YRC Public Data Repository - Protein Structure Prediction

Protein:	ASTE_ECOSE
Organism:	Escherichia coli SE11
Length:	322 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASTE_ECOSE.

Description	E-value	Query Range	Subject Range
ASTE_ECOUT - Succinylglutamate desuccinylase OS=Escherichia coli (strain UTI89 / UPEC) GN=astE PE=3 SV=1 gi\|227885831, gi... - gi\|227885831\|ref\|ZP_04003636.1\| succinylglutamate desuccinylase [Escherichia coli 83972], gi\|2278374... gi\|237705694, gi... - gi\|237705694\|ref\|ZP_04536175.1\| succinylglutamate desuccinylase [Escherichia sp. 3_2_53FAA], gi\|2269... ASTE_ECO81 - Succinylglutamate desuccinylase OS=Escherichia coli O81 (strain ED1a) GN=astE PE=3 SV=1 ASTE_ECO45 - Succinylglutamate desuccinylase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=astE PE=3 SV=1 ASTE_ECOK1 - Succinylglutamate desuccinylase OS=Escherichia coli O1:K1 / APEC GN=astE PE=3 SV=1 ASTE_ECOL6 - Succinylglutamate desuccinylase OS=Escherichia coli O6 GN=astE PE=3 SV=1 ASTE_ECOL6 - Succinylglutamate desuccinylase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=as...	283.0	[0..1]	[322..1]
gi\|194418252, gi... - gi\|83569652\|ref\|ZP_00921103.1\| COG2988: Succinylglutamate desuccinylase [Shigella dysenteriae 1012],...	283.0	[0..1]	[322..1]
gi\|15831704, gi\|... - gi\|15831704\|ref\|NP_310477.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. Sakai], ... gi\|189360619, gi... - gi\|189360619\|gb\|EDU79038.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4486], ... gi\|168762187, gi... - gi\|189367516\|gb\|EDU85932.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4501], ... gi\|189356184, gi... - gi\|189356184\|gb\|EDU74603.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4401], ... gi\|188016256, gi... - gi\|188016256\|gb\|EDU54378.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4113], ... gi\|189377555, gi... - gi\|189377555\|gb\|EDU95971.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC508], g... gi\|189371974, gi... - gi\|189371974\|gb\|EDU90390.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC869], g... gi\|168782164, gi... - gi\|189000320\|gb\|EDU69306.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4076], ... gi\|168774952, gi... - gi\|187769385\|gb\|EDU33229.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4196], ... ASTE_ECO57 - Succinylglutamate desuccinylase OS=Escherichia coli O157:H7 GN=astE PE=3 SV=1 gi\|254592762, gi... - gi\|254793362\|ref\|YP_003078199.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. TW14... gi\|12515763, gi\|... - gi\|15802155\|ref\|NP_288177.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 EDL933], gi\|1... gi\|209768602, gi... - pir\|\|F85783 hypothetical protein ydjS [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|208740258, gi... - gi\|208820135\|ref\|ZP_03260455.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC404... gi\|208731176, gi... - gi\|208816833\|ref\|ZP_03257953.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC404... gi\|208725098, gi... - gi\|208810582\|ref\|ZP_03252458.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC420... gi\|195937428 - gi\|195937428\|ref\|ZP_03082810.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC402... gi\|217318041, gi... - gi\|217328694\|ref\|ZP_03444775.1\| succinylglutamate desuccinylase [Escherichia coli O157:H7 str. TW145... ASTE_ECO5E - Succinylglutamate desuccinylase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=astE PE=3 SV=1	283.0	[0..1]	[322..1]
ASTE_ECOL5 - Succinylglutamate desuccinylase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=astE PE=3 SV=1 gi\|190907954, gi... - gi\|75241381\|ref\|ZP_00725232.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli F11], gi\|1...	283.0	[0..1]	[322..1]
gi\|191169571, gi... - gi\|75227071\|ref\|ZP_00713895.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli B7A], gi\|1...	283.0	[0..1]	[322..1]
ASTE_SHIFL - Succinylglutamate desuccinylase OS=Shigella flexneri GN=astE PE=3 SV=1 ASTE_SHIBS - Succinylglutamate desuccinylase OS=Shigella boydii serotype 4 (strain Sb227) GN=astE PE=3 SV=1 gi\|30062989, gi\|... - gi\|30062989\|ref\|NP_837160.1\| succinylglutamate desuccinylase [Shigella flexneri 2a str. 2457T], gi\|3...	283.0	[0..1]	[322..1]
gi\|75256146, gi\|... - gi\|75256146\|ref\|ZP_00727842.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli E22], gi\|1... gi\|75210231, gi\|... - gi\|75210231\|ref\|ZP_00710399.1\| COG2988: Succinylglutamate desuccinylase [Escherichia coli B171], gi\|... ASTE_ECO24 - Succinylglutamate desuccinylase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=astE PE=3 SV...	282.0	[0..1]	[322..1]
ASTE_SHIF8 - Succinylglutamate desuccinylase OS=Shigella flexneri serotype 5b (strain 8401) GN=astE PE=3 SV=1	281.0	[0..1]	[322..1]
ASTE_SHISS - Succinylglutamate desuccinylase OS=Shigella sonnei (strain Ss046) GN=astE PE=3 SV=1	279.0	[0..1]	[322..1]
gi\|62738803, gi\|... - gi\|62738803\|pdb\|1YW6\|B Chain B, Crystal Structure Of Succinylglutamate Desuccinylase From Escherichi...	272.0	[0..2]	[322..7]

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Predicted Domain #1

Region A:
Residues: [1-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNFLALTLT GKKPVITERE INGVRWRWLG DGVLELTPLT PPQGALVISA GIHGNETAPV  60
   61 EMLDALLGAI SHGEIPLRWR LLVILGNPPA LKQGKRYCHS DMNRMFGGRW QLFAESGETC 120
  121 RARELEQCLE DFYDQGKESV RWHLDLHTAI RGSLHPQFGV LPQRDIPWDE KFLTWLGAAG 180
  181 LEALVFHQEP GGTFTHFSAR HFGALACTLE LGKALPFGQN DLRQFAVTAS AIAALLSGES 240
  241 VGIVRTPPLR YRVVSQITRH SPSFEMHMAS DTLNFMPFEK GTLLAQDGEE RFTVTHDVEY 300
  301 VLFPNPLVAL GLRAGLMLEK IS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.221849
Match:	1yw6A
Description:	Crystal Structure of Succinylglutamate Desuccinylase from Escherichia coli, Northeast Structural Genomics Target ET72.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.7824202462173	bayes_pls_golite062009
catalytic activity	1.76936806579991	bayes_pls_golite062009
peptidase activity	1.69812537802871	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	1.41029347724469	bayes_pls_golite062009
exopeptidase activity	0.82896398764377	bayes_pls_golite062009
succinylglutamate desuccinylase activity	0.46025450502966	bayes_pls_golite062009
carboxypeptidase activity	0.215630276604929	bayes_pls_golite062009
N-formylglutamate deformylase activity	0.17769913093601	bayes_pls_golite062009
metallopeptidase activity	0.1586028474273	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: