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View Structure Prediction Details

Protein: gi|241913083, gi...
Organism: Homo sapiens
Length: 133 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|241913083, gi....

Description E-value Query
Range		 Subject
Range
RNAS1_MUSSA - Ribonuclease pancreatic OS=Mus saxicola GN=Rnase1 PE=2 SV=1
 190.0 [0..3] [133..25]
RNS1A_RATEX - Ribonuclease pancreatic alpha-type OS=Rattus exulans PE=3 SV=1
 190.0 [0..3] [133..25]
gi|387884 - gi|387884|gb|AAA72757.1| RNase A [synthetic construct]
 190.0 [0..3] [133..32]
gi|26344600, gi|... - gi|31981520|ref|NP_035401.2| pancreatic ribonuclease [Mus musculus], gi|26344600|dbj|BAC35949.1| unn...
 189.0 [0..3] [133..25]
RNAS1_LEMCA - Ribonuclease pancreatic OS=Lemur catta GN=RNASE1 PE=3 SV=1
 188.0 [0..3] [133..28]
RNAS1_LAGLA - Ribonuclease pancreatic OS=Lagothrix lagotricha GN=RNASE1 PE=3 SV=1
 188.0 [0..3] [133..28]
gi|71361661, gi|... - gi|71361661|ref|NP_001025075.1| ribonuclease, RNase A family, 1 (pancreatic) [Rattus norvegicus], re...
 186.0 [0..4] [133..29]
gi|18376502 - gi|18376502|emb|CAC86435.1| pancreatic ribonuclease alpha [Berylmys bowersi]
 186.0 [0..3] [132..25]
RNAS1_URARU - Ribonuclease pancreatic OS=Uranomys ruddi GN=RNASE1 PE=2 SV=1
 186.0 [0..4] [133..26]
RNAS1_HORSE - Ribonuclease pancreatic OS=Equus caballus GN=RNASE1 PE=1 SV=1
 185.0 [0..4] [133..1]

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Predicted Domain #1
Region A:
Residues: [1-133] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPPQFTRAQW FAIQHISLNP PRCTIAMRAI NNYRWRCKNQ NTFLRTTFAN VVNVCGNQSI  60
   61 RCPHNRTLNN CHRSRFRVPL LHCDLINPGA QNISNCRYAD RPGRRFYVVA CDNRDPRDSP 120
  121 RYPVVPVHLD TTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.69897
Match: 1h1hA
Description: Eosinophil cationic protein (ECP), ribonuclease 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 5.90974666963628 bayes_pls_golite062009
receptor binding 3.72281739209072 bayes_pls_golite062009
heparin binding 3.58380117228366 bayes_pls_golite062009
glycosaminoglycan binding 3.52657253958322 bayes_pls_golite062009
pattern binding 3.51086739633778 bayes_pls_golite062009
polysaccharide binding 3.37691389332571 bayes_pls_golite062009
carbohydrate binding 2.92080685971777 bayes_pls_golite062009
hydrolase activity 2.70113793821942 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.58556100530058 bayes_pls_golite062009
copper ion binding 2.3834238539949 bayes_pls_golite062009
nuclease activity 2.14644364712282 bayes_pls_golite062009
catalytic activity 1.25983854650131 bayes_pls_golite062009
binding 0.96196363528423 bayes_pls_golite062009
transition metal ion binding 0.840957518206308 bayes_pls_golite062009
protein binding 0.625034293323203 bayes_pls_golite062009
endoribonuclease activity 0.390109603204743 bayes_pls_golite062009
nucleic acid binding 0.166558045469459 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle