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Protein Overview: MNN2

General Information:
Name(s) found: MNN2 / YBR015C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 597 amino acids

    Gene Ontology:
    Cellular Component: Golgi apparatus [IDALink to PubMed article]
    Biological Process: protein amino acid glycosylation [IMPLink to PubMed article]
    Molecular Function: alpha-1,2-mannosyltransferase activity [IMPLink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLTKRFSKL FKLTFIVLIL CGLFVITNKY MDENTSVKEY KEYLDRYVQS YSNKYSSSSD  60
   61 AASADDSTPL RDNDEAGNEK LKSFYNNVFN FLMVDSPKGS TAKQYNEACL LKGDIGDRPD 120
  121 HYKDLYKLSA KELSKCLELS PDEVASLTKS HKDYVEHIAT LVSPKGTYKG SGIATVGGGK 180
  181 FSLMAFLIIK TLRNMGTTLP VEVLIPPGDE GETEFCNKIL PKYNSKCIYV SDILPRETIE 240
  241 KFVFKGYQFK SLALIASSFE NLLLLDADNF PIKPLDNIFN EEPYVSTGLV MWPDFWRRTT 300
  301 HPLYYDIAGI AVDKKKRVRN SRDDITPPAV YTKDLKDLSD VPLSDLDGTI PDVSTESGQL 360
  361 MINKTKHLAT ALLSLFYNVN GPTWYYPIFS QKAAGEGDKE TFIAAANFYG LSFYQVRTRT 420
  421 GVEGYHDEDG FHGVAMLQHD FVQDYGRYLN AMESIGNKYG GTKSADAIKF DKNYSLEKYT 480
  481 EEFFDNEDLN AKNHVDVMFI HSNFPKFDPY DLSKSNFLTT NGKPARSYTA LKKVKNYDIE 540
  541 LENFKVLNEY VCVNKNPFKY LDDLLGQDKT EWKRVCGYIT DRLAFLESTH DKAIAGK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ANP1 MNN2 MNN5

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen ROM2 MNN2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MNN2 and ANP1 Huh WK, et al. (2003)
    View Data MNN2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..119] deduced N/A No confident structure predictions are available.
    2 View Details [120..313] ORFEUS 7.52 Glycogenin
    3 View Details [314..597] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • mannosyltransferase activity
    		•  5.1732667004955 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  4.02812104984198 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  3.59185576348855 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  3.3757785630345 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  2.9474291454591 bayes_pls_golite062009
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  2.69652752452892 bayes_pls_golite062009
  • transferase activity
    		•  2.3313878748424 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.24840829900507 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.79751747857925 bayes_pls_golite062009
  • catalytic activity
    		•  1.73979371332125 bayes_pls_golite062009
  • binding
    		•  0.75831291352972 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.641710647713692 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle