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View Structure Prediction Details

Protein: LOX5_ARATH
Organism: Arabidopsis thaliana
Length: 886 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LOX5_ARATH.

Description E-value Query
Range
Subject
Range
gi|899344, gi|21... - gi|899344|emb|CAA58859.1| lipoxygenase [Nicotiana tabacum], pir||S57964 lipoxygenase (EC 1.13.11.12)...
1376.0 [0..20] [886..4]

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Predicted Domain #1
Region A:
Residues: [1-886]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIHTDIAEIL CVKPKTTKKT KTMEEDVKKT TTMKIEGEVV VMKKNLLDFK DVMASLLDRV  60
   61 NELLGRRVSL HLISSHQPDP ANEKRGRLGK AAHLEKWVTK IKTSVTAEET AFGVTFDWDE 120
  121 SMGPPAAFVI KNHHHSQFYL KSLTLRGFPD GEGGATAIHF ICNSWIYPNH RYRSDRVFFS 180
  181 NKAYLPSETP ELIKELREEE LKNLRGNEKG GEFKEWDRVY DYAYYNDLGA PDKGPDSVRP 240
  241 VLGGSPELPY PRRGKTGRKS TKSDPKSESR LALLNLNIYV PRDERFSHVK FSDFLAYALK 300
  301 SVTQVLVPEI ASVCDKTINE FDSFEDVFHL YDGSIKLANG HTISKLRDVI PWEMFRELVR 360
  361 NDGERFLKYP LPDILKESRS AWRTDEEFAR EMLAGLNPVV ISRLQEFPPK SCLDSAKYGN 420
  421 QHSSIRTEHI ESNMNGLNVQ EALEQNKLYI LDHHDALMPY LTRINSTNTK TYATRTLLLL 480
  481 QADGTLKPLA IELSLPHAQG ESYGSVSKVF TPAEKGVEGS VWQLAKAYAA VNDSGYHQLI 540
  541 SHWLQTHAVI EPFIIASNRQ LSVVHPIHKL LHPHFRDTMN INALARHVLI NSDGVLERTV 600
  601 FPSRYAMEMS SSIYKNWVFT EQALPKDLLK RGVAVEDPNS DNGVKLLIED YPFAVDGLEI 660
  661 WSAIKTWVTE YCTFYYNNDK TVQTDTEIQS WWTELRTKGH GDKRHESWWP SMQTRDDLIE 720
  721 TCTIIIWIAS ALHAAVNFGQ YPYAGFLPNR PTVSRRFMPE PGTDEYAELE EDADVAFLKT 780
  781 ITPQLQTLLG ISIIEILSMH STDEIYLGQR DSPNWTADDE PLEAFKRFGK ELELIENNII 840
  841 RRNNDKRFKN RTGPVNIPYT LLYPNTTDYT REGGITGKGI PNSVSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1hu9A
Description: Lipoxigenase, C-terminal domain; Plant lipoxigenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
arachidonate 5-lipoxygenase activity 8.44515061433916 bayes_pls_golite062009
arachidonate 12-lipoxygenase activity 6.08213265273158 bayes_pls_golite062009
hepoxilin-epoxide hydrolase activity 4.96120669616017 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3.68734614042811 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3.61969258161886 bayes_pls_golite062009
dioxygenase activity 3.30721216596384 bayes_pls_golite062009
binding 1.8976030946043 bayes_pls_golite062009
protein binding 1.53930087292625 bayes_pls_golite062009
catalytic activity 1.04649784555215 bayes_pls_golite062009
arachidonate 15-lipoxygenase activity 0.440928568408097 bayes_pls_golite062009
ether hydrolase activity 0.0770523899606701 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle