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Protein Overview: CLCA_ECOLI

General Information:
Name(s) found: CLCA_ECOLI [Swiss-Prot]
Description(s) found:
Found 24 descriptions.
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  • H(+)/Cl(-) exchange transporter clcA (ClC-ec1) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 473 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTDTPSLET PQAARLRRRQ LIRQLLERDK TPLAILFMAA VVGTLVGLAA VAFDKGVAWL  60
   61 QNQRMGALVH TADNYPLLLT VAFLCSAVLA MFGYFLVRKY APEAGGSGIP EIEGALEDQR 120
  121 PVRWWRVLPV KFFGGLGTLG GGMVLGREGP TVQIGGNIGR MVLDIFRLKG DEARHTLLAT 180
  181 GAAAGLAAAF NAPLAGILFI IEEMRPQFRY TLISIKAVFI GVIMSTIMYR IFNHEVALID 240
  241 VGKLSDAPLN TLWLYLILGI IFGIFGPIFN KWVLGMQDLL HRVHGGNITK WVLMGGAIGG 300
  301 LCGLLGFVAP ATSGGGFNLI PIATAGNFSM GMLVFIFVAR VITTLLCFSS GAPGGIFAPM 360
  361 LALGTVLGTA FGMVAVELFP QYHLEAGTFA IAGMGALLAA SIRAPLTGII LVLEMTDNYQ 420
  421 LILPMIITGL GATLLAQFTG GKPLYSAILA RTLAKQEAEQ LARSKAASAS ENT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..473] PSI-BLAST 80.69897 Clc chloride channel

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • anion channel activity
    		•  5.23649338477108 bayes_pls_golite062009
  • chloride channel activity
    		•  5.23649338477108 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  4.7823647688311 bayes_pls_golite062009
  • voltage-gated chloride channel activity
    		•  4.66898411574669 bayes_pls_golite062009
  • voltage-gated anion channel activity
    		•  4.66898411574669 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.29532156100584 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.9211909958998 bayes_pls_golite062009
  • ion channel activity
    		•  2.47371003999085 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  2.3506930471942 bayes_pls_golite062009
  • channel activity
    		•  2.34190943501298 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  2.34190943501298 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  1.83450427449366 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  1.82456160587504 bayes_pls_golite062009
  • gated channel activity
    		•  1.60884925346186 bayes_pls_golite062009
  • transporter activity
    		•  1.42882449395305 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.27364043073575 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.11689211993777 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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