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View Structure Prediction Details

Protein: gi|195335482, gi...
Organism: Drosophila sechellia
Length: 634 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|195335482, gi....

Description E-value Query
Range
Subject
Range
gi|76689279 - gi|76689279|ref|XP_881322.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
537.0 [0..1] [633..10]

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Predicted Domain #1
Region A:
Residues: [1-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLYVGDLP QDVNESGLFD KFSSAGPVLS IRVCRDVITR RSLGYAYVNF QQPADAERAL  60
   61 DTMNFDLVRN KPIRIMWSQR DPSLRRSGVG NVFIKNLDRA IDNKAIYDTF SAFGNILSCK 120
  121 VATDEKGNSK GYGFVHFETE EAANTSIDKV NGMLLNGKKV YVGKFIPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.39794
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
4.45006565905155 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
poly-pyrimidine tract binding 2.79052809544187 bayes_pls_golite062009
structural molecule activity 2.78501986457503 bayes_pls_golite062009
poly(U) RNA binding 2.49013736906028 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
protein binding 2.17260848225967 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
hydrolase activity 1.59923957614061 bayes_pls_golite062009
snRNA binding 1.44241647066188 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
transcription repressor activity 1.06887262556449 bayes_pls_golite062009
transcription activator activity 1.02778561397221 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.632534695085793 bayes_pls_golite062009
eukaryotic initiation factor 4G binding 0.597542453741953 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
U1 snRNA binding 0.290135317640781 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [169-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEREKELGEK AKLFTNVYVK NFTEDFDDEK LKEFFEPYGK ITSYKVMSKE DGKSKGFGFV  60
   61 AFETTEAAEA AVQALNGKDM GEGKSLYVAR AQKKAERQQE LKRKFEELKQ KRHE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 2d9pA
Description: No description for 2d9pA was found.

Predicted Domain #3
Region A:
Residues: [283-406]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVFGVNLYVK NLDDTIDDDR LRIAFSPYGN ITSAKVMTDE EGRSKGFGFV CFNAASEATC  60
   61 AVTELNGRVV GSKPLYVALA QRKEERKAHL ASQYMRHMTG MRMQQLGQIY QPNAASGFFV 120
  121 PTLP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.49
Match: 1h2tZ
Description: CBP20, 20KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.32219487559982 bayes_pls_golite062009
mRNA binding 4.87640532914983 bayes_pls_golite062009
nucleic acid binding 4.65259034341669 bayes_pls_golite062009
4.22120207254226 bayes_pls_golite062009
binding 3.48033873254013 bayes_pls_golite062009
structural molecule activity 2.79390010162962 bayes_pls_golite062009
single-stranded RNA binding 2.55628738360472 bayes_pls_golite062009
poly-pyrimidine tract binding 2.38400992482878 bayes_pls_golite062009
transcription regulator activity 2.2045206027152 bayes_pls_golite062009
poly(U) RNA binding 2.13305841145089 bayes_pls_golite062009
protein binding 2.10850948869511 bayes_pls_golite062009
DNA binding 1.99030664201171 bayes_pls_golite062009
hydrolase activity 1.62800695894716 bayes_pls_golite062009
snRNA binding 1.15643072278378 bayes_pls_golite062009
transcription factor activity 1.09958329302628 bayes_pls_golite062009
transcription repressor activity 1.07516027015942 bayes_pls_golite062009
transcription activator activity 1.03081648377979 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.633093884585572 bayes_pls_golite062009
eukaryotic initiation factor 4G binding 0.468183942177665 bayes_pls_golite062009
mRNA 3'-UTR binding 0.462558743683805 bayes_pls_golite062009
sequence-specific DNA binding 0.327072171076297 bayes_pls_golite062009
translation regulator activity 0.246220338604608 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.0127733116412899 bayes_pls_golite062009
U1 snRNA binding 0.00409932271658597 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [407-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNQRFFGSQV ATQMRNTPRW VPQVRPPAAI QGVQAGAAAA GGFQGTAGAV PTQFRSAAAG  60
   61 ARGAQPQVQG THAAAAAANN MRNTGARAIT GQQTAAPNMQ IPGAQIAGGA QQRTSNYKYT 120
  121 SNMRNPPVPQ LHQTQPIPQQ LQGKNSEKLI ASLLANA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [564-634]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPQEQKQILG ERLYPMIEHM HANLAGKITG MLLEIENSEL LHMIEDQEAL KAKVEEAVAV  60
   61 LQVHRVTEPA N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle