YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|2098528, gi|2...
Organism: Homo sapiens
Length: 187 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2098528, gi|2....

Description E-value Query
Range
Subject
Range
gi|109106105 - gi|109106105|ref|XP_001093229.1| PREDICTED: ciliary neurotrophic factor [Macaca mulatta]
241.0 [0..1] [187..1]
CNTF - ciliary neurotrophic factor
238.0 [0..1] [187..1]
CNTF_PIG - Ciliary neurotrophic factor OS=Sus scrofa GN=CNTF PE=2 SV=1
236.0 [0..1] [187..1]
CNTF_RABIT - Ciliary neurotrophic factor OS=Oryctolagus cuniculus GN=CNTF PE=1 SV=1
232.0 [0..1] [187..1]
CNTF_RAT - Ciliary neurotrophic factor OS=Rattus norvegicus GN=Cntf PE=1 SV=1
222.0 [0..1] [186..1]
CNTF_MOUSE - Ciliary neurotrophic factor OS=Mus musculus GN=Cntf PE=2 SV=1
218.0 [0..1] [186..1]
gi|61833413 - gi|61833413|ref|XP_607445.1| PREDICTED: similar to ciliary neurotrophic factor [Bos taurus]
215.0 [0..1] [187..1]

Back

Predicted Domain #1
Region A:
Residues: [1-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS  60
   61 TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA 120
  121 YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS 180
  181 SHQTGIP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.522879
Match: 1cnt1
Description: Ciliary neurotrophic factor (CNTF)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytokine receptor binding 6.47223189691244 bayes_pls_golite062009
receptor binding 5.3304255990112 bayes_pls_golite062009
cytokine activity 5.1883241815362 bayes_pls_golite062009
growth factor activity 4.92105782010612 bayes_pls_golite062009
protein binding 3.52041127390038 bayes_pls_golite062009
ciliary neurotrophic factor receptor binding 3.41894439248144 bayes_pls_golite062009
binding 3.38401550405066 bayes_pls_golite062009
growth hormone activity 2.60130826123596 bayes_pls_golite062009
hormone activity 2.52921243340076 bayes_pls_golite062009
prolactin receptor binding 2.45721634350294 bayes_pls_golite062009
interleukin-6 receptor binding 2.37535614986843 bayes_pls_golite062009
interleukin-27 binding 1.83998174953013 bayes_pls_golite062009
transcription regulator activity 1.46377724038658 bayes_pls_golite062009
interleukin-10 receptor binding 1.27984955354659 bayes_pls_golite062009
erythropoietin receptor binding 0.77580300541347 bayes_pls_golite062009
molecular transducer activity 0.470106824402923 bayes_pls_golite062009
signal transducer activity 0.470106824402923 bayes_pls_golite062009
interleukin-12 binding 0.32382333549078 bayes_pls_golite062009
catalytic activity 0.246169290135575 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle