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View Structure Prediction Details

Protein: gi|220943764
Organism: synthetic construct
Length: 778 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220943764.

Description E-value Query
Range
Subject
Range
gi|73985557 - gi|73985557|ref|XP_533833.2| PREDICTED: similar to glutaminyl-tRNA synthetase isoform 1 [Canis famil...
867.0 [0..1] [777..1]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGDDLIAKF QALGMSEQKA KETLKNANVT KNLQLSLAAA GSATLSDGTG MLIYHMATKL  60
   61 KPQTADHLPL LVRYIVEHKL DNTQRVDAAL EYLLKCGQSL NANIDLQALE KECGVGVVVT 120
  121 PEQIERTVQA KIKASYKEAL LEQRYHF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 92.657577
Match: PF04558.6
Description: No description for PF04558.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [148-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSFKILQDVR GELKWADAKS VKAAIDVEIF DLLGPKTEAD LKPQTKANDK PKAAKPKAEV  60
   61 TPAAQTAEAA SDGATTISEL MKTKVHFHAP GENFKADGYV VT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1iq0A
Description: Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [250-778]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EHTERLLKEH LARTGGKVHT RFPPEPNGIL HIGHAKAINI NFGYAAAHDG VCYLRYDDTN  60
   61 PEKEEEKFFL AIKEMVEWLG YKPFKITYSS DNFQQLYEWA VVLINKGLAY VCHQKAEELK 120
  121 GFNPKPSPWR ERPIEESLRL FEDMKRGKID EGAATLRMKV TLEEGKMDPV AYRIKFISHH 180
  181 RTGSDWCIYP TYDYTHCLCD SLEDITHSLC TKEFQSRRSS YYWLCNALGI YCPVQWEYGR 240
  241 LNMNYALVSK RKIAKLITEQ IVHDWDDPRL FTLTALRRRG FPAEAINNFC AQMGVTGAQI 300
  301 AVDPAMLEAA VRDVLNVTAP RRLVVLEPLK VTIKNFPHAA PVQLEVPDFP QNPQQGTHKI 360
  361 TLDKVIYIEQ GDFKLEPEKG YRRLAPKQSV GLRHAGLVIS VDEIVKDPAT GQVVELICTS 420
  421 QPAEQAEKPK AFVQWVSQPI QLEVRLYEQL FKHKNPEDPN EVPGGFLSDI SEQSMSVVVA 480
  481 FADRALNQAK VYDKFQFERI GFFSVDPDTS ANHLVFNRTV GLKEDAGKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 171.0
Match: 1o0bA
Description: Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain; Glutaminyl-tRNA synthetase (GlnRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glutamine-tRNA ligase activity 7.66556935228325 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 7.16276509815667 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.16276509815667 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.13957775963187 bayes_pls_golite062009
ligase activity 6.11211476973434 bayes_pls_golite062009
lysine-tRNA ligase activity 4.64665624411373 bayes_pls_golite062009
structural constituent of ribosome 4.61484562096458 bayes_pls_golite062009
structural molecule activity 4.261982318682 bayes_pls_golite062009
glutamate-tRNA ligase activity 2.63681738794687 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
5S rRNA binding 2.25646775578129 bayes_pls_golite062009
rRNA binding 2.12571610259264 bayes_pls_golite062009
methionine-tRNA ligase activity 2.01261843164558 bayes_pls_golite062009
tyrosine-tRNA ligase activity 1.88984817882585 bayes_pls_golite062009
tryptophan-tRNA ligase activity 1.14187887833901 bayes_pls_golite062009
arginine-tRNA ligase activity 1.13743634264647 bayes_pls_golite062009
nucleotidyltransferase activity 1.06535308346284 bayes_pls_golite062009
cysteine-tRNA ligase activity 0.844943947059557 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.625793556381714 bayes_pls_golite062009
binding 0.47302762432927 bayes_pls_golite062009
nucleic acid binding 0.161799496958314 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle