YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|208728650, gi...
Organism:	Escherichia coli O157:H7 str. EC4206
Length:	513 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|208728650, gi....

Description	E-value	Query Range	Subject Range
gi\|82777881, gi\|... - gi\|82777881\|ref\|YP_404230.1\| exopolyphosphatase [Shigella dysenteriae Sd197], gi\|81242029\|gb\|ABB6273...	480.0	[0..1]	[513..1]
gi\|83570721, gi\|... - gi\|83570721\|ref\|ZP_00922164.1\| COG0248: Exopolyphosphatase [Shigella dysenteriae 1012], gi\|194432122...	480.0	[0..1]	[513..1]
gi\|187731393, gi... - gi\|75178107\|ref\|ZP_00698166.1\| COG0248: Exopolyphosphatase [Shigella boydii BS512], gi\|187731393\|ref... gi\|82544949, gi\|... - gi\|82544949\|ref\|YP_408896.1\| exopolyphosphatase [Shigella boydii Sb227], gi\|81246360\|gb\|ABB67068.1\| ...	480.0	[0..1]	[513..1]
gi\|24113830, gi\|... - gi\|24113830\|ref\|NP_708340.1\| exopolyphosphatase [Shigella flexneri 2a str. 301], gi\|24052920\|gb\|AAN4... gi\|30042131, gi\|... - gi\|30063876\|ref\|NP_838047.1\| exopolyphosphatase [Shigella flexneri 2a str. 2457T], gi\|30042131\|gb\|AA...	480.0	[0..1]	[513..1]
gi\|110344256, gi... - gi\|110642664\|ref\|YP_670394.1\| exopolyphosphatase [Escherichia coli 536], gi\|110344256\|gb\|ABG70493.1\|... gi\|218690617, gi... - gi\|218690617\|ref\|YP_002398829.1\| exopolyphosphatase [Escherichia coli ED1a], gi\|218428181\|emb\|CAR090... gi\|191172938, gi... - gi\|75240140\|ref\|ZP_00724099.1\| COG0248: Exopolyphosphatase [Escherichia coli F11], gi\|191172938\|ref\|...	480.0	[0..1]	[513..1]
gi\|75196510, gi\|... - gi\|75196510\|ref\|ZP_00706580.1\| COG0248: Exopolyphosphatase [Escherichia coli HS], gi\|157161963\|ref\|Y...	480.0	[0..1]	[513..1]
gi\|192958253, gi... - gi\|75237751\|ref\|ZP_00721767.1\| COG0248: Exopolyphosphatase [Escherichia coli E110019], gi\|193068301\|...	479.0	[0..1]	[513..1]
gi\|213864750 - gi\|213864750\|ref\|ZP_03386869.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh... gi\|213647473 - gi\|213647473\|ref\|ZP_03377526.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh... gi\|224582963, gi... - gi\|224582963\|ref\|YP_002636761.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Par... gi\|214002891 - gi\|214002891\|ref\|ZP_03413626.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh... gi\|194450339, gi... - gi\|194450339\|ref\|YP_002046566.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Hei... gi\|168466751, gi... - gi\|195630753\|gb\|EDX49345.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Newport ... gi\|213160884 - gi\|213160884\|ref\|ZP_03346594.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typh... gi\|199604572, gi... - gi\|200387474\|ref\|ZP_03214086.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Virc... gi\|161362107, gi... - gi\|161612743\|ref\|YP_001586708.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Par... PPX_SALTI - Exopolyphosphatase OS=Salmonella typhi GN=ppx PE=3 SV=2 PPX_SALTY - Exopolyphosphatase OS=Salmonella typhimurium GN=ppx PE=3 SV=2 PPX_SALTI - Exopolyphosphatase OS=Salmonella typhi GN=ppx PE=3 SV=2 gi\|238913641 - gi\|238913641\|ref\|ZP_04657478.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Tenn... gi\|29140883, gi\|... - gi\|29140883\|ref\|NP_804225.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typhi s... gi\|16761420 - gi\|16761420\|ref\|NP_457037.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Typhi s... lcl\|NC_016856.1_... - [gene=ppx] [protein=exopolyphosphatase] [protein_id=YP_005238595.1] [location=2668560..2670101] PPX_SALTY - Exopolyphosphatase OS=Salmonella typhimurium GN=ppx PE=3 SV=2 PPX_SALTY - Exopolyphosphatase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=ppx PE=3 SV=2	477.0	[0..1]	[513..1]
gi\|56126872, gi\|... - gi\|56412615\|ref\|YP_149690.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Paratyp... gi\|197361550, gi... - gi\|197361550\|ref\|YP_002141186.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Par...	477.0	[0..1]	[513..1]
gi\|77629846, gi\|... - gi\|77629846\|ref\|ZP_00792432.1\| COG0248: Exopolyphosphatase [Yersinia pseudotuberculosis IP 31758], g... gi\|165937131, gi... - gi\|89104917\|ref\|ZP_01177447.1\| COG0248: Exopolyphosphatase [Yersinia pestis biovar Orientalis str. I... gi\|165926016, gi... - gi\|165926016\|ref\|ZP_02221848.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. F1991016]... gi\|165992796, gi... - gi\|166008414\|ref\|ZP_02229312.1\| exopolyphosphatase [Yersinia pestis biovar Antiqua str. E1979001], g... gi\|166206438, gi... - gi\|166212507\|ref\|ZP_02238542.1\| exopolyphosphatase [Yersinia pestis biovar Antiqua str. B42003004], ... gi\|166960759, gi... - gi\|167421270\|ref\|ZP_02313023.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. MG05-1020... gi\|229681652, gi... - gi\|229901723\|ref\|ZP_04516845.1\| exopolyphosphatase [Yersinia pestis Nepal516], gi\|229681652\|gb\|EEO77... gi\|167056354, gi... - gi\|167424472\|ref\|ZP_02316225.1\| exopolyphosphatase [Yersinia pestis biovar Mediaevalis str. K1973002... Q668D7\|Q668D7_YERPS - Putative exopolyphosphatase - Yersinia pseudotuberculosis gi\|167467165 - gi\|167467165\|ref\|ZP_02331869.1\| exopolyphosphatase [Yersinia pestis FV-1] gi\|149365300, gi... - gi\|149365300\|ref\|ZP_01887335.1\| exopolyphosphatase [Yersinia pestis CA88-4125], gi\|149291713\|gb\|EDM4... gi\|169750119, gi... - gi\|170023585\|ref\|YP_001720090.1\| exopolyphosphatase [Yersinia pseudotuberculosis YPIII], gi\|16975011... gi\|145599461, gi... - gi\|145599461\|ref\|YP_001163537.1\| exopolyphosphatase [Yersinia pestis Pestoides F], gi\|145211157\|gb\|A... gi\|186896210, gi... - gi\|186896210\|ref\|YP_001873322.1\| exopolyphosphatase [Yersinia pseudotuberculosis PB1/+], gi\|18669923... gi\|229694778, gi... - gi\|229838412\|ref\|ZP_04458571.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. PEXU2], g... gi\|229701555, gi... - gi\|229895400\|ref\|ZP_04510572.1\| exopolyphosphatase [Yersinia pestis Pestoides A], gi\|229701555\|gb\|EE... gi\|25290375 - pir\|\|AF0345 probable exopolyphosphatase (EC 3.6.1.11) [imported] - Yersinia pestis (strain CO92) gi\|229898979, gi... - gi\|229898979\|ref\|ZP_04514123.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. India 195... gi\|45437342, gi\|... - gi\|45442477\|ref\|NP_994016.1\| exopolyphosphatase [Yersinia pestis biovar Microtus str. 91001], gi\|454... gi\|22125295, gi\|... - gi\|22125295\|ref\|NP_668718.1\| exopolyphosphatase [Yersinia pestis KIM], gi\|21958171\|gb\|AAM84969.1\|AE0... gi\|218929900, gi... - gi\|218929900\|ref\|YP_002347775.1\| exopolyphosphatase [Yersinia pestis CO92], gi\|16123032\|ref\|NP_40634... gi\|51597119, gi\|... - gi\|51597119\|ref\|YP_071310.1\| exopolyphosphatase [Yersinia pseudotuberculosis IP 32953], gi\|51590401\|...	477.0	[0..1]	[512..1]

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Predicted Domain #1

Region A:
Residues: [1-513]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIHDKSPRP QEFAAVDLGS NSFHMVIARV VDGAMQIIGR LKQRVHLADG LGPDNMLSEE  60
   61 AMTRGLNCLS LFAERLQGFS PASVCIVGTH TLRQALNATD FLKRAEKVIP YPIEIISGNE 120
  121 EARLIFMGVE HTQPEKGRKL VIDIGGGSTE LVIGENFEPI LVESRRMGCV SFAQLYFPGG 180
  181 VINKENFQRA RMAAAQKLET LTWQFRIQGW NVAMGASGTI KAAHEVLMEM GEKDGIITPE 240
  241 RLEKLVKEVL RHRNFASLSL PGLSEERKTV FVPGLAILCG VFDALAIREL RLSDGALREG 300
  301 VLYEMEGRFR HQDVRSRTAS SLANQYHIDS EQARRVLDTT MQMYEQWREQ QPKLAHPQLE 360
  361 ALLRWAAMLH EVGLNINHSG LHRHSAYILQ NSDLPGFNQE QQLMMATLVR YHRKAIKLDD 420
  421 LPRFTLFKKK QFLPLIQLLR LGVLLNNQRQ ATTTPPTLTL ITDDSHWTLR FPHDWFSQNA 480
  481 LVLLDLEKEQ EYWEGVAGWR LKIEEESTPE IAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	136.0
Match:	1u6zA
Description:	Structure of an E. coli Exopolyphosphatase: Insight into the processive hydrolysis of polyphosphate and its regulation
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	1.87760960987608	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.75615325783105	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.59605394946105	bayes_pls_golite062009
binding	1.25460196265758	bayes_pls_golite062009
polyphosphate kinase activity	1.21204737821821	bayes_pls_golite062009
protein binding	1.01732312833155	bayes_pls_golite062009
phosphoric diester hydrolase activity	0.924155015104714	bayes_pls_golite062009
cyclic-nucleotide phosphodiesterase activity	0.641327801104871	bayes_pls_golite062009
transferase activity	0.569421514787167	bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity	0.532800957697682	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
adenyl nucleotide binding	0.232254847278069	bayes_pls_golite062009
ATP binding	0.20090931123533	bayes_pls_golite062009
adenyl ribonucleotide binding	0.164881755458122	bayes_pls_golite062009
protein kinase activity	0.0746500139691637	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: