP_04536175.1\| succinylglutamate desuccinylase [Escherichia sp. 3_2_53FAA], gi\|2269... ASTE_ECO81 - Succinylglutamate desuccinylase OS=Escherichia coli O81 (strain ED1a) GN=astE PE=3 SV=1 ASTE_ECO45 - Succinylglutamate desuccinylase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=astE PE=3 SV=1 ASTE_ECOK1 - Succinylglutamate desuccinylase OS=Escherichia coli O1:K1 / APEC GN=astE PE=3 SV=1 ASTE_ECOL6 - Succinylglutamate desuccinylase OS=Escherichia coli O6 GN=astE PE=3 SV=1 ASTE_ECOL6 - Succinylglutamate desuccinylase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=as...	1.0E-87	[1..321]	[1..321]
gi\|75256146, gi\|... - gi\|75256146\|ref\|ZP_00727842.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli E22], gi\|1... gi\|75210231, gi\|... - gi\|75210231\|ref\|ZP_00710399.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli B171], gi\|... ASTE_ECO24 - Succinylglutamate desuccinylase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=astE PE=3 SV...	1.0E-87	[1..321]	[1..321]
gi\|191169571, gi... - gi\|75227071\|ref\|ZP_00713895.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli B7A], gi\|1...	1.0E-87	[1..321]	[1..321]
gi\|15831704, gi\|... - gi\|15831704\|ref\|NP_310477.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. Sakai], ... gi\|189360619, gi... - gi\|189360619\|gb\|EDU79038.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4486], ... gi\|168762187, gi... - gi\|189367516\|gb\|EDU85932.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4501], ... gi\|189356184, gi... - gi\|189356184\|gb\|EDU74603.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4401], ... gi\|188016256, gi... - gi\|188016256\|gb\|EDU54378.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4113], ... gi\|189377555, gi... - gi\|189377555\|gb\|EDU95971.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC508], g... gi\|189371974, gi... - gi\|189371974\|gb\|EDU90390.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC869], g... gi\|168782164, gi... - gi\|189000320\|gb\|EDU69306.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4076], ... gi\|168774952, gi... - gi\|187769385\|gb\|EDU33229.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4196], ... ASTE_ECO57 - Succinylglutamate desuccinylase OS=Escherichia coli O157:H7 GN=astE PE=3 SV=1 gi\|254592762, gi... - gi\|254793362\|ref\|YP_003078199.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. TW14... gi\|12515763, gi\|... - gi\|15802155\|ref\|NP_288177.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 EDL933], gi\|1... gi\|209768602, gi... - pir\|\|F85783 hypothetical protein ydjS [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|208740258, gi... - gi\|208820135\|ref\|ZP_03260455.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC404... gi\|208731176, gi... - gi\|208816833\|ref\|ZP_03257953.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC404... gi\|208725098, gi... - gi\|208810582\|ref\|ZP_03252458.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC420... gi\|195937428 - gi\|195937428\|ref\|ZP_03082810.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC402... gi\|217318041, gi... - gi\|217328694\|ref\|ZP_03444775.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. TW145... ASTE_ECO5E - Succinylglutamate desuccinylase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=astE PE=3 SV=1	2.0E-87	[1..321]	[1..321]

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Predicted Domain #1

Region A:
Residues: [1-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNFLALTLS GTTPRVTQGK GAGFRWRWLG HGLLELTPDA PVDRALILSA GIHGNETAPV  60
   61 EMLDKLLSAL YSGSLTLTWR VLVVLGNPQA LAAGIRYCHS DMNRMFGGRW QSFAESDETR 120
  121 RARELELSLE TFFSSGQARV RWHLDLHTAI RGSHHLRFGV LPQRDRPWEA DFLAWLGAAG 180
  181 LEALVFHQAP GGTFTHFSSE HFGALSCTLE LGKALPFGQN DLTQFSVTSQ ALSALLSGVE 240
  241 TSTSFSPPLR YRVVSQITRH SDKFALYMDA QTLNFTAFAK GTLLAEEGDK RVTVTHDVEY 300
  301 VLFPNSSVAC GLRAGLMLER LP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	89.154902
Match:	1yw6A
Description:	Crystal Structure of Succinylglutamate Desuccinylase from Escherichia coli, Northeast Structural Genomics Target ET72.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.7824202462173	bayes_pls_golite062009
catalytic activity	1.76936806579991	bayes_pls_golite062009
peptidase activity	1.69812537802871	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	1.41029347724469	bayes_pls_golite062009
exopeptidase activity	0.82896398764377	bayes_pls_golite062009
succinylglutamate desuccinylase activity	0.46025450502966	bayes_pls_golite062009
carboxypeptidase activity	0.215630276604929	bayes_pls_golite062009
N-formylglutamate deformylase activity	0.17769913093601	bayes_pls_golite062009
metallopeptidase activity	0.1586028474273	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: