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Protein Overview: PSF3

General Information:
Name(s) found: PSF3 / YOL146W [SGD]
Description(s) found:
Found 17 descriptions.
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  • Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 194 amino acids

    Gene Ontology:
    Cellular Component: GINS complex [IPILink to PubMed articleLink to PubMed article]
    Biological Process: DNA-dependent DNA replication [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYYDIDDVL ADGTEFPCKF QYDIPGLGYL ENNPGRPITK NTKLSLPLWL ARILAIVGGD  60
   61 EALVDEEPVP FVELLPPDMF STKVMNAIKT DPVALDLHSI NSHFFSLAIK WIMLFSEKEL 120
  121 ANVVSELLLQ RAQELNHHAS SLSIDLNADS TGKNSANTNI ATSTFLLKLE EMEKEIYKKS 180
  181 HESYKDTKRW MFKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) PSF1 PSF2 PSF3 SLD5
    View Details Hazbun TR, et al. (2003) PSF1 PSF2 PSF3 SLD5
    View Details (MIPS) Mewes HW, et al. (2004) PSF1 PSF2 PSF3 SLD5
    View Details Krogan NJ, et al. (2006) CTF4 PSF1 PSF2 PSF3 SLD5
    View Details Qiu et al. (2008) PSF1 PSF2 PSF3 SLD5

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PSF3 YCL056C 2 Hazbun TR, et al. (2003)
    View Screen PSF3 HAP5 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..194] Pfam 9.337242 No description for PF06425.1 was found. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3'-5' DNA helicase activity
    		•  3.30007058745861 bayes_pls_golite062009
  • DNA helicase activity
    		•  2.7662250039458 bayes_pls_golite062009
  • binding
    		•  1.27082628880017 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.2336233528067 bayes_pls_golite062009
  • helicase activity
    		•  1.2110072302388 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  0.37490315580617 bayes_pls_golite062009
  • catalytic activity
    		•  0.161911144249814 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle