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Protein Overview: HNT1

General Information:
Name(s) found: HNT1 / YDL125C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 158 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Biological Process: nucleotide metabolic process [IDALink to PubMed article]
    Molecular Function: nucleotide binding [ISSLink to PubMed article]
    hydrolase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPLISAPYL TTTKMSAPAT LDAACIFCKI IKSEIPSFKL IETKYSYAFL DIQPTAEGHA  60
   61 LIIPKYHGAK LHDIPDEFLT DAMPIAKRLA KAMKLDTYNV LQNNGKIAHQ EVDHVHFHLI 120
  121 PKRDEKSGLI VGWPAQETDF DKLGKLHKEL LAKLEGSD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AIM3 BAR1 COA4 GYL1 GYP5 HNT1 KIN2 MEF2 NCP1 PCL10 PRP28 RVS161 RVS167 SAE2 SLK19 TIM21 VPS15

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen HNT1 TSA2 2 Unpublished Fields Lab Data
    View Screen HNT1 PTP3 2 Unpublished Fields Lab Data
    View Screen HNT1 MET2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data HNT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..158] PSI-BLAST 124.0 Protein kinase C inhibitor-1, PKCI-1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.71599870633602 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.724655038971066 bayes_pls_golite062009
  • protein binding
    		•  0.315946879872005 bayes_pls_golite062009
  • catalytic activity
    		•  0.096119422680995 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle