YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|224501002
Organism:	Listeria monocytogenes FSL R2-561
Length:	331 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|224501002.

Description	E-value	Query Range	Subject Range
gi\|254853323 - gi\|254853323\|ref\|ZP_05242671.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes FSL R2-503] gi\|254825238 - gi\|254825238\|ref\|ZP_05230239.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes FSL J1-194] gi\|254931689 - gi\|254931689\|ref\|ZP_05265048.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes HPB2262] gi\|254878185 - gi\|254878185\|ref\|ZP_05250895.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes FSL J2-071] gi\|255520168 - gi\|255520168\|ref\|ZP_05387405.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes FSL J1-175] SYW_LISMF - Tryptophan--tRNA ligase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=trpS PE=3 SV=1 gi\|47091867, gi\|... - gi\|47091867\|ref\|ZP_00229662.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes str. 4b H7858], ... gi\|153168091, gi... - gi\|153168091\|ref\|ZP_01928122.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes FSL N1-017], gi... gi\|226224806, gi... - gi\|226224806\|ref\|YP_002758913.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes Clip81459], gi...	389.0	[0..1]	[331..1]
SYW_LISIN - Tryptophan--tRNA ligase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=trpS PE=3 SV=1 SYW_LISIN - Tryptophan--tRNA ligase OS=Listeria innocua GN=trpS PE=3 SV=1	387.0	[0..1]	[331..1]
gi\|69288488, gi\|... - gi\|69288488\|ref\|ZP_00618326.1\| Tryptophanyl-tRNA synthetase, class Ib [Kineococcus radiotolerans SRS...	382.0	[0..2]	[330..14]
gi\|56419344, gi\|... - gi\|56419344\|ref\|YP_146662.1\| tryptophanyl-tRNA synthetase [Geobacillus kaustophilus HTA426], gi\|5637...	382.0	[0..1]	[329..1]
SYW_GEOSE - Tryptophan--tRNA ligase OS=Geobacillus stearothermophilus GN=trpS PE=1 SV=1	381.0	[0..1]	[329..1]
SYW_BACHD - Tryptophan--tRNA ligase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 91... SYW_BACHD - Tryptophanyl-tRNA synthetase OS=Bacillus halodurans GN=trpS PE=3 SV=1	380.0	[0..1]	[330..1]
gi\|170709081, gi... - gi\|170709081\|ref\|ZP_02899510.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. A0389], gi\|170... gi\|170686655, gi... - gi\|170686655\|ref\|ZP_02877875.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. A0465], gi\|170... gi\|190559718, gi... - gi\|190569135\|ref\|ZP_03022033.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis Tsiankovskii-I], gi... gi\|172080684, gi... - gi\|177654400\|ref\|ZP_02936297.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. A0174], gi\|172... gi\|21399101, gi\|... - gi\|65318556\|ref\|ZP_00391515.1\| COG0180: Tryptophanyl-tRNA synthetase [Bacillus anthracis str. A2012]... gi\|196031733, gi... - gi\|196037491\|ref\|ZP_03104802.1\| tryptophanyl-tRNA synthetase [Bacillus cereus NVH0597-99], gi\|196031... gi\|47568382, gi\|... - gi\|47568382\|ref\|ZP_00239083.1\| tryptophanyl-tRNA synthetase [Bacillus cereus G9241], gi\|47554930\|gb\|... gi\|196036193, gi... - gi\|196036193\|ref\|ZP_03103592.1\| tryptophanyl-tRNA synthetase [Bacillus cereus W], gi\|195991168\|gb\|ED... gi\|218539613, gi... - gi\|218902377\|ref\|YP_002450211.1\| tryptophanyl-tRNA synthetase [Bacillus cereus AH820], gi\|218539613\|... gi\|164711195, gi... - gi\|165873040\|ref\|ZP_02217660.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. A0488], gi\|164... gi\|167641189, gi... - gi\|167641189\|ref\|ZP_02399443.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. A0193], gi\|167... gi\|167636146, gi... - gi\|167636146\|ref\|ZP_02394451.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. A0442], gi\|167... SYW_BACAN - Tryptophan--tRNA ligase OS=Bacillus anthracis GN=trpS PE=3 SV=1 gi\|225863132, gi... - gi\|225863132\|ref\|YP_002748510.1\| tryptophanyl-tRNA synthetase [Bacillus cereus 03BB102], gi\|22578820... gi\|227003992, gi... - gi\|227815973\|ref\|YP_002815982.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. CDC 684], gi\|... gi\|228913856, gi... - gi\|228913856\|ref\|ZP_04077481.1\| Tryptophanyl-tRNA synthetase [Bacillus thuringiensis serovar pulsien... gi\|228926320, gi... - gi\|228926320\|ref\|ZP_04089393.1\| Tryptophanyl-tRNA synthetase [Bacillus thuringiensis serovar pondich... gi\|228814758, gi... - gi\|228944890\|ref\|ZP_04107252.1\| Tryptophanyl-tRNA synthetase [Bacillus thuringiensis serovar monterr... gi\|228984353, gi... - gi\|228984353\|ref\|ZP_04144533.1\| Tryptophanyl-tRNA synthetase [Bacillus thuringiensis serovar tochigi... gi\|228693106, gi... - gi\|229090224\|ref\|ZP_04221471.1\| Tryptophanyl-tRNA synthetase [Bacillus cereus Rock3-42], gi\|22869310... gi\|229120804, gi... - gi\|229120804\|ref\|ZP_04250046.1\| Tryptophanyl-tRNA synthetase [Bacillus cereus 95/8201], gi\|228662464... gi\|228599894, gi... - gi\|229183484\|ref\|ZP_04310708.1\| Tryptophanyl-tRNA synthetase [Bacillus cereus BGSC 6E1], gi\|22859989... gi\|229264845, gi... - gi\|229600437\|ref\|YP_002865708.1\| tryptophan--tRNA ligase [Bacillus anthracis str. A0248], gi\|2292648... gi\|254682650 - gi\|254682650\|ref\|ZP_05146511.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. CNEVA-9066] gi\|254725445 - gi\|254725445\|ref\|ZP_05187227.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. A1055] gi\|254734068 - gi\|254734068\|ref\|ZP_05191782.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. Western North ... gi\|254740784 - gi\|254740784\|ref\|ZP_05198473.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. Kruger B] gi\|254753627 - gi\|254753627\|ref\|ZP_05205663.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. Vollum] gi\|254758724 - gi\|254758724\|ref\|ZP_05210751.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. Australia 94] gi\|49178046, gi\|... - gi\|49184119\|ref\|YP_027371.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. Sterne], gi\|49178... gi\|47526452, gi\|... - gi\|47526452\|ref\|YP_017801.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. 'Ames Ancestor'],... gi\|30254902, gi\|... - gi\|30261288\|ref\|NP_843665.1\| tryptophanyl-tRNA synthetase [Bacillus anthracis str. Ames], gi\|3025490...	379.0	[0..4]	[330..3]
gi\|89157657, gi\|... - gi\|89204596\|ref\|ZP_01183173.1\| Tryptophanyl-tRNA synthetase, class Ib [Bacillus weihenstephanensis K...	378.0	[0..4]	[330..3]
gi\|152974707, gi... - gi\|89200609\|ref\|ZP_01179361.1\| Tryptophanyl-tRNA synthetase, class Ib [Bacillus cereus subsp. cytoto...	377.0	[0..4]	[330..3]

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Predicted Domain #1

Region A:
Residues: [1-331]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKVIFSGIQ PSGQLTLGNY IGALKQFGQF QDEYECFYCI VDEHAITVPQ DRLKLREQTR  60
   61 SLAALYLAVG LDPEKSTLFI QSEVAAHAQA AWILQCNVYI GELERMTQFK DKSAGKAGVS 120
  121 AGLLTYPPLM AADILLYQTD LVPVGEDQKQ HIELTRDLAE RFNKKHADIF TMPEVFIPKQ 180
  181 GARVMSLQDP TKKMSKSDAN LKNAIFLLDP PATIRKKIKS AVTDSSGIIE YNKEEKPGVS 240
  241 NLLTIYSVIT GETIASIEEK YVGKGYGDFK TDLAELVVSE LEPIQERYYA YLKSEELDTI 300
  301 LDAGAEKAAR VANKTLKKME NGVGLGRKRR K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	106.0
Match:	1i6kA
Description:	Tryptophanyl-tRNA synthetase (TrpRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
tryptophan-tRNA ligase activity	5.34430928486195	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
arginine-tRNA ligase activity	1.50161401062914	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
binding	0.535704308663141	bayes_pls_golite062009
nucleic acid binding	0.449504767632354	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.126511747475258	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: