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Protein Overview: gi|77627992, gi|...

General Information:
Name(s) found: gi|77627992 [NCBI NR]
gi|66969456 [NCBI NR]
gi|27667260 [NCBI NR]
Description(s) found:
Found 15 descriptions.
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  • gi|77627992|ref|NP_001029277.1| troponin C type 1 (slow) [Rattus norvegicus] [NCBI NR]
  • gi|66969456|gb|AAY59902.1| cardiac troponin C [Rattus norvegicus] [NCBI NR]
  • ref|XP_214266.1| similar to troponin C, cardiac muscle - mouse [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 161 amino acids

    Gene Ontology:
    Cellular Component: contractile fiber [IDA]
    troponin complex [UNKNOWN][IEA]
    Biological Process: ventricular cardiac muscle tissue morphogenesis [UNKNOWN][IEA]
    regulation of ATPase activity [IEA]
    regulation of muscle contraction [UNKNOWN][IEA]
    response to metal ion [IDA]
    regulation of muscle filament sliding speed [IEA]
    diaphragm contraction [IDA]
    cardiac muscle contraction [UNKNOWN][IMP]
    Molecular Function: actin filament binding [IEA]
    protein binding [UNKNOWN]
    protein homodimerization activity [UNKNOWN][IEA]
    calcium ion binding [UNKNOWN][IDA]
    troponin I binding [UNKNOWN][IEA]
    calcium-dependent protein binding [UNKNOWN][IEA]
    troponin T binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVMRMLGQ NPTPEELQEM  60
   61 IDEVDEDGSG TVDFDEFLVM MVRCMKDDSK GKSEEELSDL FRMFDKNADG YIDLDELKMM 120
  121 LQATGETITE DDIEELMKDG DKNNDGRIDY DEFLEFMKGV E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..161] PSI-BLAST 26.0 Troponin C

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • troponin T binding
    		•  7.68526659589559 bayes_pls_golite062009
  • structural constituent of muscle
    		•  6.34041234021534 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  6.31366142616096 bayes_pls_golite062009
  • N-terminal myristoylation domain binding
    		•  5.746886320739 bayes_pls_golite062009
  • microfilament motor activity
    		•  5.62061944255026 bayes_pls_golite062009
  • G-protein beta/gamma-subunit binding
    		•  5.51712867097471 bayes_pls_golite062009
  • myosin II heavy chain binding
    		•  5.49688740358168 bayes_pls_golite062009
  • actin binding
    		•  3.96919556235483 bayes_pls_golite062009
  • calcium ion binding
    		•  3.79609619542776 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  3.63014173976595 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.49668552859347 bayes_pls_golite062009
  • motor activity
    		•  3.25814691068414 bayes_pls_golite062009
  • binding
    		•  3.17556402087346 bayes_pls_golite062009
  • cation binding
    		•  2.62077305565026 bayes_pls_golite062009
  • metal ion binding
    		•  2.62077305565026 bayes_pls_golite062009
  • ion binding
    		•  2.61312132078717 bayes_pls_golite062009
  • tubulin binding
    		•  2.51210014078446 bayes_pls_golite062009
  • actin filament binding
    		•  2.35534489389161 bayes_pls_golite062009
  • myosin binding
    		•  2.34125070430971 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.29802198409541 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.28098452079347 bayes_pls_golite062009
  • calcium sensitive guanylate cyclase activator activity
    		•  2.25146252368284 bayes_pls_golite062009
  • microtubule binding
    		•  2.17136406283012 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.12961051741613 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.74951443813569 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.51057181410195 bayes_pls_golite062009
  • kinase activity
    		•  1.48008348280256 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.34982153616582 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.29595371278065 bayes_pls_golite062009
  • protein binding
    		•  1.16246005294206 bayes_pls_golite062009
  • transporter activity
    		•  1.15928534291452 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.11607939838219 bayes_pls_golite062009
  • signal transducer activity
    		•  1.11607939838219 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.02715871704923 bayes_pls_golite062009
  • transferase activity
    		•  1.00143834284844 bayes_pls_golite062009
  • actin monomer binding
    		•  0.9954841049256 bayes_pls_golite062009
  • DNA binding
    		•  0.98588735736701 bayes_pls_golite062009
  • nitric-oxide synthase binding
    		•  0.965098383344279 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.945691505472547 bayes_pls_golite062009
  • cation channel activity
    		•  0.856991182112951 bayes_pls_golite062009
  • guanylate cyclase regulator activity
    		•  0.84389905735679 bayes_pls_golite062009
  • cyclase regulator activity
    		•  0.84389905735679 bayes_pls_golite062009
  • structural molecule activity
    		•  0.800850121197479 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.438908712437433 bayes_pls_golite062009
  • hydrolase activity
    		•  0.378268353045111 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.366129174039334 bayes_pls_golite062009
    		• 0.34446792626966 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.341357838238159 bayes_pls_golite062009
  • channel regulator activity
    		•  0.32809521759917 bayes_pls_golite062009
  • myosin II binding
    		•  0.311147527050891 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.308919475701377 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.304496519713588 bayes_pls_golite062009
  • potassium channel activity
    		•  0.260530997378698 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.246383459363256 bayes_pls_golite062009
  • ER retention sequence binding
    		•  0.234166588492671 bayes_pls_golite062009
  • gated channel activity
    		•  0.175191914660841 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.157059988605635 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.116648335890738 bayes_pls_golite062009
  • channel activity
    		•  0.0711800677928949 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.0711800677928949 bayes_pls_golite062009
  • receptor binding
    		•  0.0645779132227158 bayes_pls_golite062009
  • ion channel activity
    		•  0.0166394982861724 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle