YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7546531, gi\|7...
Organism:	Escherichia coli
Length:	265 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7546531, gi|7....

Description	E-value	Query Range	Subject Range
gi\|37200667, gi\|... - gi\|37676126\|ref\|NP_936522.1\| transcriptional regulator [Vibrio vulnificus YJ016], gi\|37200667\|dbj\|BA...	159.0	[0..18]	[219..1]
gi\|27367995, gi\|... - gi\|27367995\|ref\|NP_763522.1\| transcriptional regulator [Vibrio vulnificus CMCP6], gi\|27359568\|gb\|AAO...	158.0	[0..18]	[219..1]
gi\|90327975, gi\|... - gi\|90411129\|ref\|ZP_01219142.1\| transcriptional regulator, LysR family protein [Photobacterium profun...	158.0	[0..20]	[219..1]
gi\|87118407, gi\|... - gi\|87118407\|ref\|ZP_01074306.1\| putative transcription regulator protein [Marinomonas sp. MED121], gi...	157.0	[0..19]	[216..1]
gi\|28900071, gi\|... - gi\|28900071\|ref\|NP_799726.1\| putative transcription regulator protein [Vibrio parahaemolyticus RIMD ... gi\|28808354 - gi\|28808354\|dbj\|BAC61559.1\| putative transcription regulator protein [Vibrio parahaemolyticus RIMD 2...	156.0	[0..25]	[219..7]
gi\|94500932, gi\|... - gi\|94500932\|ref\|ZP_01307457.1\| transcriptional regulator, LysR family protein [Oceanobacter sp. RED6...	156.0	[0..20]	[264..4]
gi\|91191158, gi\|... - gi\|91224247\|ref\|ZP_01259510.1\| putative transcription regulator protein [Vibrio alginolyticus 12G01]...	155.0	[0..25]	[219..7]
gi\|116185384, gi... - gi\|75856032\|ref\|ZP_00763668.1\| COG0583: Transcriptional regulator [Vibrio sp. Ex25], gi\|254227935\|re...	155.0	[0..25]	[219..7]
gi\|90440322, gi\|... - gi\|90577236\|ref\|ZP_01233047.1\| putative transcriptional regulator, LysR family protein [Vibrio angus...	154.0	[0..19]	[219..1]
gi\|15074499 - gi\|15074499\|emb\|CAC46145.1\| Transcription regulator LysR family [Sinorhizobium meliloti 1021] gi\|15965319 - gi\|15965319\|ref\|NP_385672.1\| putative transcription regulator protein [Sinorhizobium meliloti 1021]	154.0	[0..15]	[216..2]

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Predicted Domain #1

Region A:
Residues: [1-265]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSHXQAEILL TLKLQQKLFA DPRRISLLKH IALSGSISQG AKDAGISYKS AWDAINEXNQ  60
   61 LSEHILVERA TGGKGGGGAV LTRYGQRLIQ LYDLLAQIQQ KAFDVLSDDD ALPLNSLLAA 120
  121 ISRFSLQTSA RNQWFGTITA RDHDDVQQHV DVLLADGKTR LKVAITAQSG ARLGLDEGKE 180
  181 VLILLKAPWV GITQDEAVAQ NADNQLPGII SHIERGAEQC EVLXALPDGQ TLCATVPVNE 240
  241 ATSLQQGQNV TAYFNADSVI IATLC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.69897
Match:	1b9mA
Description:	N-terminal domain of molybdate-dependent transcriptional regulator ModE; C-terminal domain of molybdate-dependent transcriptional regulator ModE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
molybdenum ion binding	2.306486700841	bayes_pls_golite062009
transcription regulator activity	1.3574186068153	bayes_pls_golite062009
nucleic acid binding	1.03033432349652	bayes_pls_golite062009
DNA binding	0.926753986189559	bayes_pls_golite062009
binding	0.731921702708422	bayes_pls_golite062009
transcription factor activity	0.638085164477305	bayes_pls_golite062009
transcription activator activity	0.53294679084865	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
transcription repressor activity	0.513853050429619	bayes_pls_golite062009
transporter activity	0.437297481147526	bayes_pls_golite062009
protein binding	0.035220363090062	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: