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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.689896438372]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
GEA1
  • Golgi cis cisterna
  • Golgi-associated vesicle
    		•
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • intra-Golgi vesicle-mediated transport
  • actin cytoskeleton organization
    		•
  • ARF guanyl-nucleotide exchange factor activity
    		•
    GEA2
  • Golgi cis cisterna
  • Golgi-associated vesicle
    		•
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • intra-Golgi vesicle-mediated transport
  • actin cytoskeleton organization
    		•
  • ARF guanyl-nucleotide exchange factor activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Golgi cis cisterna 2.2737E-6 2 10 2 6292
    Golgi stack 6.0632E-6 2 16 2 6292
    Golgi cisterna 6.0632E-6 2 16 2 6292
    organelle subcompartment 6.0632E-6 2 16 2 6292
    Golgi-associated vesicle 3.9411E-5 2 40 2 6292
    cytoplasmic vesicle 2.8654E-4 2 107 2 6292
    membrane-bounded vesicle 2.8654E-4 2 107 2 6292
    cytoplasmic membrane-bounded vesicle 2.8654E-4 2 107 2 6292
    vesicle 3.0291E-4 2 110 2 6292
    Golgi apparatus part 3.5475E-4 2 119 2 6292
    Golgi apparatus 7.3441E-4 2 171 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    intra-Golgi vesicle-mediated transport 1.1672E-5 2 22 2 6292
    retrograde vesicle-mediated transport, Golgi to ER 1.6421E-5 2 26 2 6292
    ER to Golgi vesicle-mediated transport 1.7194E-4 2 83 2 6292
    actin cytoskeleton organization 3.1973E-4 2 113 2 6292
    actin filament-based process 3.4287E-4 2 117 2 6292
    Golgi vesicle transport 7.0879E-4 2 168 2 6292
    cytoskeleton organization 1.3422E-3 2 231 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ARF guanyl-nucleotide exchange factor activity 7.579E-7 2 6 2 6292
    guanyl-nucleotide exchange factor activity 3.552E-5 2 38 2 6292
    small GTPase regulator activity 8.6451E-5 2 59 2 6292
    GTPase regulator activity 1.7614E-4 2 84 2 6292
    nucleoside-triphosphatase regulator activity 2.256E-4 2 95 2 6292
    enzyme regulator activity 1.0773E-3 2 207 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle