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Protein Overview: CYCA_ECOLI

General Information:
Name(s) found: CYCA_ECOLI [Swiss-Prot]
Description(s) found:
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  • gi|77416678|sp|P0AAE0.1|CYCA_ECOLI RecName: Full=D-serine/D-alanine/glycine transporter [NCBI NR]
  • gi|537049|gb|AAA97104.1| ORF_o470 [Escherichia coli] [NCBI NR]
  • pir||B91277 D-serine/D-alanine/glycine transporter [similarity] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) [NCBI NR]
  • pir||B86118 transport of D-alanine, D-serine, and glycine [imported] - Escherichia coli (strain O157:H7, substrain EDL933) [NCBI NR]
  • gi|209749946|gb|ACI73280.1| transport protein of D-alanine / D-serine / glycine [Escherichia coli] [NCBI NR]
  • gi|209749944|gb|ACI73279.1| transport protein of D-alanine / D-serine / glycine [Escherichia coli] [NCBI NR]
  • gi|209749942|gb|ACI73278.1| transport protein of D-alanine / D-serine / glycine [Escherichia coli] [NCBI NR]
  • gi|209749938|gb|ACI73276.1| transport protein of D-alanine / D-serine / glycine [Escherichia coli] [NCBI NR]
  • pir||S56433 D-serine/D-alanine/glycine transporter - Escherichia coli (strain K-12) [NCBI NR]
  • D-serine/D-alanine/glycine transporter - Escherichia coli [Swiss-Prot]
  • D-alanine/D-serine/glycine transport protein (APC family); transport of D-alanine, D-serine, and glycine [Escherichia coli K12]gi|15834440|ref|NP_313213.1| CycA; transport protein of D-alanine/D-serine/glycine [Escherichia coli O157:H7]gi|15804799|ref|N [nrdb_11152004_Chlamydomonas]
  • D-serine/D-alanine/glycine transporter [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • ORF_o470 [Escherichia coli] [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • D-serine/D-alanine/glycine transporter OS=Escherichia coli (strain K12) GN=cycA PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 470 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDQVKVVAD DQAPAEQSLR RNLTNRHIQL IAIGGAIGTG LFMGSGKTIS LAGPSIIFVY  60
   61 MIIGFMLFFV MRAMGELLLS NLEYKSFSDF ASDLLGPWAG YFTGWTYWFC WVVTGMADVV 120
  121 AITAYAQFWF PDLSDWVASL AVIVLLLTLN LATVKMFGEM EFWFAMIKIV AIVSLIVVGL 180
  181 VMVAMHFQSP TGVEASFAHL WNDGGWFPKG LSGFFAGFQI AVFAFVGIEL VGTTAAETKD 240
  241 PEKSLPRAIN SIPIRIIMFY VFALIVIMSV TPWSSVVPEK SPFVELFVLV GLPAAASVIN 300
  301 FVVLTSAASS ANSGVFSTSR MLFGLAQEGV APKAFAKLSK RAVPAKGLTF SCICLLGGVV 360
  361 MLYVNPSVIG AFTMITTVSA ILFMFVWTII LCSYLVYRKQ RPHLHEKSIY KMPLGKLMCW 420
  421 VCMAFFVFVV VLLTLEDDTR QALLVTPLWF IALGLGWLFI GKKRAAELRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..470] FFAS03 1.34 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • amine transmembrane transporter activity
    		•  5.15069657292327 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  4.54752581624334 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  4.39427743642027 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  4.356142166703 bayes_pls_golite062009
  • transporter activity
    		•  3.46503611631839 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.34431027577801 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.08398439124803 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.98812190037621 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.96577701947757 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.89542769737674 bayes_pls_golite062009
  • organic acid:sodium symporter activity
    		•  1.82263833070018 bayes_pls_golite062009
  • L-amino acid transmembrane transporter activity
    		•  1.79964917042361 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79923665576923 bayes_pls_golite062009
  • neutral amino acid transmembrane transporter activity
    		•  1.71764370341895 bayes_pls_golite062009
  • monoamine transmembrane transporter activity
    		•  1.59349600647168 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.37015067735708 bayes_pls_golite062009
  • symporter activity
    		•  1.31198147603118 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  1.31198147603118 bayes_pls_golite062009
  • solute:sodium symporter activity
    		•  0.868753445363102 bayes_pls_golite062009
  • neurotransmitter:sodium symporter activity
    		•  0.658077875061275 bayes_pls_golite062009
  • binding
    		•  0.299468111884938 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle