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View Structure Prediction Details

Protein: gi|2392269, gi|2...
Organism: Rattus norvegicus
Length: 624 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2392269, gi|2....

Description E-value Query
Range
Subject
Range
gi|1942317, gi|1... - gi|1942320|pdb|1QAT|B Chain B, 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Delta Compl...
600.0 [0..3] [624..1]
gi|149018286 - gi|149018286|gb|EDL76927.1| phospholipase C, delta 1 [Rattus norvegicus]
gi|30352160 - gi|30352160|gb|AAP31521.1| phospholipase C delta [Rattus sp.]
584.0 [0..1] [624..133]
PLCD1_BOVIN, PID... - 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 - Bos taurus (Bovine), (P10895) 1-...
582.0 [0..1] [624..72]
PLCD1_MOUSE - 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 OS=Mus musculus GN=Plcd1 PE=1 SV=2
gi|117616624 - gi|117616624|gb|ABK42330.1| PLC-delta1 [synthetic construct]
580.0 [0..1] [624..133]
gi|2137061, gi|1... - pir||PC4183 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (EC 3.1.4.11) delta-1 - Chine...
580.0 [0..1] [624..122]
gi|62089310 - gi|62089310|dbj|BAD93099.1| Phospholipase C, delta 1 variant [Homo sapiens]
575.0 [0..1] [624..153]
PLCD4_PIG - 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 OS=Sus scrofa GN=PLCD4 PE=2 SV=1
574.0 [0..2] [624..135]

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Predicted Domain #1
Region A:
Residues: [1-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSMDQRQKLQ HWIHSCLRKA DKNKDNKMNF KELKDFLKEL NIQVDDGYAR KIFRECDHSQ  60
   61 TDSLEDEEIE TFYKMLTQRA EIDRAFEEAA GSAETLSVER LVTFLQHQQR EEEAGPALAL 120
  121 SLIERYEPSE TAKAQRQMTK DGFLMYLLSA DGNAFSLAHR RVYQDMDQPL SHYLVSSSHN 180
  181 TYLLEDQLTG PSSTEAYIRA LCKGCRCLEL DCWDGPNQEP IIYHGYTFTS KILFCDVLRA 240
  241 IRDYAFKASP YPVILSLENH CSLEQQRVMA RHLRAILGPI LLDQPLDGVT TSLPSPEQLK 300
  301 GKILLKGKKL GGLLPAGGEN GSEATDVSDE VEAAEMEDEA VRSQVQHKPK EDKLKLVPEL 360
  361 SDMIIYCKSV HFGGFSSPGT SGQAFYEMAS FSESRALRLL QESGNGFVRH NVSCLSRIYP 420
  421 AGWRTDSSNY SPVEMWNGGC QIVALNFQTP GPEMDVYLGC FQDNGGCGYV LKPAFLRDPN 480
  481 TTFNSRALTQ GPWWRPERLR VRIISGQQLP KVNKNKNSIV DPKVIVEIHG VGRDTGSRQT 540
  541 AVITNNGFNP RWDMEFEFEV TVPDLALVRF MVEDYDSSSK NDFIGQSTIP WNSLKQGYRH 600
  601 VHLLSKNGDQ HPSATLFVKI SIQD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 173.0
Match: 1djgA
Description: Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!); PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain; Phospholipase C isozyme D1 (PLC-D1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipase C activity 1.68837208308012 bayes_pls_golite062009
hydrolase activity 1.21781019708396 bayes_pls_golite062009
phosphoric diester hydrolase activity 1.06268977958067 bayes_pls_golite062009
catalytic activity 1.05111689766686 bayes_pls_golite062009
phospholipase activity 0.87334512532594 bayes_pls_golite062009
ion transmembrane transporter activity 0.539550637107889 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.49944935937406 bayes_pls_golite062009
cation transmembrane transporter activity 0.486374653947972 bayes_pls_golite062009
lipase activity 0.46273678058621 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.273676921589143 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.266794283648202 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0724768101463518 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle