From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.582939932294] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
FUM1 |
|
|
|
ICL2 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mitochondrial matrix | 7.7811E-4 | 2 | 176 | 2 | 6292 |
mitochondrial lumen | 7.7811E-4 | 2 | 176 | 2 | 6292 |
mitochondrial part | 5.6881E-3 | 2 | 475 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
fumarate metabolic process | 3.1786E-4 | 2 | 1 | 1 | 6292 |
threonine catabolic process | 1.2712E-3 | 2 | 4 | 1 | 6292 |
propionate metabolic process | 1.5888E-3 | 2 | 5 | 1 | 6292 |
organic acid metabolic process | 2.793E-3 | 2 | 333 | 2 | 6292 |
oxoacid metabolic process | 2.793E-3 | 2 | 333 | 2 | 6292 |
carboxylic acid metabolic process | 2.793E-3 | 2 | 333 | 2 | 6292 |
threonine metabolic process | 2.859E-3 | 2 | 9 | 1 | 6292 |
aspartate family amino acid catabolic process | 2.859E-3 | 2 | 9 | 1 | 6292 |
cellular ketone metabolic process | 3.0157E-3 | 2 | 346 | 2 | 6292 |
cellular catabolic process | 4.3405E-3 | 2 | 415 | 2 | 6292 |
acetyl-CoA catabolic process | 4.7627E-3 | 2 | 15 | 1 | 6292 |
tricarboxylic acid cycle | 4.7627E-3 | 2 | 15 | 1 | 6292 |
catabolic process | 6.2027E-3 | 2 | 496 | 2 | 6292 |
acetyl-CoA metabolic process | 6.3477E-3 | 2 | 20 | 1 | 6292 |
coenzyme catabolic process | 6.3477E-3 | 2 | 20 | 1 | 6292 |
cofactor catabolic process | 6.9813E-3 | 2 | 22 | 1 | 6292 |
dicarboxylic acid metabolic process | 9.5139E-3 | 2 | 30 | 1 | 6292 |
cellular amino acid catabolic process | 9.5139E-3 | 2 | 30 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
lyase activity | 1.9342E-4 | 2 | 88 | 2 | 6292 |
methylisocitrate lyase activity | 3.1786E-4 | 2 | 1 | 1 | 6292 |
fumarate hydratase activity | 3.1786E-4 | 2 | 1 | 1 | 6292 |
oxo-acid-lyase activity | 1.2712E-3 | 2 | 4 | 1 | 6292 |
hydro-lyase activity | 8.5646E-3 | 2 | 27 | 1 | 6292 |
carbon-carbon lyase activity | 9.5139E-3 | 2 | 30 | 1 | 6292 |