YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|28373429, gi\|...
Organism:	Homo sapiens
Length:	73 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|28373429, gi|....

Description	E-value	Query Range	Subject Range
gi\|114674895 - gi\|114674895\|ref\|XP_512314.2\| PREDICTED: general transcription factor IIF, polypeptide 1, 74kDa [Pan...	123.0	[0..4]	[73..448]
gi\|21430981 - gi\|21430981\|gb\|AAM49800.1\| RAP74 subunit of transcription factor IIF [Xenopus laevis]	123.0	[0..4]	[73..455]
gi\|73987252 - gi\|73987252\|ref\|XP_533935.2\| PREDICTED: similar to Transcription initiation factor IIF alpha subunit...	122.0	[0..4]	[73..548]
gi\|4504197, gi\|2... - gi\|4504197\|ref\|NP_002087.1\| general transcription factor IIF, polypeptide 1, 74kDa [Homo sapiens], g...	122.0	[0..5]	[73..449]
gi\|109123096 - gi\|109123096\|ref\|XP_001087325.1\| PREDICTED: general transcription factor IIF, polypeptide 1, 74kDa [...	122.0	[0..4]	[73..448]
gi\|61372356, gi\|... - gi\|61372356\|gb\|AAX43829.1\| general transcription factor IIF polypeptide 1 [synthetic construct], gi\|...	122.0	[0..5]	[73..449]
T2FA_BOVIN - General transcription factor IIF subunit 1 OS=Bos taurus GN=GTF2F1 PE=2 SV=1	121.0	[0..4]	[73..448]

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Predicted Domain #1

Region A:
Residues: [1-73]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPLGSGDVQV TEDAVRRYLT RKPMTTKDLL KKFQTKKTGL SSEQTVNVLA QILKRLNPER  60
   61 KMINDKMHFS LKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.522879
Match:	1i27A
Description:	C-terminal domain of the rap74 subunit of TFIIF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.835523092977445	bayes_pls_golite062009
transcription regulator activity	0.4843036104266	bayes_pls_golite062009
nucleic acid binding	0.37117756729668	bayes_pls_golite062009
DNA binding	0.3118855114645	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: