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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classfier did not use Gene Ontology annotations. [FDR: 0.021] [SVM Score: 0.836624764318]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
GCD7
  • mitochondrion
  • guanyl-nucleotide exchange factor complex
  • eukaryotic translation initiation factor 2B complex
    		•
  • regulation of translational initiation
    		•
  • translation initiation factor activity
  • guanyl-nucleotide exchange factor activity
  • enzyme regulator activity
    		•
    GCN3
  • guanyl-nucleotide exchange factor complex
  • eukaryotic translation initiation factor 2B complex
    		•
  • regulation of translational initiation
    		•
  • translation initiation factor activity
  • guanyl-nucleotide exchange factor activity
  • enzyme regulator activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    eukaryotic translation initiation factor 2B complex 5.0527E-7 2 5 2 6292
    guanyl-nucleotide exchange factor complex 1.0611E-6 2 7 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    regulation of translational initiation 2.779E-6 2 11 2 6292
    translational initiation 4.3504E-5 2 42 2 6292
    regulation of translation 8.0641E-5 2 57 2 6292
    posttranscriptional regulation of gene expression 9.2464E-5 2 61 2 6292
    regulation of cellular protein metabolic process 1.151E-4 2 68 2 6292
    regulation of protein metabolic process 1.3647E-4 2 74 2 6292
    translation 3.5621E-3 2 376 2 6292
    regulation of gene expression 4.9915E-3 2 445 2 6292
    regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
    regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
    regulation of biosynthetic process 5.6402E-3 2 473 2 6292
    regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
    regulation of primary metabolic process 6.6615E-3 2 514 2 6292
    regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
    regulation of metabolic process 7.5452E-3 2 547 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    translation initiation factor activity 1.7735E-5 2 27 2 6292
    guanyl-nucleotide exchange factor activity 3.552E-5 2 38 2 6292
    translation factor activity, nucleic acid binding 4.7798E-5 2 44 2 6292
    GTPase regulator activity 1.7614E-4 2 84 2 6292
    nucleoside-triphosphatase regulator activity 2.256E-4 2 95 2 6292
    enzyme regulator activity 1.0773E-3 2 207 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle