YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|6730263, gi\|6...
Organism:	Saccharomyces cerevisiae
Length:	311 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|6730263, gi|6....

Description	E-value	Query Range	Subject Range
gi\|151942573 - gi\|151942573\|gb\|EDN60919.1\| RNA 5'-triphosphatase [Saccharomyces cerevisiae YJM789] gi\|190407736 - gi\|190407736\|gb\|EDV11001.1\| RNA 5'-triphosphatase [Saccharomyces cerevisiae RM11-1a] gi\|3121838, gi\|2... - gi\|3121838\|sp\|O13297.1\|CET1_YEAST RecName: Full=mRNA-capping enzyme subunit beta; AltName: Full=Poly... gi\|207340731 - gi\|207340731\|gb\|EDZ68989.1\| YPL228Wp-like protein [Saccharomyces cerevisiae AWRI1631]	400.0	[0..3]	[311..241]
CET1_ASHGO - mRNA-capping enzyme subunit beta OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NR... CET1_ASHGO - mRNA-capping enzyme subunit beta OS=Ashbya gossypii GN=CET1 PE=3 SV=1	368.0	[0..3]	[311..169]
CET1_CANGA - mRNA-capping enzyme subunit beta OS=Candida glabrata GN=CET1 PE=3 SV=1 CET1_CANGA - mRNA-capping enzyme subunit beta OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0...	366.0	[0..3]	[310..294]
CET1_KLULA - mRNA-capping enzyme subunit beta OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / ... CET1_KLULA - mRNA-capping enzyme subunit beta OS=Kluyveromyces lactis GN=CET1 PE=3 SV=1	364.0	[0..3]	[310..244]
gi\|49087900, gi\|... - gi\|67522481\|ref\|XP_659301.1\| hypothetical protein AN1697.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	313.0	[0..5]	[298..441]
gi\|159125112 - gi\|159125112\|gb\|EDP50229.1\| mRNA capping nucleoside-triphosphatase, putative [Aspergillus fumigatus ... gi\|66849609, gi\|... - gi\|70994268\|ref\|XP_751975.1\| mRNA capping nucleoside-triphosphatase [Aspergillus fumigatus Af293], g...	310.0	[0..5]	[297..472]
gi\|114192717, gi... - gi\|115397869\|ref\|XP_001214526.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	302.0	[0..5]	[298..446]
gi\|83769084 - gi\|83769084\|dbj\|BAE59221.1\| unnamed protein product [Aspergillus oryzae] gi\|169773509 - gi\|169773509\|ref\|XP_001821223.1\| hypothetical protein [Aspergillus oryzae RIB40]	300.0	[0..29]	[297..453]
gi\|90300482, gi\|... - gi\|90300482\|gb\|EAS30113.1\| hypothetical protein CIMG_08859 [Coccidioides immitis RS], gi\|119180461\|r...	293.0	[0..29]	[297..508]

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Predicted Domain #1

Region A:
Residues: [1-311]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HMYRNVPIWA QKWKPTIKAL QSINVKDLKI DPSFLNIIPD DDLTKSVQDW VYATIYSIAP  60
   61 ELRSFIELEM KFGVIIDAKG PDRVNPPVSS QCVFTELDAH LTPNIDASLF KELSKYIRGI 120
  121 SEVTENTGKF SIIESQTRDS VYRVGLSTQR PRFLRMSTDI KTGRVGQFIE KRHVAQLLLY 180
  181 SPKDSYDVKI SLNLELPVPD NDPPEKYKSQ SPISERTKDR VSYIHNDSCT RIDITKVENH 240
  241 NQNSKSRQSE TTHEVELEIN TPALLNAFDN ITNDSKEYAS LIRTFLNNGT IIRRKLSSLS 300
  301 YEIFEGSKKV M

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	114.0
Match:	1d8hA
Description:	mRNA triphosphatase CET1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
polynucleotide 5'-phosphatase activity	11.2864202061301	bayes_pls_golite062009
nucleotide phosphatase activity	5.10806075014632	bayes_pls_golite062009
binding	1.32114964285132	bayes_pls_golite062009
catalytic activity	1.17990683373825	bayes_pls_golite062009
hydrolase activity	0.487109994827608	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: