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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.887819369823]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
YAP1801
  • actin cortical patch
    		•
  • endocytosis
    		•
  • clathrin binding
    		•
    YAP1802
  • actin cortical patch
    		•
  • endocytosis
    		•
  • clathrin binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    actin cortical patch 4.1432E-5 2 41 2 6292
    cortical actin cytoskeleton 6.6999E-5 2 52 2 6292
    cortical cytoskeleton 6.6999E-5 2 52 2 6292
    actin cytoskeleton 1.8038E-4 2 85 2 6292
    cell cortex part 2.304E-4 2 96 2 6292
    cell cortex 2.974E-4 2 109 2 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    endocytosis 1.9342E-4 2 88 2 6292
    membrane invagination 2.2085E-4 2 94 2 6292
    membrane organization 9.8542E-4 2 198 2 6292
    cellular membrane organization 9.8542E-4 2 198 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    clathrin binding 2.779E-6 2 11 2 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle