YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|37927075, gi\|...
Organism:	Thermotoga maritima
Length:	306 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|37927075, gi|....

Description	E-value	Query Range	Subject Range
DAPA_BARBK - 4-hydroxy-tetrahydrodipicolinate synthase OS=Bartonella bacilliformis (strain ATCC 35685 / KC583) GN...	376.0	[0..13]	[306..1]
DAPA_THEMA - 4-hydroxy-tetrahydrodipicolinate synthase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 310... DAPA_THEMA - Dihydrodipicolinate synthase OS=Thermotoga maritima GN=dapA PE=1 SV=1	371.0	[0..13]	[306..1]
DAPA_METJA - Dihydrodipicolinate synthase OS=Methanocaldococcus jannaschii GN=dapA PE=1 SV=1 DAPA_METJA - 4-hydroxy-tetrahydrodipicolinate synthase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM ...	370.0	[0..13]	[306..1]
DAPA_AQUAE - Dihydrodipicolinate synthase OS=Aquifex aeolicus GN=dapA PE=1 SV=1 DAPA_AQUAE - 4-hydroxy-tetrahydrodipicolinate synthase OS=Aquifex aeolicus (strain VF5) GN=dapA PE=1 SV=1	369.0	[0..13]	[305..1]
gi\|241906440, gi... - gi\|241906440\|ref\|ZP_04791022.1\| dihydrodipicolinate synthase [Desulfovibrio vulgaris RCH1], gi\|24188... DAPA_DESVV - 4-hydroxy-tetrahydrodipicolinate synthase OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4) GN=... DAPA_DESVH - 4-hydroxy-tetrahydrodipicolinate synthase OS=Desulfovibrio vulgaris (strain Hildenborough / ATCC 295...	368.0	[0..14]	[306..3]
DAPA_GEOUR - 4-hydroxy-tetrahydrodipicolinate synthase OS=Geobacter uraniireducens (strain Rf4) GN=dapA PE=3 SV=1	367.0	[0..13]	[306..1]
gi\|91202476 - gi\|91202476\|emb\|CAJ72115.1\| strongly similar to dihydropicolinate synthase (DHDPS) [Candidatus Kuene...	363.0	[0..13]	[306..1]
gi\|89360868, gi\|... - gi\|89360868\|ref\|ZP_01198685.1\| Dihydrodipicolinate synthase subfamily [Xanthobacter autotrophicus Py...	360.0	[0..14]	[306..104]
DAPA_GEOMG - 4-hydroxy-tetrahydrodipicolinate synthase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / ...	359.0	[0..13]	[306..1]
DAPA_GEOSL - Dihydrodipicolinate synthase OS=Geobacter sulfurreducens GN=dapA PE=3 SV=1 DAPA_GEOSL - 4-hydroxy-tetrahydrodipicolinate synthase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127...	358.0	[0..13]	[306..1]

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Predicted Domain #1

Region A:
Residues: [1-306]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSDKIHHHH HHMFRGVGTA IVTPFKNGEL DLESYERLVR YQLENGVNAL IVLGTTGESP  60
   61 TVNEDEREKL VSRTLEIVDG KIPVIVGAGT NSTEKTLKLV KQAEKLGANG VLVVTPYYNK 120
  121 PTQEGLYQHY KYISERTDLG IVVYNVPGRT GVNVLPETAA RIAADLKNVV GIXEANPDID 180
  181 QIDRTVSLTK QARSDFMVWS GNDDRTFYLL CAGGDGVISV VSNVAPKQMV ELCAEYFSGN 240
  241 LEKSREVHRK LRPLMKALFV ETNPIPVKAA LNLMGFIENE LRLPLVPASE KTVELLRNVL 300
  301 KESGLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	105.0
Match:	1o5kA
Description:	Crystal structure of Dihydrodipicolinate synthase (TM1521) from Thermotoga maritima at 1.80 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.67031204377352	bayes_pls_golite062009
3-deoxy-7-phosphoheptulonate synthase activity	2.02591266233154	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	1.7625405035454	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	1.72893315846141	bayes_pls_golite062009
transaldolase activity	1.38790063456575	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
binding	0.038419829456847	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: