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Protein Overview: PTFAH_ECOLI, PTF...

General Information:
Name(s) found: PTFA_ECOLI [Swiss-Prot]
PTFAH_ECOLI [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • (P24217) PTS system, fructose-specific IIA/FPr component (EIIA-Fru) (Fructose-permease IIA/FPr component) (Phosphotransferase enzyme II, A/FPr component) (EC 2.7.1.69) (Phosphotransferase FPr protein) (Pseudo-HPr) (EIII-Fru) (Fructose PTS diph [Swiss-Prot]
  • Multiphosphoryl transfer protein (MTP) (Phosphotransferase FPr protein) (Pseudo-HPr) [Includes: Phosphocarrier protein HPr (Protein H); Fructose-specific phosphotransferase enzyme IIA component (EC 2.7.1.-) (PTS system fructose-specific EIIA component)] - [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 376 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQLSVQDIH PGEKAGDKEE AIRQVAAALV QAGNVAEGYV NGMLAREQQT STFLGNGIAI  60
   61 PHGTTDTRDQ VLKTGVQVFQ FPEGVTWGDG QVAYVAIGIA ASSDEHLGLL RQLTHVLSDD 120
  121 SVAEQLKSAT TAEELRALLM GEKQSEQLKL DNEMLTLDIV ASDLLTLQAL NAARLKEAGA 180
  181 VDATFVTKAI NEQPLNLGQG IWLSDSAEGN LRSAIAVSRA ANAFDVDGET AAMLVSVAMN 240
  241 DDQPIAVLKR LADLLLDNKA DRLLKADAAT LLALLTSDDA PTDDVLSAEF VVRNEHGLHA 300
  301 RPGTMLVNTI KQFNSDITVT NLDGTGKPAN GRSLMKVVAL GVKKGHRLRF TAQGADAEQA 360
  361 LKAIGDAIAA GLGEGA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..142] PSI-BLAST 34.30103 Phosphotransferase IIa-mannitol
    2 View Details [143..267] PSI-BLAST 9.221849 No description for 2r4qA was found.
    3 View Details [268..376] PSI-BLAST 20.30103 Histidine-containing phosphocarrier protein (HPr)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
    		•  4.89047341597444 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  3.92377913213665 bayes_pls_golite062009
  • transporter activity
    		•  2.16741930408232 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.05879816720019 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.87457143976439 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.82451780056478 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.7251575499811 bayes_pls_golite062009
  • binding
    		•  0.396676636991646 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.19707628828681 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.12881601139602 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  0.10209580008722 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
    		•  5.70778264466435 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  4.7398246519874 bayes_pls_golite062009
  • transporter activity
    		•  1.94557075462337 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.8285077384404 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.73790085561506 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.57976971135135 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.4723961195197 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.97685688328333 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.61783246115451 bayes_pls_golite062009
  • binding
    		•  0.569728786489819 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle