YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|166212578, gi...
Organism:	Yersinia pestis biovar Antiqua str. B42003004
Length:	164 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|166212578, gi....

Description	E-value	Query Range	Subject Range
ISCR_YERE8 - HTH-type transcriptional regulator IscR OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain... gi\|77976668 - gi\|77976668\|ref\|ZP_00832144.1\| COG1959: Predicted transcriptional regulator [Yersinia intermedia ATC... gi\|238723775, gi... - gi\|77974688\|ref\|ZP_00830227.1\| COG1959: Predicted transcriptional regulator [Yersinia frederiksenii ...	7.0E-50	[1..164]	[1..164]
gi\|45442337, gi\|... - gi\|45442337\|ref\|NP_993876.1\| DNA-binding transcriptional regulator IscR [Yersinia pestis biovar Micr... gi\|186699296, gi... - gi\|186896270\|ref\|YP_001873382.1\| DNA-binding transcriptional regulator IscR [Yersinia pseudotubercul... gi\|169750055, gi... - gi\|170023521\|ref\|YP_001720026.1\| DNA-binding transcriptional regulator IscR [Yersinia pseudotubercul... gi\|21958101, gi\|... - gi\|22125232\|ref\|NP_668655.1\| DNA-binding transcriptional regulator IscR [Yersinia pestis KIM], gi\|21...	9.0E-50	[1..164]	[22..185]
gi\|238765525, gi... - gi\|238765525\|ref\|ZP_04626441.1\| HTH-type transcriptional regulator iscR [Yersinia kristensenii ATCC ... gi\|238719501, gi... - gi\|77963408\|ref\|ZP_00827218.1\| COG1959: Predicted transcriptional regulator [Yersinia mollaretii ATC...	1.0E-49	[1..164]	[1..164]
ISCR_XENNE - HTH-type transcriptional regulator iscR OS=Xenorhabdus nematophilus GN=iscR PE=3 SV=1 ISCR_XENNA - HTH-type transcriptional regulator IscR OS=Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / L...	6.0E-49	[1..164]	[1..164]
ISCR_ERWCT - HTH-type transcriptional regulator iscR OS=Erwinia carotovora subsp. atroseptica GN=iscR PE=3 SV=1 ISCR_PECAS - HTH-type transcriptional regulator IscR OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-...	1.0E-48	[1..164]	[1..164]
ISCR_PHOLL - HTH-type transcriptional regulator IscR OS=Photorhabdus luminescens subsp. laumondii (strain DSM 151... ISCR_PHOLL - HTH-type transcriptional regulator iscR OS=Photorhabdus luminescens subsp. laumondii GN=iscR PE=3 SV...	6.0E-48	[1..163]	[1..163]
ISCR_SODGM - HTH-type transcriptional regulator IscR OS=Sodalis glossinidius (strain morsitans) GN=iscR PE=3 SV=1	8.0E-46	[1..164]	[1..165]
gi\|91190094, gi\|... - gi\|91225151\|ref\|ZP_01260373.1\| hypothetical protein V12G01_13025 [Vibrio alginolyticus 12G01], gi\|91...	1.0E-44	[1..164]	[1..168]
gi\|116186581, gi... - gi\|75857377\|ref\|ZP_00764993.1\| COG1959: Predicted transcriptional regulator [Vibrio sp. Ex25], gi\|11...	2.0E-44	[1..164]	[1..168]
ISCR_VIBPA - HTH-type transcriptional regulator IscR OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 22106... ISCR_VIBPA - HTH-type transcriptional regulator iscR OS=Vibrio parahaemolyticus GN=iscR PE=3 SV=1	3.0E-44	[1..164]	[1..168]

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Predicted Domain #1

Region A:
Residues: [1-164]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLTSKGRYA VTAMLDVALH SQDGPVPLAD ISERQGISLS YLEQLFSRLR KNGLVASVRG  60
   61 PGGGYLLGKD ASAIAVGAVI TAVDESVDAT RCQGKEGCQG GNRCLTHTLW RDLSERISSF 120
  121 LNNITLAELV NNQDILEVAD RQNNDTRRTA NGRPQETINV NLRA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.69897
Match:	1ylfA
Description:	X-ray crystal structure of BC1842 protein from Bacillus cereus, a member of the Rrf2 family of putative transcription regulators.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.98990675336286	bayes_pls_golite062009
DNA binding	3.4273272886116	bayes_pls_golite062009
nucleic acid binding	3.38054693035398	bayes_pls_golite062009
transcription factor activity	2.80110428028438	bayes_pls_golite062009
binding	2.18911933843505	bayes_pls_golite062009
transcription activator activity	0.53294679084865	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
transcription repressor activity	0.513853050429619	bayes_pls_golite062009
protein binding	0.035220363090062	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: