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View Structure Prediction Details

Protein: gi|197939343, gi...
Organism: Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853
Length: 241 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|197939343, gi....

Description E-value Query
Range
Subject
Range
PHOU_ENTCL - Phosphate-specific transport system accessory protein PhoU OS=Enterobacter cloacae GN=phoU PE=3 SV=1
3.0E-59 [1..241] [1..241]
gi|209158028, gi... - gi|209396628|ref|YP_002273247.1| phosphate transport system regulatory protein PhoU [Escherichia col...
gi|217321734, gi... - gi|217325513|ref|ZP_03441597.1| phosphate transport system regulatory protein PhoU [Escherichia coli...
gi|254595122, gi... - gi|254795722|ref|YP_003080559.1| negative regulator of PhoR/PhoB two-component regulator [Escherichi...
gi|218702570, gi... - gi|218702570|ref|YP_002410199.1| transcriptional regulator PhoU [Escherichia coli IAI39], gi|2183725...
gi|218707366, gi... - gi|218707366|ref|YP_002414885.1| transcriptional regulator PhoU [Escherichia coli UMN026], gi|218434...
gi|209753972, gi... - pir||D91211 hypothetical protein ECs4660 [imported] - Escherichia coli (strain O157:H7, substrain R...
gi|189002565, gi... - gi|189002565|gb|EDU71551.1| phosphate transport system regulatory protein PhoU [Escherichia coli O15...
gi|189373287, gi... - gi|189373287|gb|EDU91703.1| phosphate transport system regulatory protein PhoU [Escherichia coli O15...
gi|12518568, gi|... - gi|15804317|ref|NP_290356.1| transcriptional regulator PhoU [Escherichia coli O157:H7 EDL933], gi|12...
gi|168798763, gi... - gi|189378751|gb|EDU97167.1| phosphate transport system regulatory protein PhoU [Escherichia coli O15...
gi|15833914, gi|... - gi|15833914|ref|NP_312687.1| PhoU [Escherichia coli O157:H7], gi|13364135|dbj|BAB38083.1| phosphate ...
gi|170683229, gi... - gi|170683229|ref|YP_001746050.1| phosphate transport system regulatory protein PhoU [Escherichia col...
gi|15833914, gi|... - gi|15833914|ref|NP_312687.1| transcriptional regulator PhoU [Escherichia coli O157:H7 str. Sakai], g...
gi|195936346 - gi|195936346|ref|ZP_03081728.1| transcriptional regulator PhoU [Escherichia coli O157:H7 str. EC4024...
gi|208728055, gi... - gi|208808254|ref|ZP_03250591.1| phosphate transport system regulatory protein PhoU [Escherichia coli...
gi|208735078, gi... - gi|208813801|ref|ZP_03255130.1| phosphate transport system regulatory protein PhoU [Escherichia coli...
gi|208738876, gi... - gi|208818753|ref|ZP_03259073.1| phosphate transport system regulatory protein PhoU [Escherichia coli...
gi|168748556, gi... - gi|188016904|gb|EDU55026.1| phosphate transport system regulatory protein PhoU [Escherichia coli O15...
gi|194431306, gi... - gi|83571513|ref|ZP_00922953.1| COG0704: Phosphate uptake regulator [Shigella dysenteriae 1012], gi|1...
gi|189358849, gi... - gi|189358849|gb|EDU77268.1| phosphate transport system regulatory protein PhoU [Escherichia coli O15...
gi|81243234, gi|... - gi|82779086|ref|YP_405435.1| transcriptional regulator PhoU [Shigella dysenteriae Sd197], gi|8124323...
gi|168759915, gi... - gi|189369801|gb|EDU88217.1| phosphate transport system regulatory protein PhoU [Escherichia coli O15...
gi|168766215, gi... - gi|189364683|gb|EDU83102.1| phosphate transport system regulatory protein PhoU [Escherichia coli O15...
gi|168772237, gi... - gi|187771433|gb|EDU35277.1| phosphate transport system regulatory protein PhoU [Escherichia coli O15...
2.0E-58 [1..241] [1..241]
gi|166205645, gi... - gi|166213347|ref|ZP_02239382.1| phosphate transport system regulatory protein PhoU [Yersinia pestis ...
gi|167401532, gi... - gi|167401532|ref|ZP_02307026.1| phosphate transport system regulatory protein PhoU [Yersinia pestis ...
gi|167425542, gi... - gi|167425542|ref|ZP_02317295.1| phosphate transport system regulatory protein PhoU [Yersinia pestis ...
gi|145601160, gi... - gi|145601160|ref|YP_001165236.1| transcriptional regulator PhoU [Yersinia pestis Pestoides F], gi|14...
gi|186897478, gi... - gi|186897478|ref|YP_001874590.1| transcriptional regulator PhoU [Yersinia pseudotuberculosis PB1/+],...
gi|108782061, gi... - gi|108810148|ref|YP_654064.1| transcriptional regulator PhoU [Yersinia pestis Antiqua], gi|108782061...
Q663R6|Q663R6_YERPS - Phosphate transport regulatory protein - Yersinia pseudotuberculosis
gi|51591525, gi|... - gi|51598243|ref|YP_072434.1| transcriptional regulator PhoU [Yersinia pseudotuberculosis IP 32953], ...
gi|108814130, gi... - gi|229904671|ref|ZP_04519782.1| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe...
gi|45443743, gi|... - gi|45443743|ref|NP_995282.1| transcriptional regulator PhoU [Yersinia pestis biovar Microtus str. 91...
gi|22127995, gi|... - gi|22127995|ref|NP_671418.1| transcriptional regulator PhoU [Yersinia pestis KIM], gi|21961142|gb|AA...
gi|162419718, gi... - gi|77634101|ref|ZP_00796209.1| COG0704: Phosphate uptake regulator [Yersinia pestis Angola], gi|1624...
gi|152962140, gi... - gi|77630946|ref|ZP_00793532.1| COG0704: Phosphate uptake regulator [Yersinia pseudotuberculosis IP 3...
gi|229700221, gi... - gi|229896783|ref|ZP_04511946.1| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe...
3.0E-58 [1..240] [1..240]
gi|77977952, gi|... - gi|77977952|ref|ZP_00833389.1| COG0704: Phosphate uptake regulator [Yersinia intermedia ATCC 29909],...
4.0E-58 [1..240] [1..240]
gi|77961808, gi|... - gi|77961808|ref|ZP_00825638.1| COG0704: Phosphate uptake regulator [Yersinia mollaretii ATCC 43969],...
1.0E-57 [1..240] [1..240]
gi|15982002, gi|... - gi|218931089|ref|YP_002348964.1| transcriptional regulator PhoU [Yersinia pestis CO92], gi|16124221|...
gi|25300312 - pir||AE0499 probable phosphate transport system protein phoU [imported] - Yersinia pestis (strain CO...
gi|229839821, gi... - gi|229839821|ref|ZP_04459980.1| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe...
gi|229841906, gi... - gi|229841906|ref|ZP_04462062.1| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe...
gi|89104500, gi|... - gi|89104500|ref|ZP_01177041.1| COG0704: Phosphate uptake regulator [Yersinia pestis biovar Orientali...
gi|165991498, gi... - gi|166009576|ref|ZP_02230474.1| phosphate transport system regulatory protein PhoU [Yersinia pestis ...
gi|165926131, gi... - gi|165926131|ref|ZP_02221963.1| phosphate transport system regulatory protein PhoU [Yersinia pestis ...
gi|167468124 - gi|167468124|ref|ZP_02332828.1| transcriptional regulator PhoU [Yersinia pestis FV-1]
gi|166958252, gi... - gi|167422860|ref|ZP_02314613.1| phosphate transport system regulatory protein PhoU [Yersinia pestis ...
gi|150260953, gi... - gi|150260953|ref|ZP_01917681.1| putative phosphate transport system protein [Yersinia pestis CA88-41...
1.0E-57 [1..240] [1..240]
gi|238724196, gi... - gi|77973792|ref|ZP_00829337.1| COG0704: Phosphate uptake regulator [Yersinia frederiksenii ATCC 3364...
2.0E-57 [1..240] [1..240]
gi|77958177, gi|... - gi|77958177|ref|ZP_00822215.1| COG0704: Phosphate uptake regulator [Yersinia bercovieri ATCC 43970],...
3.0E-57 [1..240] [1..240]
gi|49613915, gi|... - gi|50123389|ref|YP_052556.1| transcriptional regulator PhoU [Pectobacterium atrosepticum SCRI1043], ...
7.0E-57 [1..235] [1..235]
PHOU_ECOLI - Phosphate transport system protein phoU - Escherichia coli
gi|218556291, gi... - gi|218556291|ref|YP_002389205.1| transcriptional regulator PhoU [Escherichia coli IAI1], gi|21836306...
gi|209914460, gi... - gi|209921201|ref|YP_002295285.1| transcriptional regulator PhoU [Escherichia coli SE11], gi|20991446...
gi|218697446, gi... - gi|218697446|ref|YP_002405113.1| transcriptional regulator PhoU [Escherichia coli 55989], gi|2183541...
gi|238861882, gi... - gi|238902815|ref|YP_002928611.1| negative regulator of PhoR/PhoB two-component regulator [Escherichi...
gi|251786989, gi... - gi|251786989|ref|YP_003001293.1| hypothetical protein B21_03552 [Escherichia coli BL21], gi|24237926...
gi|254290426, gi... - gi|254290426|ref|YP_003056174.1| negative regulator of PhoR/PhoB two-component regulator [Escherichi...
gi|253975577, gi... - gi|254163676|ref|YP_003046784.1| negative regulator of PhoR/PhoB two-component regulator [Escherichi...
gi|110807581, gi... - gi|110807581|ref|YP_691101.1| transcriptional regulator PhoU [Shigella flexneri 5 str. 8401], gi|110...
gi|74314262, gi|... - gi|74314262|ref|YP_312681.1| transcriptional regulator PhoU [Shigella sonnei Ss046], gi|73857739|gb|...
gi|81247429, gi|... - gi|82546018|ref|YP_409965.1| transcriptional regulator PhoU [Shigella boydii Sb227], gi|81247429|gb|...
gi|193063811, gi... - gi|75258263|ref|ZP_00729711.1| COG0704: Phosphate uptake regulator [Escherichia coli E22], gi|193063...
gi|188487360, gi... - gi|75514210|ref|ZP_00736518.1| COG0704: Phosphate uptake regulator [Escherichia coli 53638], gi|1884...
gi|85676314, gi|... - gi|89110283|ref|AP_004063.1| DNA-binding transcriptional regulator [Escherichia coli str. K-12 subst...
gi|56383953, gi|... - gi|56480402|ref|NP_709470.2| transcriptional regulator PhoU [Shigella flexneri 2a str. 301], gi|5638...
gi|75177713, gi|... - gi|75177713|ref|ZP_00697778.1| COG0704: Phosphate uptake regulator [Shigella boydii BS512], gi|18773...
gi|157076766, gi... - gi|75188479|ref|ZP_00701746.1| COG0704: Phosphate uptake regulator [Escherichia coli E24377A], gi|15...
gi|194435640, gi... - gi|83588411|ref|ZP_00927035.1| COG0704: Phosphate uptake regulator [Escherichia coli 101-1], gi|1944...
gi|75231006, gi|... - gi|75231006|ref|ZP_00717441.1| COG0704: Phosphate uptake regulator [Escherichia coli B7A], gi|191165...
gi|75236453, gi|... - gi|75236453|ref|ZP_00720549.1| COG0704: Phosphate uptake regulator [Escherichia coli E110019], gi|19...
gi|75197620, gi|... - gi|75197620|ref|ZP_00707690.1| COG0704: Phosphate uptake regulator [Escherichia coli HS], gi|1571632...
EG10735 - negative regulator of PhoR /PhoB two-component regulator / Negative regulator of pho regulon; may hav...
gi|194413840, gi... - gi|75210666|ref|ZP_00710807.1| COG0704: Phosphate uptake regulator [Escherichia coli B171], gi|19442...
gi|124499467, gi... - gi|124530062|ref|ZP_01700845.1| phosphate uptake regulator, PhoU [Escherichia coli B], gi|124499467|...
gi|169891061, gi... - gi|170083226|ref|YP_001732546.1| negative regulator of PhoR/PhoB two-component regulator [Escherichi...
gi|170022239, gi... - gi|170022239|ref|YP_001727193.1| transcriptional regulator PhoU [Escherichia coli ATCC 8739], gi|169...
PHOU_SHIFL - Phosphate-specific transport system accessory protein PhoU OS=Shigella flexneri GN=phoU PE=3 SV=1
gi|30065039, gi|... - gi|30065039|ref|NP_839210.1| transcriptional regulator PhoU [Shigella flexneri 2a str. 2457T], gi|30...
EG10735 - negative regulator of PhoR /PhoB two-component regulator / Negative regulator of pho regulon; may hav...
1.0E-56 [1..238] [1..238]

Back

Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSLNLNKHI SGQFNAELES IRTQVMTMGG MVEQQLSDAI TAMHNQDSEL AKRVVEGDHQ  60
   61 VNMMEVAIDE ACVRIIAKRQ PTASDLRLVM AIIKTIAELE RIGDVADKIC RTALEKFSQQ 120
  121 HQPLLVSLES LGRHTVQMLH DVLDAFARMD LDEAVRIYRE DKKVDQEYEG IVRQLMTYMM 180
  181 EDSRTIPSVL TALFCARSIE RIGDRCQNIC EYIFYFVKGQ DFRHVGGDEL DKLLAGKDPK 240
  241 E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 1t72A
Description: Crystal structure of phosphate transport system protein phoU from Aquifex aeolicus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.52706367695557 bayes_pls_golite062009
nucleic acid binding 1.40207651011289 bayes_pls_golite062009
DNA binding 1.39485368870356 bayes_pls_golite062009
transcription factor activity 1.27583598395229 bayes_pls_golite062009
binding 0.775039544296942 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle