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Protein Overview: SYA_SALTI

General Information:
Name(s) found: SYA_SALTI [Swiss-Prot]
Description(s) found:
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  • gi|20532252|sp|Q8Z4D5.1|SYA_SALTI RecName: Full=Alanyl-tRNA synthetase; AltName: Full=Alanine--tRNA ligase; Short=AlaRS [NCBI NR]
  • Alanyl-tRNA synthetase OS=Salmonella typhi GN=alaS PE=3 SV=1 [Swiss-Prot]
  • alanyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar Typhi Ty2]gi|16761603|ref|NP_457220.1| alanyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar Typhi str. CT18]gi|29138720|gb|AAO70289.1| alanyl-tRNA synthetase [Salmonella [nrdb_11152004_Chlamydomonas]
  • Alanine--tRNA ligase OS=Salmonella typhi GN=alaS PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Salmonella typhi
    Length: 876 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSTAEIRQ AFLDFFHSKG HQVVASSSLV PNNDPTLLFT NAGMNQFKDV FLGLDKRNYS  60
   61 RATTSQRCVR AGGKHNDLEN VGYTARHHTF FEMLGNFSFG DYFKHDAIQF AWELLTGENW 120
  121 FALPKERLWV TVYETDDEAY EIWEKEVGIP RERIIRIGDN KGAPYASDNF WQMGDTGPCG 180
  181 PCTEIFYDHG DHIWGGPPGS PEEDGDRYIE IWNIVFMQFN RQADGTMEPL PKPSVDTGMG 240
  241 LERIAAVLQH VNSNYDIDLF RTLIEAVAKV TGSTDLGNKS LRVIADHIRS CAFLVADGVL 300
  301 PSNENRGYVL RRIIRRAVRH GNMLGAKETF FYKLVGPLIE VMGSAGEELK RQQAQVEQVL 360
  361 KTEEEQFART LERGLALLDE ELAKLQGDTL DGETAFRLYD TYGFPVDLTA DVCRERNIKV 420
  421 DEAGFEAAME EQRRRAREAS GFGADYNAMI RVDSASEFKG YDHLELNGKV TALFVDGKAV 480
  481 EAINAGQEAV VVLDQTPFYA ESGGQVGDKG ELKGAGFTFA VDDTQKYGQA IGHLGKLSAG 540
  541 ALKVGDAVQA DVDEARRARI RLNHSATHLM HAALRQVLGT HVAQKGSLVS DKVLRFDFSH 600
  601 NEAMKPSEIR EVEDLVNAQI RRNLPIETNI MDLDAAKAKG AMALFGEKYD ERVRVLSMGD 660
  661 FSTELCGGTH ASRTGDIGLF RIISESGTAA GIRRIEAVTG EGAMATVHAQ SDRLNDIAHL 720
  721 LKGDSQNLGD KVRAVLERTR QLEKELQQLK DQAAAQESAN LSSKAVDLNG VKLLVSELAG 780
  781 IEPKMLRTMV DDLKNQLGST VIVLATVVEG KVSLIAGVSK DVTDRVKAGE LIGMVAQQVG 840
  841 GKGGGRPDMA QAGGTDAAAL PAALASVQGW VSAKLQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..466] PSI-BLAST 1000.0 The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase
    2 View Details [467..809] PSI-BLAST 58.0 Structure of Staphylococcus aureus threonyl-tRNA synthetase complexed with an analogue of threonyl adenylate
    3 View Details [810..876] Pfam 12.853872 No description for PF02272.10 was found. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.89468709683036 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.89468709683036 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.88410036819636 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  6.00693881794242 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  2.99105702052936 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.46505535069103 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.29229136935761 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  1.72324031407565 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.47976803533584 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.30216701059664 bayes_pls_golite062009
  • DNA binding
    		•  1.1862497958336 bayes_pls_golite062009
  • binding
    		•  1.11470390774037 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.921492123574877 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.80781620905336 bayes_pls_golite062009
  • transcription factor activity
    		•  0.566858624145031 bayes_pls_golite062009
  • RNA binding
    		•  0.0221706730298825 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.00572514744734753 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle