YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213425949
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E02-1180
Length:	450 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213425949.

Description	E-value	Query Range	Subject Range
gi\|224582071, gi... - gi\|224582071\|ref\|YP_002635869.1\| hypothetical protein SPC_0239 [Salmonella enterica subsp. enterica ... gi\|62178793, gi\|... - gi\|62178793\|ref\|YP_215210.1\| zinc metallopeptidase [Salmonella enterica subsp. enterica serovar Chol...	2.0E-92	[1..450]	[1..450]
RSEP_SALT1 - Regulator of sigma-E protease RseP OS=Salmonella typhimurium (strain 14028s / SGSC 2262) GN=rsep PE=... gi\|204926960, gi... - gi\|204926960\|ref\|ZP_03218162.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serova... RSEP_SALTY - Regulator of sigma E protease OS=Salmonella typhimurium GN=rseP PE=3 SV=1 gi\|200388259, gi... - gi\|200388259\|ref\|ZP_03214871.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serova... gi\|205271341, gi... - gi\|205351560\|ref\|YP_002225361.1\| zinc metallopeptidase RseP [Salmonella enterica subsp. enterica ser... gi\|197249547, gi... - gi\|197249547\|ref\|YP_002145228.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serov... gi\|56126753, gi\|... - gi\|56412496\|ref\|YP_149571.1\| zinc metallopeptidase RseP [Salmonella enterica subsp. enterica serovar... gi\|194735257, gi... - gi\|194735257\|ref\|YP_002113246.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serov... gi\|197361431, gi... - gi\|197361431\|ref\|YP_002141067.1\| zinc metallopeptidase RseP [Salmonella enterica subsp. enterica ser... ECFE_SALTY, RSEP... - Regulator of sigma E protease OS=Salmonella typhimurium GN=rseP PE=3 SV=1, Protease ecfE - Salmonell... gi\|197243939, gi... - gi\|197265684\|ref\|ZP_03165758.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serova... gi\|194444218, gi... - gi\|194444218\|ref\|YP_002039463.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serov... gi\|168823252, gi... - gi\|205340483\|gb\|EDZ27247.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serovar We... gi\|194469383, gi... - gi\|194469383\|ref\|ZP_03075367.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serova... gi\|194407707, gi... - gi\|194449403\|ref\|YP_002044213.1\| zinc metallopeptidase RseP [Salmonella enterica subsp. enterica ser... gi\|168244990, gi... - gi\|205336216\|gb\|EDZ22980.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serovar He... gi\|197291779, gi... - gi\|197291779\|gb\|EDY31129.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serovar Sc... RSEP_SALTY - Regulator of sigma E protease OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=rse... gi\|168464213, gi... - gi\|195632931\|gb\|EDX51385.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serovar Ne... gi\|205347437, gi... - gi\|205347437\|gb\|EDZ34068.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serovar Ha... gi\|205322186, gi... - gi\|205322186\|gb\|EDZ10025.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serovar Sa... gi\|161361959, gi... - gi\|161612595\|ref\|YP_001586560.1\| zinc metallopeptidase [Salmonella enterica subsp. enterica serovar ... gi\|168230531, gi... - gi\|205335120\|gb\|EDZ21884.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serovar Ke... gi\|167990109, gi... - gi\|205331445\|gb\|EDZ18209.1\| RIP metalloprotease RseP [Salmonella enterica subsp. enterica serovar 4,...	2.0E-92	[1..450]	[1..450]
gi\|74310796, gi\|... - gi\|74310796\|ref\|YP_309215.1\| zinc metallopeptidase [Shigella sonnei Ss046], gi\|73854273\|gb\|AAZ86980....	4.0E-91	[1..450]	[1..450]
EG12436 - inner membrane zinc RIP metalloprotease; RpoE activator, by degrading RseA; cleaved signal peptide e... RSEP_ECO57 - Regulator of sigma E protease OS=Escherichia coli O157:H7 GN=rseP PE=3 SV=1 gi\|15799858, gi\|... - gi\|15799858\|ref\|NP_285870.1\| zinc metallopeptidase [Escherichia coli O157:H7 EDL933], gi\|12512901\|gb... gi\|4902917, gi\|8... - gi\|89107056\|ref\|AP_000836.1\| zinc metallopeptidase [Escherichia coli str. K-12 substr. W3110], gi\|49... gi\|254791309, gi... - gi\|254791309\|ref\|YP_003076146.1\| inner membrane zinc RIP metalloprotease [Escherichia coli O157:H7 s... gi\|253972196, gi... - gi\|254160295\|ref\|YP_003043403.1\| zinc metallopeptidase [Escherichia coli B str. REL606], gi\|25397219... gi\|253325841, gi... - gi\|254287098\|ref\|YP_003052846.1\| zinc metallopeptidase [Escherichia coli BL21(DE3)], gi\|253976405\|gb... gi\|187767687, gi... - gi\|187767687\|gb\|EDU31531.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4196], gi\|1687... gi\|251783734, gi... - gi\|251783734\|ref\|YP_002998038.1\| hypothetical protein B21_00173 [Escherichia coli BL21], gi\|24237600... gi\|189000422, gi... - gi\|189000422\|gb\|EDU69408.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4076], gi\|1687... gi\|238863792, gi... - gi\|238899574\|ref\|YP_002925370.1\| zinc metallopeptidase [Escherichia coli BW2952], gi\|238863792\|gb\|AC... gi\|189371079, gi... - gi\|189371079\|gb\|EDU89495.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC869], gi\|16878... gi\|170079812, gi... - gi\|170079812\|ref\|YP_001729132.1\| inner membrane zinc RIP metalloprotease [Escherichia coli str. K-12... gi\|194439126, gi... - gi\|83585492\|ref\|ZP_00924137.1\| COG0750: Predicted membrane-associated Zn-dependent proteases 1 [Esch... gi\|13359634, gi\|... - gi\|15829432\|ref\|NP_308205.1\| zinc metallopeptidase RseP [Escherichia coli O157:H7 str. Sakai], gi\|13... gi\|195938142 - gi\|195938142\|ref\|ZP_03083524.1\| zinc metallopeptidase [Escherichia coli O157:H7 str. EC4024] gi\|75210499, gi\|... - gi\|75210499\|ref\|ZP_00710650.1\| COG0750: Predicted membrane-associated Zn-dependent proteases 1 [Esch... gi\|110804228, gi... - gi\|110804228\|ref\|YP_687748.1\| zinc metallopeptidase [Shigella flexneri 5 str. 8401], gi\|110613776\|gb... gi\|208808080, gi... - gi\|208808080\|ref\|ZP_03250417.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4206], gi\|... gi\|75258833, gi\|... - gi\|75258833\|ref\|ZP_00730223.1\| COG0750: Predicted membrane-associated Zn-dependent proteases 1 [Esch... gi\|208733543, gi... - gi\|208812266\|ref\|ZP_03253595.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4045], gi\|... gi\|208738909, gi... - gi\|208818786\|ref\|ZP_03259106.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4042], gi\|... ECFE_ECOLI - Protease ecfE (EC 3.4.24.-) - Escherichia coli gi\|188014570, gi... - gi\|188014570\|gb\|EDU52692.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4113], gi\|1687... gi\|168755789, gi... - gi\|189357018\|gb\|EDU75437.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4401], gi\|1687... gi\|189364911, gi... - gi\|189364911\|gb\|EDU83327.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4501], gi\|1687... gi\|168770350, gi... - gi\|189360726\|gb\|EDU79145.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4486], gi\|1687... EG12436 - inner membrane zinc RIP metalloprotease; RpoE activator, by degrading RseA; cleaved signal peptide e... gi\|209160522, gi... - gi\|209399122\|ref\|YP_002268784.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4115], gi... gi\|209910625, gi... - gi\|209917366\|ref\|YP_002291450.1\| zinc metallopeptidase RseP [Escherichia coli SE11], gi\|209910625\|db... gi\|217325674, gi... - gi\|217325674\|ref\|ZP_03441758.1\| RIP metalloprotease RseP [Escherichia coli O157:H7 str. TW14588], gi...	5.0E-91	[1..450]	[1..450]
gi\|218363886, gi... - gi\|218557117\|ref\|YP_002390030.1\| zinc metallopeptidase RseP [Escherichia coli S88], gi\|218363886\|emb... gi\|191172791, gi... - gi\|75240235\|ref\|ZP_00724182.1\| COG0750: Predicted membrane-associated Zn-dependent proteases 1 [Esch... gi\|218425615, gi... - gi\|218688051\|ref\|YP_002396263.1\| zinc metallopeptidase RseP [Escherichia coli ED1a], gi\|218425615\|em... gi\|227838049, gi... - gi\|227884911\|ref\|ZP_04002716.1\| RIP metalloprotease RseP [Escherichia coli 83972], gi\|227838049\|gb\|E... gi\|110640395, gi... - gi\|110640395\|ref\|YP_668123.1\| zinc metallopeptidase RseP [Escherichia coli 536], gi\|110341987\|gb\|ABG... gi\|117622461, gi... - gi\|117622461\|ref\|YP_851374.1\| zinc metallopeptidase [Escherichia coli APEC O1], gi\|115511585\|gb\|ABI9...	5.0E-91	[1..450]	[1..450]
gi\|218552757, gi... - gi\|218552757\|ref\|YP_002385670.1\| zinc metallopeptidase RseP [Escherichia coli IAI1], gi\|218359525\|em... gi\|75194386, gi\|... - gi\|75194386\|ref\|ZP_00704456.1\| COG0750: Predicted membrane-associated Zn-dependent proteases 1 [Esch...	5.0E-91	[1..450]	[1..450]
gi\|30039975, gi\|... - gi\|30061733\|ref\|NP_835904.1\| zinc metallopeptidase [Shigella flexneri 2a str. 2457T], gi\|30039975\|gb... gi\|56479619, gi\|... - gi\|56479619\|ref\|NP_706121.2\| zinc metallopeptidase [Shigella flexneri 2a str. 301], gi\|56383170\|gb\|A...	5.0E-91	[1..450]	[1..450]
gi\|26246122, gi\|... - gi\|26246122\|ref\|NP_752161.1\| zinc metallopeptidase [Escherichia coli CFT073], gi\|26106519\|gb\|AAN7870... gi\|226902247, gi... - gi\|237704335\|ref\|ZP_04534816.1\| zinc metallopeptidase [Escherichia sp. 3_2_53FAA], gi\|226902247\|gb\|E... gi\|91209246, gi\|... - gi\|91209246\|ref\|YP_539232.1\| zinc metallopeptidase [Escherichia coli UTI89], gi\|91070820\|gb\|ABE05701...	8.0E-91	[1..450]	[16..465]
gi\|157156244, gi... - gi\|75189271\|ref\|ZP_00702538.1\| COG0750: Predicted membrane-associated Zn-dependent proteases 1 [Esch...	9.0E-91	[1..450]	[1..450]
gi\|28851986, gi\|... - gi\|28868747\|ref\|NP_791366.1\| membrane-associated zinc metalloprotease, putative [Pseudomonas syringa... tr\|Q886N6\|Q886N6... - Membrane-associated zinc metalloprotease, putative OS=Pseudomonas syringae pv. tomato (strain DC3000...	3.0E-90	[2..450]	[1..450]

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Predicted Domain #1

Region A:
Residues: [1-293]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSILWNLAA FIIALGVLIT VHEFGHFWVA RRCGVRVERF SIGFGKALWR RTDRYGTEYV  60
   61 IALIPLGGYV KMLDERAEPV APELRRHAFN NKTVGQRAAI IAAGPVANFI FAIFAYWLVF 120
  121 IIGVPGVRPV IGEITPNSIA AQAQIAPGTE LKAVDGIETP DWDAVRLQLV SKIGDQQTTV 180
  181 SVAPFGSDQR QDKTLDLRHW AFEPDKQDPV SSLGIRPRGP QIEPVLSEVQ ANSAASKAGL 240
  241 QAGDRIVKVD GQPLTQWMKF VTFVRDNPGK PLALEIERQG SALSLTLTPD TKS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.69897
Match:	1ky9A
Description:	Protease Do (DegP, HtrA), C-terminal domains; Protease Do (DegP, HtrA), catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	2.10639523340529	bayes_pls_golite062009
binding	1.92577219161709	bayes_pls_golite062009
peptidase activity	0.380735225711727	bayes_pls_golite062009
hydrolase activity	0.361589943259802	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.0975384861219175	bayes_pls_golite062009
protein domain specific binding	0.0675941009743699	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [294-376]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNGKAEGFAG VVPKIIPLPE EYKTIRQYGP FSAILEATDK TWQLMKLTVN MLGKLITGDV  60
   61 KLNNLSGPIS IAQGAGMSAE FGV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.0
Match:	1fc6A
Description:	Photosystem II D1 C-terminal processing protease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	2.10639523340529	bayes_pls_golite062009
binding	1.92577219161709	bayes_pls_golite062009
peptidase activity	0.380735225711727	bayes_pls_golite062009
hydrolase activity	0.361589943259802	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.0975384861219175	bayes_pls_golite062009
protein domain specific binding	0.0675941009743699	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [377-450]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IYYLMFLALI SVNLGIINLF PLPVLDGGHL LFLAIEKLKG GPVSERVQDF SYRIGSILLV  60
   61 LLMGLALFND FSRL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: