YRC Public Data Repository - Protein Structure Prediction

Protein:	LYS9_MAGGR
Organism:	Magnaporthe grisea
Length:	450 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LYS9_MAGGR.

Description	E-value	Query Range	Subject Range
gi\|70993696, gi\|... - gi\|70993696\|ref\|XP_751695.1\| saccharopine dehydrogenase Lys9 [Aspergillus fumigatus Af293], gi\|66849... gi\|159125383 - gi\|159125383\|gb\|EDP50500.1\| saccharopine dehydrogenase [Aspergillus fumigatus A1163]	407.0	[0..1]	[449..5]
gi\|49096556, gi\|... - gi\|67538862\|ref\|XP_663205.1\| hypothetical protein AN5601.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	401.0	[0..1]	[449..5]
gi\|169771431 - gi\|169771431\|ref\|XP_001820185.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|220699124, gi... - gi\|238486014\|ref\|XP_002374245.1\| saccharopine dehydrogenase Lys9, putative [Aspergillus flavus NRRL3... gi\|83768044 - gi\|83768044\|dbj\|BAE58183.1\| unnamed protein product [Aspergillus oryzae]	400.0	[0..2]	[449..6]
LYS9_MAGGR - Saccharopine dehydrogenase [NADP+, L-glutamate-forming] (EC 1.5.1.10) (Saccharopine reductase) - Mag...	389.0	[0..1]	[450..1]
gi\|32404874, gi\|... - gi\|32404874\|ref\|XP_323050.1\| hypothetical protein [Neurospora crassa], gi\|28922634\|gb\|EAA31859.1\| hy... gi\|85101163 - gi\|85101163\|ref\|XP_961095.1\| hypothetical protein [Neurospora crassa OR74A]	386.0	[0..5]	[450..82]
gi\|51013871 - gi\|51013871\|gb\|AAT93229.1\| YNR050C [Saccharomyces cerevisiae]	385.0	[0..3]	[450..2]
gi\|88183139, gi\|... - gi\|88183139\|gb\|EAQ90607.1\| conserved hypothetical protein [Chaetomium globosum CBS 148.51], gi\|11620...	383.0	[0..2]	[450..3]
gi\|164426869, gi... - gi\|164426869\|ref\|XP_961095.2\| saccharopine dehydrogenase [Neurospora crassa OR74A], gi\|157071510\|gb\|... gi\|12718328 - gi\|12718328\|emb\|CAC28679.1\| probable saccharopine reductase [Neurospora crassa]	382.0	[0..2]	[450..3]

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Predicted Domain #1

Region A:
Residues: [1-450]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKSVLMLG SGFVTRPTLD VLTDSGIKVT VACRTLESAK KLSAGVQHST PISLDVNDDA  60
   61 ALDAEVAKHD LVISLIPYTF HATVIKSAIR QKKHVVTTSY VSPAMMELDQ AAKDAGITVM 120
  121 NEIGLDPGID HLYAIKTIEE VHAAGGKIKT FLSYCGGLPA PESSDNPLGY KFSWSSRGVL 180
  181 LALRNAASFY KDGKVTNVAG PELMATAKPY FIYPGFAFVA YPNRDSTPYK ERYQIPEADN 240
  241 IVRGTLRYQG FPQFIKVLVD IGFLSDEEQP FLKEAIPWKE ATQKIVKASS ASEQDIVSTI 300
  301 VSNATFESTE EQKRIVAGLK WLGIFSDKKI TPRGNALDTL CATLEEKMQF EEGERDLVML 360
  361 QHKFEIENKD GSRETRTSSL CEYGAPIGSG GYSAMAKLVG VPCAVAVKFV LDGTISDRGV 420
  421 LAPMNSKIND PLMKELKEKY GIECKEKVVA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	109.0
Match:	1e5lA
Description:	Saccharopine reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	2.60548927745815	bayes_pls_golite062009
catalytic activity	2.54843319568228	bayes_pls_golite062009
saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity	1.89672971172725	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.54909195188343	bayes_pls_golite062009
transcription regulator activity	0.869164731705222	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	0.841370849960815	bayes_pls_golite062009
DNA binding	0.652732293077214	bayes_pls_golite062009
nucleic acid binding	0.614071082278083	bayes_pls_golite062009
binding	0.581256596374241	bayes_pls_golite062009
saccharopine dehydrogenase activity	0.495113665163626	bayes_pls_golite062009
structural molecule activity	0.345975336806588	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.0651785123513661	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: