YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|37926514, gi\|...
Organism:	Azotobacter vinelandii
Length:	741 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|37926514, gi|....

Description	E-value	Query Range	Subject Range
IDH_AZOVI - Isocitrate dehydrogenase [NADP] OS=Azotobacter vinelandii GN=icd PE=1 SV=5	1530.0	[0..1]	[741..1]
gi\|113888624, gi... - gi\|78690436\|ref\|ZP_00855082.1\| Isocitrate dehydrogenase NADP-dependent, monomeric type [Shewanella s...	1512.0	[0..2]	[737..4]
gi\|117612529, gi... - gi\|78685739\|ref\|ZP_00850515.1\| Isocitrate dehydrogenase NADP-dependent, monomeric type [Shewanella s...	1512.0	[0..2]	[737..4]
gi\|39996565, gi\|... - gi\|39996565\|ref\|NP_952516.1\| isocitrate dehydrogenase, NADP-dependent [Geobacter sulfurreducens PCA]...	1511.0	[0..1]	[740..1]
gi\|113530366, gi... - gi\|116695867\|ref\|YP_841443.1\| isocitrate dehydrogenase [NADP] [Ralstonia eutropha H16], gi\|113530366...	1509.0	[0..1]	[740..1]
gi\|82406036, gi\|... - gi\|82495995\|ref\|ZP_00881567.1\| Isocitrate dehydrogenase NADP-dependent, monomeric type [Shewanella s...	1508.0	[0..2]	[737..4]
gi\|34499119, gi\|... - gi\|34499119\|ref\|NP_903334.1\| isocitrate dehydrogenase (NADP) [Chromobacterium violaceum ATCC 12472],...	1508.0	[0..4]	[740..6]
gi\|91229060, gi\|... - gi\|91229060\|ref\|ZP_01262886.1\| isocitrate dehydrogenase [Vibrio alginolyticus 12G01], gi\|91187453\|gb...	1506.0	[0..4]	[739..6]
gi\|78367999, gi\|... - gi\|78367999\|ref\|ZP_00838254.1\| Isocitrate dehydrogenase NADP-dependent, monomeric type [Shewanella s...	1504.0	[0..3]	[738..4]
gi\|194562601, gi... - gi\|84362672\|ref\|ZP_00987288.1\| COG2838: Monomeric isocitrate dehydrogenase [Burkholderia dolosa AUO1...	1504.0	[0..2]	[741..3]

Back

Predicted Domain #1

Region A:
Residues: [1-741]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTPKIIYTL TDEAPALATY SLLPIIKAFT GSSGIAVETR DISLAGRLIA TFPEYLTDTQ  60
   61 KISDDLAELG KLATTPDANI IKLPNISASV PQLKAAIKEL QQQGYKLPDY PEEPKTDTEK 120
  121 DVKARYDKIK GSAVNPVLRE GNSDRRAPLS VKNYARKHPH KMGAWSADSK SHVAHMDNGD 180
  181 FYGSEKAALI GAPGSVKIEL IAKDGSSTVL KAKTSVQAGE IIDSSVMSKN ALRNFIAAEI 240
  241 EDAKKQGVLL SVHLKATMMK VSDPIMFGQI VSEFYKDALT KHAEVLKQIG FDVNNGIGDL 300
  301 YARIKTLPEA KQKEIEADIQ AVYAQRPQLA MVNSDKGITN LHVPSDVIVD ASMPAMIRDS 360
  361 GKMWGPDGKL HDTKAVIPDR CYAGVYQVVI EDCKQHGAFD PTTMGSVPNV GLMAQKAEEY 420
  421 GSHDKTFQIP ADGVVRVTDE SGKLLLEQSV EAGDIWRMCQ AKDAPIQDWV KLAVNRARAT 480
  481 NTPAVFWLDP ARAHDAQVIA KVERYLKDYD TSGLDIRILS PVEATRFSLA RIREGKDTIS 540
  541 VTGNVLRDYL TDLFPIMELG TSAKMLSIVP LMSGGGLFET GAGGSAPKHV QQFLEEGYLR 600
  601 WDSLGEFLAL AASLEHLGNA YKNPKALVLA STLDQATGKI LDNNKSPARK VGEIDNRGSH 660
  661 FYLALYWAQA LAAQTEDKEL QAQFTGIAKA LTDNETKIVG ELAAAQGKPV DIAGYYHPNT 720
  721 DLTSKAMRPS ATFNAALAPL A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1itwA
Description:	Monomeric isocitrate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
isocitrate dehydrogenase activity	3.62126393776639	bayes_pls_golite062009
catalytic activity	3.08295953338337	bayes_pls_golite062009
oxidoreductase activity	2.6468198750213	bayes_pls_golite062009
isocitrate dehydrogenase (NADP+) activity	2.29271552032599	bayes_pls_golite062009
isocitrate dehydrogenase (NAD+) activity	2.10234418832459	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47802406005381	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.44962743981001	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: