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View Structure Prediction Details

Protein: ANM15_ARATH
Organism: Arabidopsis thaliana
Length: 642 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ANM15_ARATH.

Description E-value Query
Range		 Subject
Range
gi|7270014, gi|7... - pir||T10666 hypothetical protein F6E21.40 - Arabidopsis thaliana, gi|7270014|emb|CAB79830.1| kinase ...
 600.0 [0..1] [642..1]

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Predicted Domain #1
Region A:
Residues: [1-164] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLGERGGWE RTESRYCGVE TDFSNDVTHL LNFNISTGGF DYVLAPLVDP SYRPSLVEGN  60
   61 GVDTQVLPVC GSDLVLSPSQ WSSHVVGKIS SWIDLDSEDE VLRMDSETTL KQEIAWATHL 120
  121 SLQACLLPTP KGKSCANYAR CVNQILQGLT TLQLWLRVPL VKSE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [165-265] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDSMDDTSEG LNDSWELWNS FRLLCEHDSK LSVALDVLST LPSETSLGRW MGESVRAAIL  60
   61 STDAFLTNAR GYPCLSKRHQ KLIAGFFDHA AQVVICGKPV H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.154902
Match: 1wxwA
Description: Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [266-642] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLQKPLDSSS EGTEKNPLRI YLDYVAYLFQ KMESLSEQER IELGYRDFLQ APLQPLMDNL  60
   61 EAQTYETFER DSVKYIQYQR AVEKALVDRV PDEKASELTT VLMVVGAGRG PLVRASLQAA 120
  121 EETDRKLKVY AVEKNPNAVV TLHNLVKMEG WEDVVTIISC DMRFWNAPEQ ADILVSELLG 180
  181 SFGDNELSPE CLDGAQRFLK PDGISIPSSY TSFIQPITAS KLYNDVKAHK DLAHFETAYV 240
  241 VKLHSVAKLA PSQSVFTFTH PNFSTKVNNQ RYKKLQFSLP SDAGSALVHG FAGYFDSVLY 300
  301 KDVHLGIEPT TATPNMFSWF PIFFPLRKPV EVHPDTPLEV HFWRCCGSSK VWYEWSVSSP 360
  361 TPSPMHNTNG RSYWVGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.69897
Match: 1orhA
Description: Structure of the Predominant Protein Arginine Methyltransferase PRMT1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein-arginine N-methyltransferase activity 5.52520020727046 bayes_pls_golite062009
arginine N-methyltransferase activity 5.52520020727046 bayes_pls_golite062009
protein methyltransferase activity 5.03267617653315 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 4.4632173842967 bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific) 4.42061797259061 bayes_pls_golite062009
histone methyltransferase activity 4.40911163698179 bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity 4.39379274790202 bayes_pls_golite062009
methyltransferase activity 4.15445027778357 bayes_pls_golite062009
N-methyltransferase activity 4.07806017452628 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 4.07153733729662 bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity 3.55785970363721 bayes_pls_golite062009
histone-arginine N-methyltransferase activity 2.86617323549909 bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity 2.80855981068149 bayes_pls_golite062009
transferase activity 2.22303238506686 bayes_pls_golite062009
DNA-methyltransferase activity 2.18991764495147 bayes_pls_golite062009
RNA methyltransferase activity 1.86200407013263 bayes_pls_golite062009
rRNA methyltransferase activity 1.79395300104934 bayes_pls_golite062009
histone methyltransferase activity (H2A-R3 specific) 1.49229188826344 bayes_pls_golite062009
[myelin basic protein]-arginine N-methyltransferase activity 1.49229188826344 bayes_pls_golite062009
histone methyltransferase activity (H3-R2 specific) 1.49229188826344 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
RNA binding 1.10729923226801 bayes_pls_golite062009
binding 0.976078016260105 bayes_pls_golite062009
histone binding 0.964746527369069 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
tRNA methyltransferase activity 0.868107614027708 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
lysine N-methyltransferase activity 0.858129308056814 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 0.858129308056814 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 0.858129308056814 bayes_pls_golite062009
mRNA methyltransferase activity 0.73490663449605 bayes_pls_golite062009
mRNA (guanine-N7-)-methyltransferase activity 0.73490663449605 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 0.703178429468566 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 0.102141401712309 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.0251895714734512 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle