YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213162272
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E00-7866
Length:	324 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213162272.

Description	E-value	Query Range	Subject Range
gi\|237705300, gi... - gi\|237705300\|ref\|ZP_04535781.1\| transcriptional regulator CysB [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|238860946, gi... - gi\|238900508\|ref\|YP_002926304.1\| DNA-binding transcriptional dual regulator, O-acetyl-L-serine-bindi... gi\|242377053, gi... - gi\|251784780\|ref\|YP_002999084.1\| hypothetical protein B21_01261 [Escherichia coli BL21], gi\|24237705... gi\|253324772, gi... - gi\|254288163\|ref\|YP_003053911.1\| DNA-binding transcriptional dual regulator, O-acetyl-L-serine-bindi... gi\|253973256, gi... - gi\|254161355\|ref\|YP_003044463.1\| DNA-binding transcriptional dual regulator, O-acetyl-L-serine-bindi... gi\|254792863, gi... - gi\|254792863\|ref\|YP_003077700.1\| DNA-binding transcriptional dual regulator, O-acetyl-L-serine-bindi... gi\|187731082, gi... - gi\|187731082\|ref\|YP_001880106.1\| HTH-type transcriptional regulator CysB [Shigella boydii CDC 3083-9... gi\|117623535, gi... - gi\|117623535\|ref\|YP_852448.1\| transcriptional regulator CysB [Escherichia coli APEC O1], gi\|11551265... gi\|169888787, gi... - gi\|170080952\|ref\|YP_001730272.1\| DNA-binding transcriptional dual regulator, O-acetyl-L-serine-bindi... gi\|124500578, gi... - gi\|124528346\|ref\|ZP_01699656.1\| transcriptional regulator, LysR family [Escherichia coli B], gi\|1245... gi\|190903333, gi... - gi\|191166684\|ref\|ZP_03028512.1\| HTH-type transcriptional regulator CysB [Escherichia coli B7A], gi\|1... gi\|188496048, gi... - gi\|188496048\|ref\|ZP_03003318.1\| HTH-type transcriptional regulator CysB [Escherichia coli 53638], gi... CYSB_ECOLI - HTH-type transcriptional regulator cysB (Cys regulon transcriptional activator) - Escherichia coli gi\|192956708, gi... - gi\|193069955\|ref\|ZP_03050903.1\| HTH-type transcriptional regulator CysB [Escherichia coli E110019], ... gi\|193062611, gi... - gi\|193062611\|ref\|ZP_03043705.1\| HTH-type transcriptional regulator CysB [Escherichia coli E22], gi\|1... gi\|194416419, gi... - gi\|194435339\|ref\|ZP_03067546.1\| HTH-type transcriptional regulator CysB [Shigella dysenteriae 1012],... gi\|194415824, gi... - gi\|194425769\|ref\|ZP_03058325.1\| HTH-type transcriptional regulator CysB [Escherichia coli B171], gi\|... gi\|110641508, gi... - gi\|110641508\|ref\|YP_669238.1\| transcriptional regulator CysB [Escherichia coli 536], gi\|110343100\|gb... gi\|168763575, gi... - gi\|189366226\|gb\|EDU84642.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 str. E... gi\|168751167, gi... - gi\|188014764\|gb\|EDU52886.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 str. E... gi\|187769279, gi... - gi\|187769279\|gb\|EDU33123.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 str. E... gi\|89108121, gi\|... - gi\|89108121\|ref\|AP_001901.1\| DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding [... gi\|189359957, gi... - gi\|189359957\|gb\|EDU78376.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 str. E... gi\|91072141, gi\|... - gi\|91210567\|ref\|YP_540553.1\| transcriptional regulator CysB [Escherichia coli UTI89], gi\|91072141\|gb... gi\|169755289, gi... - gi\|170020361\|ref\|YP_001725315.1\| transcriptional regulator CysB [Escherichia coli ATCC 8739], gi\|169... gi\|13361312, gi\|... - gi\|15831101\|ref\|NP_309874.1\| transcriptional regulator CysB [Escherichia coli O157:H7 str. Sakai], g... gi\|168783780, gi... - gi\|188998962\|gb\|EDU67948.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 str. E... gi\|81245680, gi\|... - gi\|82544269\|ref\|YP_408216.1\| transcriptional regulator CysB [Shigella boydii Sb227], gi\|81245680\|gb\|... gi\|191170907, gi... - gi\|75242074\|ref\|ZP_00725868.1\| COG0583: Transcriptional regulator [Escherichia coli F11], gi\|1911709... EG10184 - N-acetylserine-responsive cysteine regulon transcriptional activator; autorepressor / Transcriptiona... CYSB_ECOL6 - HTH-type transcriptional regulator CysB OS=Escherichia coli O6 GN=cysB PE=3 SV=1 CYSB_ECOL6 - HTH-type transcriptional regulator CysB OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPE... CYSB_ECO57 - HTH-type transcriptional regulator CysB OS=Escherichia coli O157:H7 GN=cysB PE=3 SV=1 EG10184 - N-acetylserine-responsive cysteine regulon transcriptional activator; autorepressor / Transcriptiona... gi\|15801904, gi\|... - gi\|15801904\|ref\|NP_287924.1\| transcriptional regulator CysB [Escherichia coli O157:H7 EDL933], gi\|12... gi\|157066460, gi... - gi\|157160780\|ref\|YP_001458098.1\| transcriptional regulator CysB [Escherichia coli HS], gi\|157066460\|... gi\|218360596, gi... - gi\|218553828\|ref\|YP_002386741.1\| transcriptional regulator CysB [Escherichia coli IAI1], gi\|21836059... gi\|217317662, gi... - gi\|217329223\|ref\|ZP_03445303.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 st... gi\|218689266, gi... - gi\|218689266\|ref\|YP_002397478.1\| transcriptional regulator CysB [Escherichia coli ED1a], gi\|21842683... gi\|218558263, gi... - gi\|218558263\|ref\|YP_002391176.1\| transcriptional regulator CysB [Escherichia coli S88], gi\|218365032... gi\|218431896, gi... - gi\|218704799\|ref\|YP_002412318.1\| transcriptional regulator CysB [Escherichia coli UMN026], gi\|218431... gi\|218351579, gi... - gi\|218694847\|ref\|YP_002402514.1\| transcriptional regulator CysB [Escherichia coli 55989], gi\|2183515... gi\|157157588, gi... - gi\|157157588\|ref\|YP_001462572.1\| transcriptional regulator CysB [Escherichia coli E24377A], gi\|15707... gi\|195939211 - gi\|195939211\|ref\|ZP_03084593.1\| transcriptional regulator CysB [Escherichia coli O157:H7 str. EC4024... gi\|194424053, gi... - gi\|194437070\|ref\|ZP_03069169.1\| HTH-type transcriptional regulator CysB [Escherichia coli 101-1], gi... gi\|208816350, gi... - gi\|208816350\|ref\|ZP_03257529.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 st... gi\|208724585, gi... - gi\|208811079\|ref\|ZP_03252912.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 st... gi\|209399190, gi... - gi\|209399190\|ref\|YP_002270329.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 s... gi\|208819393, gi... - gi\|208819393\|ref\|ZP_03259713.1\| HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 st... gi\|215486570, gi... - gi\|215486570\|ref\|YP_002329001.1\| transcriptional regulator CysB [Escherichia coli O127:H6 str. E2348... gi\|209918514, gi... - gi\|209918514\|ref\|YP_002292598.1\| transcriptional regulator CysB [Escherichia coli SE11], gi\|20991177...	4.0E-72	[1..324]	[1..324]
gi\|24112672, gi\|... - gi\|24112672\|ref\|NP_707182.1\| transcriptional regulator CysB [Shigella flexneri 2a str. 301], gi\|2405... gi\|30041045, gi\|... - gi\|30062797\|ref\|NP_836968.1\| transcriptional regulator CysB [Shigella flexneri 2a str. 2457T], gi\|30... gi\|110805276, gi... - gi\|110805276\|ref\|YP_688796.1\| transcriptional regulator CysB [Shigella flexneri 5 str. 8401], gi\|110...	6.0E-72	[1..324]	[1..324]
gi\|81240782, gi\|... - gi\|82776634\|ref\|YP_402983.1\| transcriptional regulator CysB [Shigella dysenteriae Sd197], gi\|8124078...	1.0E-71	[1..324]	[1..324]
gi\|74312356, gi\|... - gi\|74312356\|ref\|YP_310775.1\| transcriptional regulator CysB [Shigella sonnei Ss046], gi\|73855833\|gb\|...	2.0E-71	[1..324]	[1..324]
gi\|194458733, gi... - gi\|194472369\|ref\|ZP_03078353.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp. ... gi\|197249782, gi... - gi\|197249782\|ref\|YP_002146314.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp.... gi\|197262598, gi... - gi\|197262598\|ref\|ZP_03162672.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp. ... gi\|205272394, gi... - gi\|205352613\|ref\|YP_002226414.1\| transcriptional regulator CysB [Salmonella enterica subsp. enterica... gi\|205350846, gi... - gi\|205350846\|gb\|EDZ37477.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp. ente... gi\|195634558, gi... - gi\|195634558\|gb\|EDX52910.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp. ente... gi\|168819533, gi... - gi\|205343792\|gb\|EDZ30556.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp. ente... gi\|194449730, gi... - gi\|194449730\|ref\|YP_002045759.1\| transcriptional regulator CysB [Salmonella enterica subsp. enterica... CYSB_SALTY - HTH-type transcriptional regulator cysB OS=Salmonella typhimurium GN=cysB PE=1 SV=1 gi\|205325067, gi... - gi\|205325067\|gb\|EDZ12906.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp. ente... gi\|167993765, gi... - gi\|205328284\|gb\|EDZ15048.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp. ente... gi\|168230149, gi... - gi\|205335560\|gb\|EDZ22324.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp. ente... gi\|205339414, gi... - gi\|205339414\|gb\|EDZ26178.1\| HTH-type transcriptional regulator CysB [Salmonella enterica subsp. ente... CYSB_SALTY - HTH-type transcriptional regulator CysB OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 7007... CYSB_SALTY - HTH-type transcriptional regulator CysB OS=Salmonella typhimurium GN=cysB PE=1 SV=1 lcl\|NC_016856.1_... - [gene=cysB] [protein=transcriptional regulator CysB] [protein_id=YP_005237636.1] [location=complemen... gi\|207856774, gi... - gi\|207856774\|ref\|YP_002243425.1\| transcriptional regulator CysB [Salmonella enterica subsp. enterica... gi\|238911895 - gi\|238911895\|ref\|ZP_04655732.1\| transcriptional regulator CysB [Salmonella enterica subsp. enterica ...	1.0E-70	[1..324]	[1..324]
gi\|238894332, gi... - gi\|238894332\|ref\|YP_002919066.1\| transcriptional regulator for cysteine regulon [Klebsiella pneumoni... gi\|628813 - gi\|628813\|pir\|\|S43835 regulatory protein cysB - Klebsiella sp. (ATCC 15380) CYSB_KLEAE - (P45600) HTH-type transcriptional regulator cysB (Cys regulon transcriptional activator) CYSB_KLEPN - HTH-type transcriptional regulator CysB OS=Klebsiella pneumoniae GN=cysB PE=1 SV=2 gi\|152969825, gi... - gi\|152969825\|ref\|YP_001334934.1\| transcriptional regulator CysB [Klebsiella pneumoniae subsp. pneumo...	1.0E-70	[1..324]	[1..324]
gi\|36785760, gi\|... - gi\|37526329\|ref\|NP_929673.1\| transcriptional regulator CysB [Photorhabdus luminescens subsp. laumond...	2.0E-70	[1..323]	[1..323]
gi\|194538955, gi... - gi\|75854442\|ref\|ZP_00762135.1\| COG0583: Transcriptional regulator [Vibrio sp. Ex25], gi\|254229941\|re...	2.0E-70	[1..324]	[1..324]
gi\|91191158, gi\|... - gi\|91224247\|ref\|ZP_01259510.1\| putative transcription regulator protein [Vibrio alginolyticus 12G01]...	2.0E-70	[6..300]	[7..297]
gi\|511012 - gi\|511012\|emb\|CAA55380.1\| CYSB protein [Klebsiella aerogenes]	2.0E-70	[1..324]	[1..324]

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Predicted Domain #1

Region A:
Residues: [1-324]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLQQLRYIV EVVNHNLNVS STAEGLYTSQ PGISKQVRML EDELGIQIFA RSGKHLTQVT  60
   61 PAGQEIIRIA REVLSKVDAI KSVAGEHTWP DKGSLYIATT HTQARYALPG VIKGFIERYP 120
  121 RVSLHMHQGS PTQIAEAVSK GNADFAIATE ALHLYDDLVM LPCYHWNRSI VVTPDHPLAA 180
  181 TSSITIEALA QYPLVTYTFG FTGRSELDTA FNRAGLTPRI VFTATDADVI KTYVRLGLGV 240
  241 GVIASMAVDP LTDPDLVRID AHDIFSHSTT KIGFRRSTFL RSYMYDFIQR FAPHLTRDVV 300
  301 DTAVALRSNE EIEAMFQDIK LPEK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.09691
Match:	1al3A
Description:	COFACTOR BINDING FRAGMENT OF CYSB FROM KLEBSIELLA AEROGENES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.06846313752146	bayes_pls_golite062009
transcription factor activity	1.54776226622667	bayes_pls_golite062009
DNA binding	1.53867658911479	bayes_pls_golite062009
nucleic acid binding	1.45471488657915	bayes_pls_golite062009
binding	1.29220115989941	bayes_pls_golite062009
catalytic activity	1.04475291968158	bayes_pls_golite062009
protein binding	0.0639574144110515	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: