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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Isu1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
ISU1
  • mitochondrial matrix
  • mitochondrion
    		•
  • cellular iron ion homeostasis
  • iron-sulfur cluster assembly
    		•
  • protein binding
    		•
    NFS1
  • nucleus
  • mitochondrion
    		•
  • cellular iron ion homeostasis
  • iron-sulfur cluster assembly
    		•
  • tRNA sulfurtransferase activity
  • cysteine desulfurase activity
  • cystathionine gamma-lyase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    metallo-sulfur cluster assembly 3.3348E-6 2 12 2 6292
    iron-sulfur cluster assembly 3.3348E-6 2 12 2 6292
    iron ion homeostasis 3.552E-5 2 38 2 6292
    cellular iron ion homeostasis 3.552E-5 2 38 2 6292
    cellular di-, tri-valent inorganic cation homeostasis 1.0838E-4 2 66 2 6292
    di-, tri-valent inorganic cation homeostasis 1.0838E-4 2 66 2 6292
    cofactor biosynthetic process 1.5966E-4 2 80 2 6292
    cellular cation homeostasis 2.7588E-4 2 105 2 6292
    cation homeostasis 2.974E-4 2 109 2 6292
    cellular chemical homeostasis 3.5475E-4 2 119 2 6292
    cellular ion homeostasis 3.5475E-4 2 119 2 6292
    cellular homeostasis 3.6076E-4 2 120 2 6292
    chemical homeostasis 3.791E-4 2 123 2 6292
    ion homeostasis 3.791E-4 2 123 2 6292
    cofactor metabolic process 5.9526E-4 2 154 2 6292
    homeostatic process 4.1951E-3 2 408 2 6292
    regulation of biological quality 7.6561E-3 2 551 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    tRNA sulfurtransferase activity 6.3568E-4 2 2 1 6292
    cysteine desulfurase activity 6.3568E-4 2 2 1 6292
    cystathionine gamma-lyase activity 9.5344E-4 2 3 1 6292
    transferase activity, transferring sulfur-containing groups 1.2712E-3 2 4 1 6292
    sulfurtransferase activity 1.2712E-3 2 4 1 6292
    carbon-sulfur lyase activity 3.1764E-3 2 10 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle