YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|999791, gi\|999792
Organism:	Escherichia coli
Length:	98 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|999791, gi|999792.

Description	E-value	Query Range	Subject Range
gi\|78701632, gi\|... - gi\|78701632\|ref\|ZP_00866081.1\| Helix-turn-helix, Fis-type [Alkalilimnicola ehrlichei MLHE-1], gi\|785...	107.0	[0..4]	[97..563]
gi\|88925965, gi\|... - gi\|88944328\|ref\|ZP_01147651.1\| Helix-turn-helix, Fis-type [Desulfotomaculum reducens MI-1], gi\|88925...	105.0	[0..4]	[97..356]
gi\|53759887, gi\|... - gi\|91774570\|ref\|YP_544326.1\| two component, sigma54 specific, Fis family transcriptional regulator [...	104.0	[0..4]	[98..357]
gi\|71486651, gi\|... - gi\|71547773\|ref\|ZP_00668332.1\| Helix-turn-helix, Fis-type [Syntrophobacter fumaroxidans MPOB], gi\|71...	103.0	[0..4]	[97..363]
gi\|85774925, gi\|... - gi\|86158414\|ref\|YP_465199.1\| two component, sigma54 specific, Fis family transcriptional regulator [...	103.0	[0..4]	[97..365]
gi\|54297131, gi\|... - gi\|54297131\|ref\|YP_123500.1\| hypothetical protein lpp1176 [Legionella pneumophila str. Paris], gi\|53... gi\|53753950, gi\|... - gi\|54294118\|ref\|YP_126533.1\| hypothetical protein lpl1182 [Legionella pneumophila str. Lens], gi\|537...	102.0	[0..4]	[98..352]
gi\|52628519, gi\|... - gi\|52841408\|ref\|YP_095207.1\| two component response regulator PilR [Legionella pneumophila subsp. pn...	102.0	[0..4]	[98..352]
gi\|98661577 - gi\|98661577\|dbj\|GAA01428.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	101.0	[0..4]	[97..101]
gi\|28203882, gi\|... - gi\|28211441\|ref\|NP_782385.1\| putative sigma-54 interacting protein [Clostridium tetani E88], gi\|2820...	101.0	[0..4]	[97..502]
gi\|91200560 - gi\|91200560\|emb\|CAJ73609.1\| strongly similar to sigma 54 response regulator [Candidatus Kuenenia stu...	101.0	[0..4]	[98..371]

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Predicted Domain #1

Region A:
Residues: [1-98]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFEQRVNSDV LTVSTVNSQD QVTQKPLRDS VKQALKNYFA QLNGQDVNDL YELVLAEVEQ  60
   61 ALLDMVMQYT RGNQTRAALM MGINRGTLRK KLKKYGMN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.09691
Match:	1f36A
Description:	FIS protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.57523737355937	bayes_pls_golite062009
DNA binding	3.00143272905695	bayes_pls_golite062009
nucleic acid binding	2.89825020286436	bayes_pls_golite062009
transcription factor activity	2.53664874743748	bayes_pls_golite062009
binding	1.68817361068715	bayes_pls_golite062009
transcription repressor activity	1.65547085597412	bayes_pls_golite062009
sequence-specific DNA binding	0.46503550280898	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.24108783215685	bayes_pls_golite062009
protein binding	0.111941607625758	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: