YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|3212317, gi\|3...
Organism:	Homo sapiens
Length:	285 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|3212317, gi|3....

Description	E-value	Query Range	Subject Range
gi\|73998369 - gi\|73998369\|ref\|XP_862878.1\| PREDICTED: similar to Nuclear factor NF-kappa-B p100/p49 subunits (DNA-...	433.0	[0..1]	[285..37]
NFKB2_MOUSE - Nuclear factor NF-kappa-B p100 subunit OS=Mus musculus GN=Nfkb2 PE=1 SV=1	433.0	[0..1]	[285..37]
gi\|55250579, gi\|... - gi\|56605774\|ref\|NP_001008350.1\| nuclear factor of kappa light polypeptide gene enhancer in B-cells 2...	432.0	[0..1]	[285..37]
NFKB2 - nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	431.0	[0..1]	[285..37]
gi\|109090448 - gi\|109090448\|ref\|XP_001104566.1\| PREDICTED: nuclear factor of kappa light polypeptide gene enhancer ...	431.0	[0..1]	[285..37]

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Predicted Domain #1

Region A:
Residues: [1-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPYLVIVEQP KQRGFRFRYG CEGPSHGGLP GASSEKGRKT YPTVKICNYE GPAKIEVDLV  60
   61 THSDPPRAHA HSLVGKQCSE LGICAVSVGP KDMTAQFNNL GVLHVTKKNM MGTMIQKLQR 120
  121 QRLRSRPQGL TEAEQRELEQ EAKELKKVMD LSIVRLRFSA FLRSLPLKPV ISQPIHDSKS 180
  181 PGASNLKISR MDKTAGSVRG GDEVYLLCDK VQKDDIEVRF YEDDENGWQA FGDFSPTDVH 240
  241 KQYAIVFRTP PYHKMKIERP VTVFLQLKRK RGGDVSDSKQ FTYYP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	118.0
Match:	1a3qA
Description:	p52 subunit of NF-kappa B (NFKB); p52 subunit of NF-kappa B (NFKB), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.13591399970354	bayes_pls_golite062009
nucleic acid binding	0.54158309583174	bayes_pls_golite062009
DNA binding	0.53363287856737	bayes_pls_golite062009
transcription regulator activity	0.3602964037518	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: