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Protein Overview: MAO2_ECOLI

General Information:
Name(s) found: MAO2_ECOLI [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
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  • NADP-dependent malic enzyme (EC 1.1.1.40) (NADP-ME) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 759 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDQLKQSAL DFHEFPVPGK IQVSPTKPLA TQRDLALAYS PGVAAPCLEI EKDPLKAYKY  60
   61 TARGNLVAVI SNGTAVLGLG NIGALAGKPV MEGKGVLFKK FAGIDVFDIE VDELDPDKFI 120
  121 EVVAALEPTF GGINLEDIKA PECFYIEQKL RERMNIPVFH DDQHGTAIIS TAAILNGLRV 180
  181 VEKNISDVRM VVSGAGAAAI ACMNLLVALG LQKHNIVVCD SKGVIYQGRE PNMAETKAAY 240
  241 AVVDDGKRTL DDVIEGADIF LGCSGPKVLT QEMVKKMARA PMILALANPE PEILPPLAKE 300
  301 VRPDAIICTG RSDYPNQVNN VLCFPFIFRG ALDVGATAIN EEMKLAAVRA IAELAHAEQS 360
  361 EVVASAYGDQ DLSFGPEYII PKPFDPRLIV KIAPAVAKAA MESGVATRPI ADFDVYIDKL 420
  421 TEFVYKTNLF MKPIFSQARK APKRVVLPEG EEARVLHATQ ELVTLGLAKP ILIGRPNVIE 480
  481 MRIQKLGLQI KAGVDFEIVN NESDPRFKEY WTEYFQIMKR RGVTQEQAQR ALISNPTVIG 540
  541 AIMVQRGEAD AMICGTVGDY HEHFSVVKNV FGYRDGVHTA GAMNALLLPS GNTFIADTYV 600
  601 NDEPDAEELA EITLMAAETV RRFGIEPRVA LLSHSNFGSS DCPSSSKMRQ ALELVRERAP 660
  661 ELMIDGEMHG DAALVEAIRN DRMPDSSLKG SANILVMPNM EAARISYNLL RVSSSEGVTV 720
  721 GPVLMGVAKP VHVLTPIASV RRIVNMVALA VVEAQTQPL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..429] PSI-BLAST 118.0 No description for 1ww8A was found.
    2 View Details [430..759] PSI-BLAST 88.69897 Crystal Structure of a Phosphotransacetylase from Streptococcus pyogenes

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • isocitrate dehydrogenase activity
    		•  4.33689457213697 bayes_pls_golite062009
  • isocitrate dehydrogenase (NAD+) activity
    		•  3.02706047421851 bayes_pls_golite062009
  • catalytic activity
    		•  2.71251959637136 bayes_pls_golite062009
  • isocitrate dehydrogenase (NADP+) activity
    		•  2.58800454678946 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  2.5212640632502 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.34383793575786 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.23338300186555 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.23134321553105 bayes_pls_golite062009
  • acetyltransferase activity
    		•  0.475874744828042 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle