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View Structure Prediction Details

Protein: gi|220957662, gi...
Organism: synthetic construct
Length: 257 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220957662, gi....

Description E-value Query
Range		 Subject
Range
gi|5081630 - gi|5081630|gb|AAD39474.1|AF139064_1 origin recognition complex subunit 6 [Drosophila melanogaster]
 347.0 [0..1] [257..1]
HGNC:17151|MIM:6... - recognition complex, subunit 6 like (yeast)
gi|117646404, gi... - gi|117646818|emb|CAL37524.1| hypothetical protein [synthetic construct], gi|117646404|emb|CAL38669.1...
ORC6L - origin recognition complex, subunit 6 like (yeast)
 304.0 [0..2] [241..3]
gi|114662327 - gi|114662327|ref|XP_001161833.1| PREDICTED: origin recognition complex subunit 6 isoform 4 [Pan trog...
 304.0 [0..2] [241..3]
gi|109128387 - gi|109128387|ref|XP_001113625.1| PREDICTED: similar to origin recognition complex subunit 6 [Macaca ...
 300.0 [0..2] [241..3]
ORC6_ARATH - Origin of replication complex subunit 6 OS=Arabidopsis thaliana GN=ORC6 PE=1 SV=2
 296.0 [0..5] [233..3]
gi|27658770, gi|... - gi|76096324|ref|NP_001028862.1| origin recognition complex, subunit 6 like [Rattus norvegicus], gi|7...
 293.0 [0..2] [240..3]
ORC6_BOVIN - Origin recognition complex subunit 6 OS=Bos taurus GN=ORC6 PE=2 SV=1
 291.0 [0..4] [241..5]
ORC6_MOUSE - Origin recognition complex subunit 6 OS=Mus musculus GN=Orc6 PE=1 SV=1
 289.0 [0..2] [240..3]
ORC6_ORYSJ - Origin of replication complex subunit 6 OS=Oryza sativa subsp. japonica GN=ORC6 PE=3 SV=1
 287.0 [0..5] [239..3]

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Predicted Domain #1
Region A:
Residues: [1-257] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTLIEQLIT KMGLREEPNV LEKTTELVRL LELRSTNVPL QINEYGKIVL CADLASCMIG  60
   61 IAFDKEQALK LSGLRKSQYL NNKRMFEKLL DLNKLASVND ICVQLGLNEV ARKAEELMTL 120
  121 FKGVAATEDM GTDTSHPQYA TMAVFQACRL LKKKVSKSKL MPFSNLRPSQ FQLLEQQWER 180
  181 MIAKHHKESK VPSSTDMEGK LKENQNENIK GHEAKKAHKP PPEDYEIWKA RMLAKAQAKL 240
  241 KELEASQSHM DSQLLEA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.96
Match: 1kxuA
Description: CYCLIN H, A POSITIVE REGULATORY SUBUNIT OF CDK ACTIVATING KINASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.75688185850223 bayes_pls_golite062009
binding 2.37916921859542 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.37399236069363 bayes_pls_golite062009
nucleic acid binding 2.06743451505655 bayes_pls_golite062009
DNA binding 1.95321993038755 bayes_pls_golite062009
transcription repressor activity 1.41828738664896 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 1.41497909264171 bayes_pls_golite062009
protein binding 1.37207701115974 bayes_pls_golite062009
transcription factor activity 1.22628491144894 bayes_pls_golite062009
protein kinase regulator activity 1.21941169140389 bayes_pls_golite062009
kinase regulator activity 1.18590233040331 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.962670695182671 bayes_pls_golite062009
transcription factor binding 0.655253705928308 bayes_pls_golite062009
enzyme regulator activity 0.461517963237846 bayes_pls_golite062009
transcription coactivator activity 0.0843751392410543 bayes_pls_golite062009
transcription activator activity 0.0606514459376675 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
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